The first and only time I tried to "candy flip," aka LSD + MDMA, the MDMA turned out to be meth (20 year old me, stupid stupid stupid). At the end of the trip I kept figuring out the meaning of life and forgetting it, to the point where eventually I realized I was simply cracked up from the drugs and went to bed.
I think this experience is a hallmark of doing drugs. Do any of them for long enough and you'll have everything in your life totally solved at some point while absolutely out of your gourd. And then you sober up and can't remember what the fuss was about to begin with. You consider that maybe the Chinese were on to something with wu wei, anyhow...