Extraction of Angico stem bark

[modern]

So for the first attempt I did 25g of Yopo stem bark extracting with hcl then alkaline with lye and heptane pulls.

I tried to defat but just caused emulsions due to lots of saponins. Then shook the heptane and lost like 10-20% heptane as well.

I was expecting 10-100mg based on older reports found in simple tryptamines and paper I found but maybe got 1mg? This is Benzoate salt of whatever was pulled.

I was gonna try oral with maoi but may just try to do crude TLC since so little amount.

The correct species for 5meo should be Anadenanthera peregrina and others may just be weaker

Reattempting with 175g and slower and longer pulls. I’ll report back in a month or so when I finish up. Also whenever I get around to do my TLC

 

[modern]

So on the second attempt I added lye slowly and got ph 11-12. Rather than grey color that DMT bark gets I got a purple color. However after a day of gentle swirling when I salted it there was zero clouding. So I increased the ph again to 14 and the color became black. I added the heptane again and will attempt salting again…

So unless slight excess hcl and excess lye breakdown the 5meo this time I should get a measureable yield since used 175g starting material.

Next attempt I’ll use much lower hcl content or maybe another salt then try ph 11 again. To see if hcl is to blame. I used hcl first round but not prolonged time. Zero heat used.