Anyone Else Tried 25B-NBOME?

[Neon Aurora]

I'm pretty new here, actually just got accepted as a full member and I wanted to spark up a conversation of 25B, which I find fascinating.

I just tried 25B on Saturday, and it was great!

My friend acquired 50 mg of 25B-NBOME and(because we introduced him to the NBOMEs) he wanted to try it for the first time with us and he needed our help mixing it into a proper solution. So we mixed it using a ratio of 5 mg 25B/1 ml DI water and then 2% of the solution is 70% isopropyl alcohol to keep it sterile. This solution has always been great for 25C so we thought it would work for 25B as well, and we were right.

We dosed intranasally using an oral syringe with a micro-pipette tip on the end.

We consider one hit to be 500 micrograms, but we usually dose 250 at a time. Instead, since we lacked exprience with this compound and had read it's much more powerful, we started with a quarter(125 micrograms). This felt considerably stronger than 25c, but not too much different. It just felt like a stronger version. Over the course of the the next hour we took another quarter and felt its effects more strongly.

After the peak had worn off, we decided to dose 250 at a time. The first one provided a headspace change and mild visuals. I noticed cooler colors stood out a lot like blue and green while on 25C, warmer colors stood out, like orange and pink. After that dose had acclimated, we took another 250. This one threw me for a loop. It took affect quickly, and my vision was completely filled with beautiful fractals. They were so clear and had sharp edges. I could see them so clearly, I could probably draw each one of them. I'd never experience this clear open eye visuals. I could barely see because of how many fractals there were. I could also almost see the air, almost like I could see a field of energy rippling and interacting with itself.

I also noticed a kind of MDMA like feeling. Very euphoric and giggly. I also noticed a calmer, more mellow mindstate than with 25C. I felt like I could keep my thoughts together and it was an overall more structured experience.

After a while, it wore off and I attempted to go to sleep. Nope. I didn't sleep at all that night and neither did my friends. This leads me to believe the insomnia factor is significantly increased with 25B than with 25C.

Anyways, just wondering if anyone else had experiences to share or anything to say?

 

[DeMenTed]

25-c is more potent by weight than 25-b, you got it the wrong way round.

A typical dose of 25-b is 1mg and a dose of 25-c is around 400ug making 25-c stronger.

I agree though 25-b is a lovely chem

 

[Neon Aurora]

Perhaps potency isn't the correct term, but I looked at some brain scans showing absorbtion rate and 25B definitely had a much faster absorbtion rate.

Also, I beg to differ that common dosage for 25B is 1 mg. 500 micrograms of 25B was significantly stronger than 500 micrograms of 25C. I got up to about 750 micrograms and that was more than enough for me.

Maybe sublingually 1 mg would be sufficiant but not intranasally

 

[DeMenTed]

Tbh i didn't rate 25-c as highly as 25-b but it could have been down to tolerance in my case. I dosed my blotters bucally but i would like to try nasal route sometime as ive read it's a much more efficient roa.

My personal fav NBOMe is 25-I have you tried that one?

You may be right about 25-b being stronger. I'm going by how blotters are usually dosed and for whatever reason the 25-b blotters always seem to be higher dosed than the 25-c ones mmm strange

 

[Neon Aurora]

Ah, yeah, I'm sure using it on a blotter is different than the way that I dose it.

I haven't tried 25I yet, but it's in my near future(possibly this weekend or the next). I'm a little bit iffy on it, actually. The brain scans showed that 25I has an absorption rate lower than both 25B and 25C, and I've also read that it's a bit more "speedy" than 25C or B. I'm not a huge fan of the physical stimulation of the NBOMEs, but it's not a big deal. I wonder, is the physical stimulation less on blotter or about the same? I've only ever dosed intranasally. It's always worked so well for me that I never bothered with any other ROA.

 

[Dr_Sister]

Sister is a big fan of 25B both bucally and vaporized. Typical bucal dose is 1000ug, but 500ug is also quite pleasant.

Vapourized freebase is a different story altogether

200ugs - nice euphoria, mild morphing
400ugs - the lift off is pronounced, moderate visuals (some friends (50%) dosing 400ugs have been somewhat overwhelmed initially but leveling off 0.5 hrs into trip
600ugs -very strong onset that is somewhat uncomfortable but levels off 0.5 hrs into it, visuals pronounced, some tremors initially, visuals over in 1.5 hrs
800ugs - completely overwhelming, go blind from visualls initially, unable to function for 1 hour, visuals still very pronounced at 3hr mark but fading at 4hr mark, some tremors initially, too much.

 

[Jorkest]

you use IPA!??! and SNORT it!?!?! why would you do that...you should use saline...

 

[The Day Tripper]

yeah, wash your mister with etoh or an alcohol, rinse with saline, and mix with 10% xylitol (good for your schnozz & antimicrobial/does a good job at killing streph in your nose). It dissolved well enough for me that 2-3 sprays of ~.125ml each was more than enough with 25b. Solution was dosed @250ug/spray, or 2mg/ml. Never had any issues with that solution kept in a drybox (still in there).

