For me, I used to think that the same substances, no matter the route of ingestion, would produce the same effects.
But in my experience, the Changa Experience ≠ the vaporhuasca experience... Quite bizzare imho.
I find what hits me the most is just straight changa. There was some times where I did sublingual MOAI and then vaped and felt almost like NO effect from the DMT and thought I was locked out or something but a couple days later the changa hit me like a boulder.
But in my opinion the different routes of administration, including vaping after smoking an MAOI produce different trips/visuals. Of course it always seems like there's something new hiding up DMT's sleeve I'm no longer thinking that the ROA doesn't affect the experience.