harmalas for daily use

[alkan0id]

Reifying.. such a great word, love it. I've never seen it used outside of computer science!

The main question I had forgotten to ask was do/did you combine the daily harmala regime with nootropics or any other enhancing drugs or plants. I personally am very wary of Noopept.. I was on it a few months ago, experimenting with doses ranging from 10-60mg a day, with only very subtle benefits at best, but definitely noticed the side-effects of short term memory loss and irritability. What worries me is that I've been off it for 2 months now but my short term memory has still been completely fucked recently, I will think to do something and completely forget it seconds later. This happens quite frequently. I'm not 100% sure that Noopept was the cause, but I have my suspicions. Also I found the withdrawal rather harsher than most people reported. I definitely developed a dependency on it.

Overall I'm tempted to start on it again, since I have now cycled off it more than the recommended 6 weeks every 3 months (it's something like that). I believe the need for cycling off has soemthing to do with it downregulating an enzyme called TrkB which has some role in the processing of tyrosine. Considering what a vitally important chemical tyrosine is in our bodies, this alarms me somewhat, too. Noopept is not a very thoroughly researched and tested chemical, and should be approached with caution.

Which adaptogens do you use with harmalas? The only ones I know of are ginseng and rhodiola rosea, neither of which I would ever consider mixing with an MAOI!

No doubt that as harmala is a good vasodilator and general blood mover, you will certainly experience major increases in this field too. But that I consider a total waste as the true powers arise with retention.

Yeah for me harmalas are a massive aphrodisiac. I can see what you're saying about the need for retention for the Sammadhi crown chakra stuff, but for me that is neither practical nor desirable. Maybe I will try to get into the super power stuff when I'm much older, but for the time being I'm a young man and I wish to make the most of my youth and virility while I still have it

I use full spectrum alkaloids as it makes zero sense for a man to leave aside the exceedingly profound effects of the other Rue alkaloids - see this thread for further info: https://www.dmt-nexus.me...spx?g=posts&t=15165

Yeah it was that thread that convinced me that full spectrum was the way to go. Seems silly not to take advantage of vasicine and vasicinone, as well as the lesser known harmalas: harmalol, norharmane, etc

* Dose high enough for entire visual field to become a single continuous tracer

Damn, that would be one insane dose! Easily north of 400mg for me. I think premature purging would be unavoidable in that instance. I'm not surprised it all got too much for you - there is no way I could dance for 24 hours solid, that's insane!! You must have been so far out. It's a shame institutions aren't open-minded enough to study this paranormal stuff you've figured out. Who knows how humanity could benefit?

Will try to give that Coulomb's Law stuff a look over when I'm more straight. Physics was never my strong suit at school, I usually turned up for lessons stoned and was more interested in my own spaced out thoughts than what the teacher was writing on the blackboard

 

[embracethevoid]

It's a shame institutions aren't open-minded enough to study this paranormal stuff you've figured out. Who knows how humanity could benefit?

Apparently they are!

Detection of extraordinary large bio-magnetic field strength from human hand during external Qi emission.
Seto A, Kusaka C, Nakazato S, Huang WR, Sato T, Hisamitsu T, Takeshige C.
Source

Department of Physiology, School of Medicine, Showa University, Tokyo, Japan.
Abstract

It is generally accepted that more than 10(-6) gauss order magnetism was not detected in normal human condition. However, we detected 10(-3) gauss (mGauss) order bio-magnetic field strength from the palm in special persons who emitted External Qi ("Chi" or "Ki"). This detection was possible by special arranged magnetic field detection system, consisted of a pair of 2 identical coils with 80,000 turns and a high sensitivity amplifier. Each of the coils were rolled 80,000 turns accurately, and were connected in series in opposite direction, actuating as a gradiometer.

We measure bio-magnetic field strength in 37 subjects with this detection system. The only 3 subjects of them exhibited strong bio-magnetic field of 2 to 4 mGauss in frequency range of 4 to 10 Hz. This magnetic field strength was greater than that of normal human bio-magnetism by 1,000 times at least. A simultaneous measurement of bio-magnetic field strength and its corresponding bio-electric current was examined in one subject. During exhibiting such strong bio-magnetism, its corresponding electric current was not detectable. Therefore, the extra-ordinary large bio-magnetic field strength can not derive from internal body current alone, hence the origin of the large bio-magnetism is still unknown. We suppose that the extraordinary large bio-magnetic field strength might be originated from "Qi" energy in the oriental medicine or in the oriental traditional philosophy.