No bacterial growth or signs of contamination.

 

[AluminumFoilRobots]

Thanks for the information about the xylitol, never knew that. Could be a general antimicrobial for brews and whatnot?

Man, I would at least use ethanol over isopropyl.

 

[TOXSIN]

I thought iso was bad even to ingest in single drops? you take that shit internally even at a 2% ration that sounds bad. Is 25B as potent as 25I? I am waiting to try this currently and heard its active in MICROGRAM units like 100-200Mic threshold effects so solution has to be like 1 MG/1 ML to make sure you don't OD.

 

[The Day Tripper]

I thought iso was bad even to ingest in single drops? you take that shit internally even at a 2% ration that sounds bad. Is 25B as potent as 25I? I am waiting to try this currently and heard its active in MICROGRAM units like 100-200Mic threshold effects so solution has to be like 1 MG/1 ML to make sure you don't OD.

I think your thinking of meoh, or methanol.

That stuff is nasty when ingested. Iso gets into your body via topical application, and is far less toxic than methanol. A few drops wont hurt. A few ml's wont kill. But don't take that as a validation of its safety. Use etoh whenever you have the option between the three. Iso, if necessary in sub ml amounts, methanol under NO circumstances.

And yeah, 25b/25i seem to be the most potent out of the ones I've tried (b,d,c,i; 25x's of course). Definitely one to handle with care, and stay under 500ug your first time, 250ug ideally to get a taste first. Its quite potent, and both 25i/b become uncomfortable to me over 750ug, 25c/d not as much. And in retrospect, i think I'd mix my solution at 100ug (or less) per spray next time.

Which brings me to another good point. Knowing your misters discharge volume per spray, to an approx degree of course. Always, always, put 1000mg of distilled water in your mister, or an even gram amount of water, then prime the mister, note the weight, spray one full spray 3 times, and weigh it again. Alternatively, prime the mister, then add exactly 1000mg of distilled water to your mister, rather than some odd # in the 800-900mg amount and subtracting off that. Makes the math a bit easier.

Divide the weight loss by 3, and you will get a mg amount of water per spray on average. Since water's density is 1ml/g we know how many microliters (1000ths of a milliliter, or ul) were discharged per spray. For one of my misters it was ~125ul of distilled water. Every sprayer will most likely be different, and each spray could vary by as much as 50%, so DO NOT make strong solutions for nasal mister administration with the nbome series under any circumstances.

IF you don't believe me, take your mister, tare it on your mg scale, spray it once. Weigh the loss and note it. Do this 9 more times and average the variation of weight loss per spray. You'd be surprised how much it can be over/under the average for each recorded mg amount lost per spray.

The only exception, would be if you were to use a dropper, and weigh how much mgs of solution were drawn up, then deliver it nasally that way. In that case, taring your scale, and knowing for example 100mg of solution was drawn up, and you have a 1mg/ml solution of X nbome, you can safely assume that will have 100ug of x nbome in it. Assuming your using only distilled water and a mg of x nbome per ml of solution. Add naoh or xylitol and that changes the density per ml, and you will need to adjust your ml/g density for the solution accordingly.

Use that value, to know what concentration to mix your solution at. But, if you use saline, or xylitol, be sure to measure the microliter discharge/mg solution discharge BEFORE you derive what mg amount of solution your mister puts out each spray, since adding nacl, or xylitol will change the density of the distilled water from simple 1g/ml for pure h20 to a different value for the solution of molecules.

And in the name of HR, i'd stay under 100ug of ANY nbome per spray when delivering via a nasal mister. Gives you wiggle room since each spray wont be exactly the same amount, and make an accidental overdose less likely to happen.

For example, you could smack the sprayer out of your irresponsible friends hand after the 4th spray and he would be fine, if you had it mixed at 250ug+ per spray that may not be so. Even for personal use, its wise to make it as hard as possible to overdose on nbomes by making diluted solutions.

I'd aim for at least 3 sprays for a light dose on any of the nbomes. You'll thank yourself someday in the event you overshoot your dosage, or worse provide a dangerously strong solution to a friend who may not know the danger a mere extra few sprays puts him/her in physically speaking.

Just imho some essential HR info regarding nasal administration of the nbome series, or any potent compound delivered nasally in solution.

If anyone needs clarification, feel free to pm and I'll explain it in less scientific lingo, or just post any questions.

You NEED to understand this stuff before attempting nasal administration of nbomes, its essential to safe usage of this potentially lethal series of compounds.

TLDR version-

Waters density is 1ml/g. Adding something like nacl, or xylitiol will change that.
You must know how many ul, or mg or solution were discharged per spray to know what concentration to mix your solution at. A bit of simple math could save your life or a friends life. If any of the above is confusing, ask for clarification before attempting nasal administration of the nbome series.

A nexian always does his research before he acts, and in this case its essential.