dragonrider said:
Yeah, i knew about the beaocystin and norbeaocystin. P.azurescens, another favorite of mine, also is reported to contain those 'analogue's'. But sometimes there are other tryptamines present in shrooms as well. Tryptophan is just one i know of from the back of my head, but there are more of these kind of substances, often with unknown effects. I suppose tryptophan would definately have noticeable effects in combination with rue or caapi.
Could you provide a source which details these "other tryptamine" compounds which are found in psilocybe fungi?
Correct me if I'm wrong, but The only tryptamines known to be found in psilocybe fungi are:
·4-phosphorloxy-N,N-Dimethyltryptamine
·4-hydroxy-N,N-Dimethyltryptamine
·4-phosphorloxy-N-methyl-tryptamine
·4-hydroxy-N-methyl-tryptamine
*N,N,N-trimethyl-4-phosphoryloxytryptamine; Aeruginascin (only found in Pholiotina cyanopus* and Inocybe aeruginascens)
*dimethyltryptamine (as intermediate in biosynthesis)
*N-methyl-tryptamine (as intermediate in biosynthesis)
*tryptamine (as intermediate in biosynthesis)
*5-hydroxy-tryptamine (serotonin) (generally present in Panaeolus or Copelandia species)
Tryptophan can be found in psilocybe fungi, but it's not a product of the fungi, it's derived from the environment, and tryptophan is not a tryptamine, it's an amino acid.
Strangely enough, phenethylamine is said to be found in certain species of psilocybe fungi, and is said to alter the effects produced by the N-alkylated tryptamines present:
Presence of phenylethylamine in hallucinogenic Psilocybe mushroom: possible role in adverse reactions.
Abstract
The use of mushrooms containing the hallucinogenic substance psilocybin for intentional intoxication is relatively common. Occasionally, this results in adverse reactions with typical tachycardia that is not evidently caused by psilocybin. This study demonstrates the presence of phenylethylamine in the species Psilocybe semilanceata using gas chromatography-mass spectrometry and shows that the amount of this substance may vary much more than that of psilocybin. The highest amount of phenylethylamine (146 microg/g wet weight) was observed in mushrooms from a case of three young men hospitalized because of adverse reactions. Comparison of the symptoms observed in clinical cases of magic mushroom intoxication with those after intake of pure psilocybin or phenylethylamine suggests that phenylethylamine might have a role in the development of adverse reactions to Psilocybe mushroom intake.
Presence of phenylethylamine in hallucinogenic Psilocybe mushroom: possible role in adverse reactions - PubMed
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*
Abstract
Pholiotina cyanopus was collected from wood chips and other woody remnants of undetermined tree species. Its basidiomata were found in June within the area of closed sawmill in the central part of Żywiec city (SW Poland). Description and illustration of Ph. cyanopus based on Polish specimens are provided and its ecology, general distribution and comparison with similar taxa – Pholiotina smithii, Pholiotina sulcatipes, and others are discussed as well. The identity of the active compounds of Ph. cyanopus was additionally determined. Liquid chromatography–mass spectrometry (LC-MS) data sets were obtained to support the occurrence of psilocybin and its analogues – psilocin, baeocystin, norbaeocystin, and aeruginascin in air-dried basidiomata of the species. The content of psilocybin was found to be high (0.90±0.08% of dry weight), besides, analysed samples contained lower concentrations of psilocin (0.17±0.01%), and baeocystin (0.16±0.01%). Additionally, the chemical analysis revealed small amounts of norbaeocystin (0.053±0.004%) and aeruginascin (0.011±0.0007%) for the first time in the species.
https://www.researchgate.net/public...are_fungus_producing_psychoactive_tryptamines
-eg