Detection of extraordinary large bio-magnetic field strength from human hand during external Qi emission - PubMed

Will respond to the rest in due time

 

[John Smith]

Yeah for me harmalas are a massive aphrodisiac. I can see what you're saying about the need for retention for the Sammadhi crown chakra stuff, but for me that is neither practical nor desirable. Maybe I will try to get into the super power stuff when I'm much older, but for the time being I'm a young man and I wish to make the most of my youth and virility while I still have it

Are you sure you're taking enough ? When I get to the visual tracer stage it's almost impossible for me to get it up even if I wanted to.

Also, if you have a partner then sure thing, otherwise there are many reasons for abstinence besides mystical practices. Especially if you watch porn and whack-off daily, watch this Ted talk, it might change your mind.

[youtube]

Also, many groups are emerging who practice it, such as NoFap , with massive amounts of people reporting to reap the benefits.

 

[John Smith]

It's a shame institutions aren't open-minded enough to study this paranormal stuff you've figured out. Who knows how humanity could benefit?

There sure are. There was a beatiful document summarising the paranormal phenomena, on the accredited US university statistics page, no less. For some reason it has been taken down over a year ago, it is still viewable through archive, here you go:

AIR : An Assessment of the Evidence for Psychic Functioning : Jessica Utts (copy paste the adress without /anoniem tag if it doesnt work)

Most of the statistical stuff in the first part is digestible with undergrad statistics background(especially if you took a course on experimental design), and pretty interesting by itself. If not interested the juicy details are on the bottom.

Some cool ones:

Experiment 7: Remote Observation:

Purpose: It is often reported anecdotally that people know when they are being watched. Two experiments were conducted at SAIC to determine whether or not these anecdotes could be supported by a change in physiology when someone is being observed from a distance. The experimental design was essentially the same for the two experiments. This work was a conceptual replication of results reported by researchers in the Former Soviet Union (FSU), the United States and Scotland. The experiments in the FSU were interpreted to mean that the physiology of the recipient was being manipulated by the sender, an effect that if real could have frightening consequences


Method: The "observee" was seated in a room with a video camera focused on him or her, and with galvanic skin response measurements being recorded. In a distant room the "observer" attempted to influence the physiology of the observee at randomly spaced time intervals. During those time intervals, an image of the observee appeared on a computer monitor watched by the observer. During "control" periods, the video camera remained focused on the observee but the computer monitor did not display his or her image to the observer. There were 16 "influence" periods randomly interspersed with 16 "control" periods, each of 30 seconds, with blank periods of 0 to 5 seconds inserted to rule out patterns in physiology.

As preplanned, the results were combined, yielding an effect size of .39 (p = .005). As an interesting post hoc observation, it was noted that the effect was substantially stronger when the observer and observee were of opposite sexes than when they were of the same sex.

As a side note, a p-value of 0.05 or less is usually considered as statistically significant result.

Experiment 9: ERD AC Behavior:

Purpose: The remote viewing in this experiment was conducted in conjunction with measurement of brain waves using an EEG. The purpose of the experiment was to see whether or not EEG activity would change when the target the person was attempting to describe was briefly displayed on a computer monitor in a distant room. Details of the EEG portion will be explained as experiment 8. Here, we summarize the remote viewing part of the study.

Method: Three experienced remote viewers (#s 009, 372 and 389) participated. Because of the pilot nature of the experiment, the number of trials differed for each viewer based on availability, with viewers 009, 372 and 389 contributing 18, 24 and 28 trials, respectively. Although it is not good protocol to allow an unspecified number of trials, it does not appear that this problem can explain the results of this experiment.

Results: Responses were blind-judged using standard rank-order analysis. The effect sizes for the viewers 009, 372 and 389 were 0.432 (p = .033), 0.354 (p = .042) and 0.177 (p = .175), respectively. The overall effect size was 0.303 (p = 0.006).

