If I had to pick one single substance as my favorite it would have to be smoked DMT, but my favorite entheogenic experiences lie in the synergistic combinations. I can't decide which one I like more: LSD + smoked DMT or Oral DMT + smoked DMT.
I guess I'll start saying why I picked DMT as my singular favorite. It has simply taken me to places and granted me certain abilities that no other entheogen on its own has done for me. It seems to have the strongest prevalence of what I refer to as "significant hallucinations". This isn't to say that other kinds of hallucinations might not even be more important, but to me, significant hallucinations are those which represent something in the real world such as a horse or the human figure or a bedroom with toys on the floor and books on the bookcase. Even though they still seem to be made of energy and light, they still seem to be highly representative. With smoked DMT, you don't have to sign up for the long haul (even though many times I would like to), and it can be a rather quick and effective way of hitting the reset button. I'm sure I'm leaving many reasons out, but let's move on.
Smoking DMT at the peak of an LSD experience results in the following qualities of experience for me: angelic, celestial, heavenly, loving, pure, magical, sacred and intrinsically detailed. For me, the LSD experience comes with many bumps in the road, and DMT smooths these out like it's nobody's business. All the body load, odd feelings, back pain just fade away for a few minutes (about as long as a normal DMT trip) as I'm swept away into beautiful celestial landscapes, but even though the experiences can have a very deep profundity about them, I'm allowed the opportunity of being a joyous observer with no fear or negativity of any kind that might accompany either DMT or LSD when taken by themselves. It can be such a soul cleanser that if I had the balls to take MAOIs, take LSD and then smoke DMT so that the DMT experience would last longer and there would be all kinds of synergy, that I can only long to imagine what kind of experience that might result in (and perhaps, I'll gather the cojones to do just that since I haven't really felt much fear before going into an experience in a while, and it just so much intrigues me). Unfortunately, as the DMT effects wear off right on time, I can feel the body load and little nooks and crannies of the LSD trip creep back in as the experience is "dulled" down to wherever I left off from before smoking the DMT.
Now oral DMT + smoked DMT is a completely different animal. It's physically incapacitating in the same way shooting a small man in the ass with elephant tranquilizer probably would be yet as mentally and spiritually stimulating as much as I don't believe a comparison exists that can be made to accurately reflect just how grand and magnificent the experience can really be. It may not always be the easiest experience, but it's brought about "long-lasting" euphoria magnitudes beyond what I've thought were possible within the human capacity (even with drugs or religious ecstasy). From a white light experience encounter with the godhead to the inside of elfin factories to Egyptian pyramid societies to rapture in golden holographic honey combs, this combination easily takes me further than anything or any other combination of things, hands down. When you can overload your system with that much DMT, ineffable and seemingly impossible things can take place, even by my frequent DMT smoker standards allow. Both a pro and con of this setup for me is that the first set of hits are easily enough to have me running for the bathroom for some of the most gut wrenching pukes of my life. This is quite difficult being as I mentioned the physically incapacitating qualities of the experience sort of make it difficult to get up and move (but luckily I've always made it, if only by half a step), but on the bright side, usually after this puke whether I've puked before or not, is enough to rid myself of the nausea for the duration of the trip because this purge is usually the mother of all mothers where virtually nothing can be left in the digestive tract to make one nauseous. From there out, smoking more DMT throughout the rest of the MAO inhibition is usually smoother with no nausea complications of any kind. Obviously the long duration allows for better integration with greater memory recall and a greater window of time with which to experiment with open-eyed energies and music and whatever it is from the experience I'm trying to explore.
Mushrooms I would love if they had a shorter duration and I could do them more often. Same with Ayahuasca. It's changa that I've been really enjoying lately, which is again, much shorter in duration than aya. Makes it easier for me to work with it more often.
