-Comprehensive 2C-E Dosages (self-made anecdotal reports)-
I have tried 2C-E at least 30+ times at many different dosages and have seen many people try it (this is one of the few chemicals I've had extensive interaction with, not in a bragging manner at all though). Oral is the "standard" trip level while insufflation and rectal administration provide experiences twice as strong due to bypassing first pass metabolism. Out of the 2C-X's known, 2C-E seems to be the third "softest/calmest trip" 2C-X, with 2C-B coming in second and 2C-C coming in first for "sofest/calmest trip" (this is based on anecdotal reports). Do NOT use my dosages as firm evidence in trying a first dosage. In my experience, most people trip very well and hard at 10mg, but there have been a small number of people with unusual effects like DMT-like visuals or opiate-like effects.
Oral dosages (simply divide by 2 for insufflated dosages):
1-2mg: Subtle stimulation and brightening of colors
3-8mg: A very light 2C trip. Vaguely noticeable visual distortions, only detectable when one focuses. Mental shifts are apparent but do not interfere with socializing, they simply make aspects of the world seem different or more interesting. Stimulation is present but does not significantly hamper the experience, though every person I have seen try it reports different effects for different people.
8-15mg (10mg is a good dosage for first timers): Medium/moderate/common trip. Visuals are apparent regardless of choice but do not interfere with ability to do physical/mental work; many say that the visuals are of a more "digital" nature. Mental shifts are undoubtedly apparent and many compare the effects to a mixture between Ecstasy and LSD. There is an inner body feeling described by many as "neutral" or "cold", rarely has a descriptor of "warmness" been attributed to the feeling. Stimulation is strong and the experience induces a state of bliss/awe for the experienced user.
15-30mg: Strong trip. There is no turning back at this point and one is completely immersed within the trip. Strong tracer/kaleidoscopic/geometric visuals present and a very mind-warping perspective is entered. This can (and has) produce +++ and ++++ experiences for many people. Do not try this dosage unless one has a tolerance for 2C-E or is already experienced with it. Stimulation is very apparent and usually interferes with users ability to stay still when in a calm environment but not always. Sociability is not hindered but some users may find it difficult to communicate with others who are not tripping, though not always the case.
30+mg: This is a dangerously high dose for an inexperienced user. Visuals are unavoidable such as 2-foot long trails, shifting objects, and unavoidable kaleidoscopic patterns. Stimulation can be too much for many users and cause interference with a trip. The maximum dosage tried has been 50mg and this only induced a ++ state but environment an mindset greatly affected this. Set and setting are an extremely important factor at this kind of dosage.
~~Synergies with other chemicals (not all people react the same, but this is the general consensus)~~
-Marijuana: Helps to calm the user and reduce the sometimes overbearing stimulation present. Also creates a more "flowing" feel to the trip and tones down the intensity of the trip while simultaneous increasing visuals.
-4-Aco-DMT: Only tried once, mixing a tryptamine and phenethylamine tend to create an odd synergy where the "neutral/coldness" feeling is cancelled out by the tryptamine. While I wouldn't say that they necessarily compliment each other, they can do so and this mixture is completely dependent on the user.
-MXE: I speculate that because 2C-E is an outwards/sociable trip and MXE is a self-contained/inner self trip, they would create an odd synergy. Unfortunately, the few people I know who have tried this mix were not of the most educated background and could only say "I'm tripping balls man". From only one personal experience with this, I say they compliment each other greatly although one experience isn't enough to make a definitive statement.
-MDMA: Based on other people's reports. The synergy between these two is spectacular and produces profound states of bliss and euphoria. Highly recommended for the common MDMA user.
-MDPV: Based on other people's reports. Of the few people who tried this mix, all have said that it increased their energy and added a slight euphoria to the mix. Overall rated as a nice addition but not in any way necessary. Be careful as MDPV and 2C-E are stimulating and can cause overstimulation for some.
This is a summary of the experiences I have seen or seen others have.