DMT negative effects?

[Existentialhero1]

Whats up nexus,

So i have done a good amount of research and have not really found any long term negative effects of DMT use. Maybe just a couple things here and there that pretty much all drugs are capable of doing. I am assuming however that any studies done on the effects of DMT were done on people who used DMT either in moderation or just once during the experiment. What, if any would be the negative effects of chronic DMT use, and how much would you have to use for those effects to take place. If all answers come back as still no negative effects then what if for some reason you did DMT like five-ten times a day. Thanks guys

 

[DoctorMantus]

Whats up nexus,

So i have done a good amount of research and have not really found any long term negative effects of DMT use. Maybe just a couple things here and there that pretty much all drugs are capable of doing. I am assuming however that any studies done on the effects of DMT were done on people who used DMT either in moderation or just once during the experiment. What, if any would be the negative effects of chronic DMT use, and how much would you have to use for those effects to take place. If all answers come back as still no negative effects then what if for some reason you did DMT like five-ten times a day. Thanks guys

Well since the brain is very fond of DMT if you didnt know, once entered into the brain it knows what it is, and what to do, that being why the duration is only about 15 mins. That being said it is very possible for it to take effects on the brain if used on an abusive level those i am not sure of though, it is possible you can get a brain aneurysm, or brain tumor these being really long term from maybe thinking too much, and i think if you were to do it five times a day then your tolerance would be pretty high and it would look as if you were just trying to get high and not looking at the importance's of of DMT and what you really should be focusing on. if i were you i wouldn't worry about negative effects and worry about the positive ones if you use it on a controlled and smart basis you shouldn't worry about that too much.

 

[Existentialhero1]

Thanks Doctor Mantus,

Im not planning on ever doing it more than twice a month i was just wondering. Are there any studies or incidences of dmt causing either and anurism or tumor?

 

[DoctorMantus]

That is good, that is a good gap, and i do not know of any studies and i do not think DMT has caused any aneurysms, or tumors, there would be a lot of other things that you would have to factor in, lifestyle, eating, and exercising, physical and mental health etc, etc, i do not think it should be your biggest concern.

 

[Entheojen]

I've been researching DMT about two years now and haven't heard about aneurisms or tumours. I guess there's the possibility of a stroke as your blood pressure rises too high, but I'm not sure what factors determine your risk of suffering a stroke over someone else.

Perhaps there is a more a psychological risk factor than a physical one.

 

[BananaForeskin]

^^

I agree with the above, extensive DMT use can certainly have psychological side effects.

 

[Existentialhero1]

I've been researching DMT about two years now and haven't heard about aneurisms or tumours. I guess there's the possibility of a stroke as your blood pressure rises too high, but I'm not sure what factors determine your risk of suffering a stroke over someone else.

Perhaps there is a more a psychological risk factor than a physical one.

When you say psychological side effects being caused by DMT, do you mean that the DMT changes the biological function/ chemistry of the brain as well as changing its form by say for example up regulation of certain receptors. Or do you mean psychological side effects like PTSD and HPPD that can be caused by any tramatic event like war, rape, gun to your head those things.

 

[Entheojen]

I meant more of a PTSD side effect from what you experience. But it could physically change the brain for all I know, but I haven't come across it yet in my research.

 

[Existentialhero1]

I meant more of a PTSD side effect from what you experience. But it could physically change the brain for all I know, but I haven't come across it yet in my research.

Thanks Entheojen thats what i was thinking you ment.

 

[Cosmic Rift]

I meant more of a PTSD side effect from what you experience. But it could physically change the brain for all I know, but I haven't come across it yet in my research.

I don't believe DMT can physically alter the brain. Although I do believe one can develop Hallucinogen Persisting Perception Disorder (HPPD) on DMT, just like with every other traditional psychedelic.

 

[burnt]

All psychedelics physically alter brain chemistry. However even after one dose of lsd there is a slight change of gene expression at least in rats or mice (forget the animal used). I think Dave Nichols group did a study on this. Its most likely transient though. Similar things probably occur with other psychedelics which may explain their tolerance.

 

[Newfound_wonder]

All psychedelics physically alter brain chemistry. However even after one dose of lsd there is a slight change of gene expression at least in rats or mice (forget the animal used). I think Dave Nichols group did a study on this. Its most likely transient though. Similar things probably occur with other psychedelics which may explain their tolerance.

Almost every experience in your life slightly affects gene expression. Eric Kandel claimed that if you remember anything about a lecture or a book then it means your brain is wired just a little bit differently than it was before exposure to the lecture or book. Anything that leaves a lasting impact on your mind is probably going to slightly alter gene expression. As far as negative effects go, my guess is that it would only take one wrong move with this powerful molecule to royally change your outlook on life. So be careful. Don't take what I say too seriously though, I'm just a factory peon.

By the way, whatever happened to Terence Mckenna?

