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The prelude to a deeper and more intense trip to hyperspace

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starway7

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Vaporhuasca....
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I LEARNED TO LOVE AGAIN ON VAPORHUASCA
Armed with DMT cartridges and a plant called Syrian rue, this psychonaut tripped his way to a new lease on life

The powerful hallucinogen DMT ranks high on the psychedelic pecking order. It sends users on a mighty voyage that even seasoned psychonauts have trouble putting into words (studies suggest that DMT trips model near-death experiences). Yet, there are brave souls who endeavor to descend even deeper into the great beyond. They purposefully increase the potency of their DMT by combining it with the seeds of a plant called Syrian rue, and the outcome is a trip closer to that brought on by the psychedelic powerhouse Ayahuasca.

Rob, a 44-year-old YouTuber who runs the channel Adeptus Psychonautica, which is devoted to psychedelics, tells me that this vigor-enhancing effect is due to an enzyme that exists throughout our bodies called monoamine oxidase (MAO). Normally, MAO spends its time deactivating monoamine neurotransmitters like dopamine, noradrenaline and serotonin once they’ve served their purpose. However, there are chemicals that can stop our MAO enzymes from doing their jobs — they’re known as monoamine oxidase inhibitors (MAOIs), and as Rob explains, Syrian rue contains several called harmala alkaloids (more specifically, the compounds in Syrian rue are a subclass of MAOIs known as reversible inhibitors of monoamine oxidase A, or RIMAs).


That means, if you ingest Syrian rue seeds — where the harmala alkaloids are concentrated — before taking a psychedelic such as DMT, they’ll stop decommissioning the neurotransmitters the drug produces. They build up in your body, and as Rob says, “This leads to a much more vivid and longer-lasting trip.” He even goes as far as saying the combination is “probably the most powerful psychedelic substance on the planet.


 
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