Statistician Jessica Utts of the University of California Davis concluded:

"The statistical research of the studies we examined are far beyond what is expected by chance. Arguments that these results could be due to methodological flaws in the experiments are soundly refuted. Effects of similar magnitudes to those found in government-sponsored research...have been replicated at a number of laboratories across the world. such consistency cannot be readily explained by claims of flaws or fraud... It is recommend that future experiments focus on how to make it as useful as possible. There is little benefit to continuing experiments designed to offer proof."

 

[alkan0id]

Wow, that's fascinating. Would be nice if they carried out the whole experiment again with the same people but dosed with various doses of harmine/harmaline to see if there was a correlation between harmalas and this ability to exert magnetism.

I used to be very much into all this paranormal stuff and was an avid listener of Coast to Coast AM for years. The guests they had on made some outrageous claims, none of which I ever bothered to ratify or refute - I just kinda lost interest in that whole thing. But I do remember at least one show where the guest was talking about something like this - I'm not sure if it was exactly like this experiment though. I think it may have been about electric fields around the heart or something, rather an magnetism. I think this was the guy: Drunvalo Melchizedeck | Home Although being part of the whole "world is ending/changing for the better on Dec 21 2012" crowd, he has a lot to answer for imo.

I've been microdosing 100mg+ of rue harmalas every day for a few days now, and am now on day 2 of 30mg/day of Noopept. It has been a very rocky road, with whole days of utterly psychotic mood and suicidal moodswings, but the Noopept combined with the rapid onset of spring has begun to stablise that now. Tonight I had 10g of raw caapi powder because I ran out of rue extract, thinking it would be just a mild trip like the last time I dosed that much, but damn! It was easily as strong as 20g used to be. Microdosing potentiates macrodosing, I've read that on here more than once, and I can attest to its truth.

Strangest thing, that - I got more positive insight and direction from this casual (what I thought would be micro-) dose of caapi than I have from all the light-heavy macrodoses I've had this year combined. I think things are really starting to jel for me with ayahuasca.

Apologies for the length and garbledness of this post, I'm still coasting

 

[John Smith]

Yep, even better on small, non-visual dose with aya/pharma. Subjectively, there's some kind perceived 'telepathic' effect going on with more sensitive, or receptive people.


Also, embracethevoid, beautiful post. I've had something similar happen to me in the past, when I ended up with plenty of free time on my hands and lots of tryptamine curiosity. I basically drank somewhat low dose aya/pharma(but heavy on rue+cocoa) almost every night for over a month, with longest consecutive drinking interval of two weeks. Also smoked extracted harmalas in between. Anyway, I started to enter this blissful, meditative state when fully sober, and it got strong. I lost most the fear and inhibition, and every moment of waking existence felt great. State of mindfulness was effortless, at least 90% of waking time. I also completely lost sense of hunger but developed massive thirst during the day(when I didn't drink dmt). I think I ate an apple a day on average at most, some piracetam and just massively drank water. It's an extremely long and complicated story, I always wanted to write it as my intro essay but never get a chance to do that, I feel like I'd need several pages but still won't do it justice, and it may just sound crazy to most, even nexians.

Anyway to highlight main points I fully understand what you mean when people won't look you in the eye and this whole 'radiating energy' thing. Indeed, it felt powerful. I had a part-time job at a fast-food place while on a break from college and it was obvious from numerous interactions a day. Like girls for example would giggle almost at every mundane thing I'd say, and some guys would react really strangely. Like I'd be making a food item for a 'gangsta' looking guy and in the middle of it, I'd briefly look at him and he'd spit on the floor as a reaction. I wasn't messed up or anything, I'd never show up to work high or messed up. Only thing I did was smoke a bowl of harmala before work because it would intensify that overall feeling.

There were many other facets to the experience, when it deepened even more... Like synchronicites became so abundant it was like my whole life was being guided by it. Eventually, It got so powerful it got better of me...I couldn't handle it. I ended up being taken to the hospital by campus police after I stayed for over 2 days in student life centre sitting in the chair, and refusing to cooperate with people working there, and consecutively with campus cops themselves. Was an ugly sight, but they basically took me by force, injected me with something in the hospital and I woke up day later with a lumbar puncture lol(they thought I had some kind of brain infection/inflammation). Even after that I spent over several months in this state, just reverting to my old habits, like smoking cigs, and laying off the tryptamines. It faded.