 

[BananaForeskin]

^^^

He died

 

[burnt]

Almost every experience in your life slightly affects gene expression. Eric Kandel claimed that if you remember anything about a lecture or a book then it means your brain is wired just a little bit differently than it was before exposure to the lecture or book. Anything that leaves a lasting impact on your mind is probably going to slightly alter gene expression. As far as negative effects go, my guess is that it would only take one wrong move with this powerful molecule to royally change your outlook on life. So be careful. Don't take what I say too seriously though, I'm just a factory peon.

Yea exactly. Also saying changes gene expression doesn't really mean much until you understand what genes are being expressed more or less.

 

[Lavos]

Note that I'm still an inexperienced traveler, but, my philosophy, don't worry much about if you are changing your chemistry, focus more on discovering the self, and the possibilities.

 

[martiemcfry]

I think there might be some possible side-effects from smoking pure freebase dmt. I mean we don't know yet but it could be potentially as harmful as heroin or crack cocaine imo. Think about it, both opium and coca leaves have been used traditionally by ancient cultures for a long time, till dearly western civilization came around, purified and synthesized the straight active molecules, which will have very serious side effects if used chronically. Despite its similarity to brain chemistry is not safe to assume DMT its harmless, we dont know how is it with chronic/dependent use, cause fortunately we havent get to that point.

I don't think dmt is good by itself, its neutral. it could be mediated and pushed by those in power to create addiction and fragmented societies, like crack was in the 80s or heroin in the 40's, or it could be kept as something sacred, a grassroots practice to further strenght communities. There's a responsability on using dmt now, and having informed and active communities like this one to keep it away from people that just wants to get fucked up on something.

The popularization of dmt is something to be very wary of i think, this midas touch of our capitalist male-dominator western mode will take over if given the slightest chance.

 

[burnt]

^^^I completely disagree. DMT is not as addictive as drugs like crack or heroin. Most people don't like to do dmt often because its so intense. Its also not a "pleasure" drug meaning it doesn't just press your pleasure buttons and make you want more.

Furthermore there are societies that use dmt in plants on a regular basis. Purified dmt isn't going to case any more harm then dmt in plants EXCEPT if its smoked and it generates pyrolytic byproducts which usually are toxic. But thats a minor concern. I bet burning dmt creates indole and some free radicals but so does smoking anything.

But yes no one knows if there are any long term cognitive problems created by smoking dmt on a daily basis for years. I don't know any society that uses that much dmt. But I think there is a reason for that. DMT hammers you and you take a break.

 

[Autodidactic]

The only bad side effect that I've had or read about is probably DMT-fever, a few of us get it occasionally, I don't think anyone is sure what the cause of it is yet. You can read more about it by googling dmt-nexus and fever or coughing and headaches. For me it is basically waking up in the middle of the night, after having smoked dmt that day, dripping sweat but cold as hell, can't stop coughing and have the worst headache imaginable. I'm not sure if it is really DMT causing it or some impurity in the spice batch or what yet, but quite a few people have reported getting the same symptoms.

 

[Spicegnosis]

I posted in another thread,how I thought the flight or fight response was part of the DMT experience.

Could it be the cumulative build up of these improperly metabolised stress hormones,that leads to the DMT fever symptoms?

 

[martiemcfry]

DMT is not as addictive as drugs like crack or heroin. Most people don't like to do dmt often because its so intense. Its also not a "pleasure" drug meaning it doesn't just press your pleasure buttons and make you want more.

Yes, i didn't mean to say that DMT is the same as crack. Is quite the opposite imo and agree with you completely. But i think there's also a social context that gives meaning or dilutes the experience. The expansion of conciousness is not only an individual experience, but also a social phenomena that has developed through history. McKenna gives the example of how people in the middle age were amazed that St. Agustine could open a book, take a look at it for a while, and then tell people what it said on the book. And people were blown away by it! Aparently Agustine was a rare case in this period, cause he was the only one that could read in silence. Everybody else had to read aloud to read at all, it was simply part of how reading was conceived and it was very difficult for people to grasp any other way of doing it... our natural contemporary practice of reading in silence was not yet part of the collective conciousness of the period.

I think that the DMT experience is still a very novel experience for us, it has merely a few decades of underground use among a very select and hermetic community. Hyperspace will eventualy evolve, merge and change what we understand as reality as it becomes more and more part of our cotidianity, and there is a potential of abuse/addiction/trivialization on this. This is perhaps what is happening to marihuana on western culture. A sacred plant used for millenia for its mind-expanding properties is used as merely a commodity for a great percentage of the stoner culture. This is because is mediated by those who have power to implant a specific way of use, or living, a conscripted culture in which the rule is to fit in, and not to be yourself and find yourself throught building a relationship with the plant. I'm not saying that all marihuana use is meaningless nowadays, but i do see a sort of relative trivialization of this experience. The same thing can happen to DMT or anything else if is co-opted, labeled and packaged by capitalism. Ha i think i went a little off topic but just my two cents