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DMT Transdermal Administration

Migrated topic.
Is this like through the skin?

I once absorbed some spice on my index finger and it felt like I poked a hole through hyperspace and only my finger was there. It felt like it was glowing. That's all I know.
 
Look at this:


I wonder if sesame oil with a touch of limonene would work.

Sesame oil is used in Ayurveda as a carrier of medicines through the skin.

At worst, it wouldn't work and you'd have oil on your skin.

en.wikipedia.org

Sesame oil - Wikipedia

en.wikipedia.org en.wikipedia.org
 
It was freebase.
Might be interesting to rub some on the forehead...
but after my recent fuck up with harmaline war paint, I won't be trying it.
 
I am an avid sauna user and I was thinking that right after a good session, rub it right on!

We will see.
 
DMSO could possibly be used for trans dermal absorption but it is non selective, so any filth or metal particles or posions or whatever in the DMSO, the surface of your skin, your spice, and your container will go straight into your blood. So you have to be very careful. Swim doesn't want to imagine some shitty STB spice and all that lye and plant material going into his bloodstream.
 
There is a thread somewhere about this from a while back. There were several folks that tried different methods including DMSO with no success. Doesn't mean you won't succeed, but it might be worth a search to see what didn't work for others.

Pokey
 
blueskine said:
I am an avid sauna user and I was thinking that right after a good session, rub it right on!

We will see.
Click to expand...

Do let us know if works or not.


Freebase dmt should be soluble in sesame oil (should be; refer to Poorman's Tek in A/B forum)

+

Sesame oil "penetrates into the skin quickly and enters the blood stream through the capillaries."

+

Sesame oil has a long history of use in Ayurveda as a carrier of medicines into and through the skin.

=

This should work.....maybe.


Not sure where the best place to put it would be...Maybe around the throat glands, or the temples. Maybe it doesn't matter too much?
 
SWIM has read 2 or 3 separate threads stating that DMSO tinctures do not work with DMT. isn't DMSO just a faster method of trans-dermal?

SWIM doesn't think it would work with pure freebase, though maybe with N-oxides... hmmmm (puts it on his "to try list")

SWIM recently tested some sublingual administations
70mg sublingual very yellow N-oxide contaminated dmt crystals (dissolved in canola oil) with rue harmalas sublingually 20 minutes prior. Produced CEVs and OEVs
70mg sublingual white freebase (dissolved in canola oil) with rue harmalas sublingually 20 minutes prior. Produced barely any effects, no tracers, no CEVs or OEVs

SWIM will definitely try some N-oxides via DMSO, he'll try first with MAOI, then without if it works.

Speaking of transdermal, SWIM was recently wondering about application sights vs efficiancy.

One site said that armpit, penis/vagina, soles of feet were all good sights.
Would hands work as well, or at all? Seems easier. Or maybe belly button, that would be easy to hold a few milliliters...
 
q21q21 said:
One site said that armpit, penis/vagina, soles of feet were all good sights.
Would hands work as well, or at all? Seems easier. Or maybe belly button, that would be easy to hold a few milliliters...
Click to expand...

Soles of feet are good, but inconvenient...unless you don't plan on moving for a while.

Hands would be inconvenient, for obvious reasons.

It needs to be a body part that isn't going to be in contact with a bunch of things.

Scalp would be good if you're bald. Maybe forehead and temples. Neck?
 
It needs to spread out over as large a surface as possible so the bellybutton is out. Its usually applied to the abdomen/stomach area.

From the book Transdermal and topical drug delivery systems: "In general under the most ideal of circumstances only 1mg of drug can be delivered across 1cm2 area of skin in 24hrs" so so far swim thinks people have been covering far too small of an area. Keep in mind most patches are designed to deliver drugs like fentanyl in microgram doses, so 40+mg of DMT will require a lot of space but it should be possible.
 
mumbles said:
It needs to spread out over as large a surface as possible so the bellybutton is out. Its usually applied to the abdomen/stomach area.

From the book Transdermal and topical drug delivery systems: "In general under the most ideal of circumstances only 1mg of drug can be delivered across 1cm2 area of skin in 24hrs" so so far swim thinks people have been covering far too small of an area.
Click to expand...

Wow...50mg would cover a nice little patch of skin....even under the most ideal circumstances.
 
Sure would, but there are tricks out there they just need to be discovered. Like ethanol is used as a dermal penetration enhancer, and there are a heap of others. Its just a matter of gathering the ideas, making a list of what combos to try, and then running trials.
 
There is a tek where you can take the DMT acetate and make it a freebase, which, comes out like a honey after it is dehydrated.
Basicly mix...
DMT acetate
calcium hydroxide
dab of water
The add d-Limonene
at this point the DMT should be in the d-L
dehydrate d-L but not to the point of honey, it's still liquidy
mix that with ethanol (which a study online said d-L and ethanol worked together as a transdermal enhancer).
Cover chest as far as it will spread.

Any holes in that or evidence to support that?
 
blueskine said:
There is a tek where you can take the DMT acetate and make it a freebase, which, comes out like a honey after it is dehydrated.
Basicly mix...
DMT acetate
calcium hydroxide
dab of water
The add d-Limonene
at this point the DMT should be in the d-L
dehydrate d-L but not to the point of honey, it's still liquidy
mix that with ethanol (which a study online said d-L and ethanol worked together as a transdermal enhancer).
Cover chest as far as it will spread.

Any holes in that or evidence to support that?
Click to expand...
Purify everything and give it a shot. Swim has also read about limonene being a transdermal enhancer.
 
blueskine said:
There is a tek where you can take the DMT acetate and make it a freebase, which, comes out like a honey after it is dehydrated.
Basicly mix...
DMT acetate
calcium hydroxide
dab of water
The add d-Limonene
at this point the DMT should be in the d-L
dehydrate d-L but not to the point of honey, it's still liquidy
mix that with ethanol (which a study online said d-L and ethanol worked together as a transdermal enhancer).
Cover chest as far as it will spread.

Any holes in that or evidence to support that?
Click to expand...

Just be careful with the amount of limonene that is applied. It can be irritating to the skin....as in a burning sensation. Not fun.
 
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