i don't know anything about vitamin K2
but theres a lot of info on flouride and the pineal
here ..they found it impacted its functioning in animals, i don't know of any human studies, although i haven't scoured that site thoroughly..
i also remember some study which found that in towns with a higher concentration of flouride in the water the kids tended to have much lower IQ's than those who lived in towns with lower amounts of flouride, and those with least amount of flouride had the highest IQ's, iirc. I cant find the link atm
Also- one from the site i linked says the pineal has the highest calcium concentration in the body. i didn't know this?:
"It is remarkable that the pineal gland has never been analysed separately for F because it has several features which suggest that it could accumulate F.
It has the highest calcium concentration of any normal soft tissue in the body because it calcifies physiologically in the form of hydroxyapatite (HA). It has a high metabolic activity coupled with a very profuse blood supply: two factors favouring the deposition of F in mineralizing tissues. The fact that the pineal is outside the blood-brain barrier suggests that pineal HA could sequester F from the bloodstream if it has the same strong affinity for F as HA in the other mineralizing tissues. The intensity of the toxic effects of most drugs depends upon their concentration at the site of action. The mineralizing tissues (bone and teeth) accumulate high concentrations of F and are the first to show toxic reactions to F. Hence, their reactions to F have been especially well studied. If F accumulates in the pineal gland, then this points to a gap in our knowledge about whether or not F affects pineal physiology. It was the lack of knowledge in this area that prompted my study."
SOURCE: Luke J. (1997). The Effect of Fluoride on the Physiology of the Pineal Gland. Ph.D. Thesis. University of Surrey, Guildford. p. 1-2."