I hope this is ok for me to post. if its not please remove.
I will be reacting Lysergic Acid with
1.O-alkylation: The ethyl group attaches to the oxygen, creating ethyl lysergate.
2.this will then undergo aminolysis, back to an amide via diethylamide.
3.**Interesting thing**
If it goes wrong, i will end up with a resulting compound with a quaternary ammonium ester salt.
To be more precise, it would be the ethyl ester of N-ethyl-lysergic ammonium triflate.
should i not do this under extreme low temperatures.
Hopefully the resulting product is interesting.
Proper PPE will be used of course.
I will be reacting Lysergic Acid with
Ethyl trifluoromethanesulfonate.
I will be doing this in dry ice with acetone, looking to achieve esterfercation under -78c conditions.1.O-alkylation: The ethyl group attaches to the oxygen, creating ethyl lysergate.
2.this will then undergo aminolysis, back to an amide via diethylamide.
3.**Interesting thing**
If it goes wrong, i will end up with a resulting compound with a quaternary ammonium ester salt.
To be more precise, it would be the ethyl ester of N-ethyl-lysergic ammonium triflate.
should i not do this under extreme low temperatures.
Hopefully the resulting product is interesting.
Proper PPE will be used of course.
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