it is nice and a has a very useful anmti-depressant glow to it, but I feel personally that mescaline(or at least the cacti) isnt good for me to dose often. I feel it to be taxing on the system and while the afterglow is amazing, I also feel burned out afterwords. Mescaline is amazing but for me personally I cant use it that way. I do feel its use is benificual though..it feels like a true tonic for my system, just not when I use it too often. There have been studies done on members of the native american church who use peyote regularily(not daily though I dont think) and they found only positive side effects I think.
Ayahuasca though I have been using daily for a few weeks now, sometimes 2 times a day. These are caapi only brews anywhere from a 1g microdose to like 20 or 40g..and then I usually drink a full dose with mimosa weekly as well..I dont feel any negative effects or get burned out feelings afterwords, ever. I feel more full of life and energy. It is a great antidepressant, not that I really feel depressed though. Ayahuasca is the only thing I can use this way, which makes me just want to focus on it even more. Mushrooms and cacti while amazing and great healers, both make me feel drained afterwords as well. I basically just lay there all tired the next day. I hate to say it, but even vaped DMT, to a lesser degree can make feel somewhat tired after sometimes compared to taking it orally in ayahuasca, I dont know why that is.