So, I finally give nebulizing DMT a try..
All and all a cool experiment, having "vaped" DMT-Fumerate.
And it's an interesting method using room temp droplets instead of heat.
Dissolved 771mg DMT-Fumerate in 2ml water and loaded it into the Omron A3.
The Omron has 3 mist drop size settings:
1: large drops at 0.7ml/min
2: medium drops at 0.5ml/min
3: small drops at 0.3ml/min
I used settings 3 because the manual said that the smallest drops penetrate deepest into the lungs. Inhaled for 10 seconds 3 times (30 sec total). Holding breath for 10 seconds after each inhalation. Inhaling vapor was easy. Effect: very mild. Open eyed visuals, carpet moving etc, nothing special. Afterward felt a very mild burning sensation in deep throat and lungs, which disappeared after a couple of minutes. As if it dissolved away slowly.
30 min later second try. Inhaled 4x 13 second inhalations (50 seconds total). Holding breath for 10 seconds after each inhalation. Nice CEV going on. Felt nice also. No break through. Opened eyes around 5min later. Everything was moving intense. It worked!
But not very efficient.. 771mg DMT-Fum in 2000ml water is 28% DMT-Fum. The Omron manual states the device outputs 0.3ml/min on setting 3. That's around 2mg DMT-Fum per second (2ml / 0.3 ml/min = 6.6min. 771mg / 6.6min = 1.9mg/sec).
First try: 30s * 2mg/sec = 60mg DMT-Fumerate (like vaping 50mg freebase DMT by 120% conversion rate)
Second try: 50s * 2mg/sec = 100mg DMT-Fumerate (like vaping 82mg freebase DMT by 120% conversion rate)
I made sure that the vaporization rate was not less than 0.3ml/min by weighting the solution after vaping: 1.90g, Prior vaping it was 2ml (= 2g) + 771mg = 2.77g. Vaped: 2.77 - 1.90 = 0.85g. 850mg @ 28% = 238mg DMT-Fum. 283mg / (30s + 50s) = 3mg/sec. That's 1mg/sec more than calculated. Unfortunately I only measured the water by volume prior vaping instead of weighting the solution. Point is, the actual vaping rate was between 2mg and 3mg/sec (definitely not less than 2mg/sec). Meaning: sufficient vapor was produced, sufficient DMT was transported into the lungs. Problem is that the DMT dosage was very large for to the effect felt.
I suspect the inefficiency to occur due to droplets condensing in the mouth, throat and upper lungs area. Places where they don't enter the blood stream.
Another theory could be that DMT-Fumerate (in water droplets) is not a potent way to "vape" and that freebase DMT works better. The use of FB DMT can be tested: dissolve 800mg DMT in 0.8ml PG, and dissolve that in 1.2ml water. Not sure if the PG turns to mist as efficient as water, due to higher viscosity etc. Even if it does, in theory FB could be just as ineffective if most of it settles prior reaching the lungs.
One more thing to test can be nebulizing harmala salts. Maybe the drops which land in the mouth enter sublingually and the drops in the throat get swallowed and activated orally. And everything which does make the lungs of course through there. Not sure about the advatage over sublingual harmalas though.
For now I consider the nebulizing DMT vape myth busted.
But just to be sure, someone other than some one with different DMT-Fumerate and a different nebu should try as well.
I suppose it is too late for you to see this, but did you ever try the other settings on your Omron A3? Was there anything exhaled while you tested the smallest drop setting?
The reliable characterization of particle size distribution and nicotine delivery emitted by electronic cigarettes (ECs) is a critical issue in their design. Indeed, a better understanding of how nicotine is delivered as an aerosol with an appropriate aerodynamic size is a necessary step toward...
www.nature.com
Studies have shown that drops can be too fine. Fine drops have an advantage of getting deeper into the lungs, but are also less likely to condense in the lung before being exhaled. DMT users are well trained to hold the hit in, which would help, but it's possible you were exhaling more DMT than if you had used a setting with bigger droplets. In addition to a higher mg/sec rate from bigger droplets, they're more likely to condense and sediment, so at least they don't get exhaled.
If you collected the nebulized aerosol in a bag like Volcano vapors, it might work better to inhale a full breath as quickly as possible, to jet the larger droplets deeper into the lungs than they might have gone from a gentle inhalation. A more forceful transition of air might help the droplets collide with each other too, causing them to sediment during the hold.
I imagine aerosols behave differently depending on their polarity. Water based solutions might be more likely to deposit sooner, being more compatible with tissues I assume. VS non-polar aerosols maybe getting bounced off wetter surfaces. Inhaling substances in freebase form seems to be very effective, perhaps because the molecules are getting deeper than polar aerosols, droplet sizes being equal.
I think someone will find a way to combine the micro-mesh and ultrasonic technologies in the nebulizer, with the convection heating and forced airstream from the volcano, to directly liquify and nebulize the freebase. That's what I want, ultra-fine drops of pure liquid DMT. A one breath deal.
But I can pretty much already do that out of the Volcano. And I recently vaped some DMT benzoate salt straight out of my volcano and it was very effective. So I don't really need a nebulizer to solve the alkaline bite of the freebase, and with dry vaping the salt there are no concerns that come with inhaling aqueous solutions. I suddenly forget why I became curious about nebulizers.
