Athinyl and changa???

[chaoskontrol]

I’m currently taking a medical treatment but I’m not sure if it is compatible with harmalas.
I take Xanax, this one seems ok. But I take an other one called Athinyl, it’s miansérine. A sedative that acts as an anti depressive at 30mg, it helps me to sleep.
I asked the doctors but they were not able to tell me if it’s safe to take an MAOI with this.
I asked them if mianserine is a MAOI too thinking that it’s what i have to avoid, but I think that the right term is SSRI.
The doctor was just able to tell me that the Athinyl plays a role in serotonine level.
Can anybody help please?
Any natural alternative to these drugs maybe.
Changa helps a lot but i still have anxiety and sleep problems.

 

[chaoskontrol]

I have checked list 1 and 2 in the pinned post. I found no references about all that.
I don’t even know if my molecule is a SSRI.
It’s classed as: Other: Anti-depressive. Not just anti depressive it’s a bit weird to me.

 

[downwardsfromzero]

People should not take monoamine oxidase inhibitors and mianserin at the same time.

So, no changa for you. Also, the half-life is up to 61 hours so you really should wait at least 15 days after last use of mianserin before considering using MAOI substances.

Furthermore, if you have mental health issues powerful psychedelics might not be the best thing for you. They are not some kind of magic wand which fixes you just because you use them.

 

[Loveall]

According to this Mianserin is a tricyclic antidepressant. Apparently you don't even want to mix it with St John's Wort.

Features of serotonin toxicity may occur. These include CNS effects (including agitation or coma); autonomic instability (including hyperpyrexia); and neuromuscular excitability (including clonus and raised serum creatine kinase). This syndrome is more likely to occur if the patient has been exposed to two or more drugs that increase the effect of serotonin in serotonergic synapses (by increasing release, reducing reuptake or metabolism, or stimulating serotonin receptors), either as an acute overdose or if taken regularly, for example - SSRIs, MAOIs, tricyclic antidepressants, venlafaxine, tramadol, triptans, linezolid and St John's Wort, stimulant drugs of abuse (e.g. MDMA (ecstasy), amphetamines, cocaine, cathinone derivatives (mephedrone, etc).

The cardiovascular and CNS effects in overdose will be potentiated by simultaneous ingestion of alcohol, cardiovascular agents and other psychotropic drugs.

I feel like your doctor should have told you this, especially when you asked :shock:

 

[Doc Buxin]

According to this Mianserin is a tricyclic antidepressant. Apparently you don't even want to mix it with St John's Wort.

Features of serotonin toxicity may occur. These include CNS effects (including agitation or coma); autonomic instability (including hyperpyrexia); and neuromuscular excitability (including clonus and raised serum creatine kinase). This syndrome is more likely to occur if the patient has been exposed to two or more drugs that increase the effect of serotonin in serotonergic synapses (by increasing release, reducing reuptake or metabolism, or stimulating serotonin receptors), either as an acute overdose or if taken regularly, for example - SSRIs, MAOIs, tricyclic antidepressants, venlafaxine, tramadol, triptans, linezolid and St John's Wort, stimulant drugs of abuse (e.g. MDMA (ecstasy), amphetamines, cocaine, cathinone derivatives (mephedrone, etc).

The cardiovascular and CNS effects in overdose will be potentiated by simultaneous ingestion of alcohol, cardiovascular agents and other psychotropic drugs.

I feel like your doctor should have told you this, especially when you asked :shock:

Doctors don't know. You always want to ask a pharmacist these kinds of questions. The pharmacists are trained to know this kind of stuff, doctors are not.

 

[Loveall]

Yes, pharmacists are a great resource, but shouldn't the doctor also know about interactions? Maybe it depends on the country?

https://www.medicinenet.com/script/main/art.asp?articlekey=17046#

 

[chaoskontrol]

People should not take monoamine oxidase inhibitors and mianserin at the same time.

So, no changa for you. Also, the half-life is up to 61 hours so you really should wait at least 15 days after last use of mianserin before considering using MAOI substances.

Furthermore, if you have mental health issues powerful psychedelics might not be the best thing for you. They are not some kind of magic wand which fixes you just because you use them.

Thanks for clarification, i won’t take more mianserine.

I know what you mean about psychedelics, I consumed 200+ acids, a lot of K and 2CB, bromo dragonfly etc...
But spice helped a lot. I always feel better after and i can bring back things from these trips into hyperspace.
My depression was triggered by chronic pain a few months ago. I started spice let’s say a year before.
Everything goes better with it. My vision of life is way different and better now.
But thanks for the advice, I would not take some LSD now for exemple.

 

[chaoskontrol]

According to this Mianserin is a tricyclic antidepressant. Apparently you don't even want to mix it with St John's Wort.

Features of serotonin toxicity may occur. These include CNS effects (including agitation or coma); autonomic instability (including hyperpyrexia); and neuromuscular excitability (including clonus and raised serum creatine kinase). This syndrome is more likely to occur if the patient has been exposed to two or more drugs that increase the effect of serotonin in serotonergic synapses (by increasing release, reducing reuptake or metabolism, or stimulating serotonin receptors), either as an acute overdose or if taken regularly, for example - SSRIs, MAOIs, tricyclic antidepressants, venlafaxine, tramadol, triptans, linezolid and St John's Wort, stimulant drugs of abuse (e.g. MDMA (ecstasy), amphetamines, cocaine, cathinone derivatives (mephedrone, etc).

The cardiovascular and CNS effects in overdose will be potentiated by simultaneous ingestion of alcohol, cardiovascular agents and other psychotropic drugs.

I feel like your doctor should have told you this, especially when you asked :shock:

Wow!!!!!! Thanks for the link. I’m going to have to find something natural.

 

[chaoskontrol]

I’ll wait for 15 days and try a bit of caapi daily.
Do you have any caapi form to recommend for depression?
I have Muricata leaves.
Maybe X30 extract??