I more or less agree with this. While intuitively it's difficult for me to admit it, technically it makes sense. To state something as a fact is to proclaim it unquestionably and irrefutably "true".
But what is truth if not an ever-changing state of being?
All science does is find the truth that applies to a certain concept in a certain moment of time based on a certain set of criteria and assumptions. But the most important aspect of science, as Terence said in one of his most legendary talks, is that it's capable of undergoing its own reform, and has been involved in that for quite some time now.
Even saying the only "fact" is that the only guarantee in this universe is the state of constant change would assume that a state of no change does not exist, which already relies in a bunch of assumptions and perspectives (or lack thereof).
It's a difficult topic, this one, as most of Nietzsche's work.