One thing though you mentioned, there's definitely something about long-term abstinence and heavy tryptamine use. I'd be inclined to repeat the experiment in the the distant future and see if I can be smarter about it.

 

[embracethevoid]

Now I can respond to a little more...

Noopept is great at dosages between 0-30mg and 30mg is stretching it. Beyond 30mg you become slightly superhuman but also very cranked out, it rinses up choline and glutamate like no other it seems.


I've cycled off, it's funny you mention TrkB because I was pounding those receptors all month long, jacking up NGF & BDNF levels. Very fruitful, but one must cycle off the Pept for it to truly work magic. Harmala also hits the TrkB through some mechanism related to Kynurenic acid, it's a long story but harmala is the holy grail for the mental issues of today IMO.



As for what adaptogens I use: Reishi, Cordyceps, Gingko, Rhodiola, Ashwagandha, Gotu Kola, He Shou Wu (Fo Ti), Skullcap, and a myriad others; the list is extensive. Harmala is very safe as long as you ensure L-tyrosine/Tryamine levels are kept stable, the first sign of something wrong is a headache at which point you should stop all further intake of anything except for substances that break down tyramine. My diet is already 'dieta' to a good extent so living on harmala is easy. In fact, being on ayahuasca dieta is just truly having healthy eating habits in general anyway.




I do observe a long term tolerance or more appropriately, acclimatisation to harmala. Where once, 4g of rue tea would knock me to the floor and I would simply not be able to get up whatsoever, I am now drinking 10g as my morning cuppa when I feel like it's a Rue day. It still has the serious punch that a 10g tea should have but its gone from an intense sedative/purgative to a powerful stimulant/relaxant. I think once the sedation and purging have fulfilled their purpose of cleansing the body, the true effects of harmaloids come out in the name of Telepathine.


The other day I dosed something like 1.5-2g of Gibran tekked alkaloids over the course of a day, 300-400mg at a time with each dose 4 hrs apart. This dose would have killed me just a few years ago. I noticed a ceiling effect which is interesting. No matter how much I dosed, I wouldn't go further; it stopped just short of the rapture/entheogenic zone. The shimmers would start and I had iboga-like tracer effects but there was a general feeling of 'close but no cigar'. But I noticed that if I smoked some harmala, it would get me to the full visual tracer zone again.


Another thing I observe is that if I'm drinking microdoses of Caapi/Rue tea (5-10g per pint cup brewed repeatedly) then when I macrodose it's much much easier to get into the Rapture zone. When I stopped doing this, and tried to dose on extract alone, I found that I could not get into Rapture mode much if at all. Something tells me that THH, possibly generated via boiling is what causes the Rapture zone to have its really mystical effects.


So this leads me to believe that you are not just getting high on harmala alone, but you are actually getting high on serotonine/choline/dopamine too and probably a lot of pineal synthesised products. Some kind of downregulation/adaptation occurs to MAO-inhibition or something which makes sense to me as if a person is MAO-inhibited for a month straight, shouldn't they kinda... die? Hehe.




John Smith: It's great to hear that these effects are reproducible!
I'd love to hear your trip report! I rarely write reports myself to be honest, I guess I should get started. I'll tell you what you did wrong, I did it wrong too.

If you're throwing in Light-generating herbs into the mix such as shrooms, chacruna, mhrb, cacus, etc, then you have to cycle off the harmala for at least 3-4 days. When you feel the visuals have settled down and you have returned to sobriety from them, then you may continue with the harmala.



Otherwise the actives remain in your system and cause havoc. Not because they intrinsically cause havoc but because more Light in the brain causes all your thoughts to have more power. This means that if you have negative thoughts, evil thoughts, lustful thoughts, ignorant thoughts, they will get amplified heavily too and consequently you will spin into mania/psychosis.


If a person could keep a flawlessly pure mind, I have no doubt that they could probably trip on DMT, mescaline, LSD, for a year straight with no outwardly visible signs. But a single errant thought bounces around in the brain forever until it is purified by the being and thereby dampened. If it is not, then these thoughts embed themselves in the subconscious where they become thought-forms, and eventually they can become entire disease complexes like schizophrenia, alzheimers, parkinsons, tourettes, etc.

 

[AlbertKLloyd]

So this leads me to believe that you are not just getting high on harmala alone, but you are actually getting high on serotonine/choline/dopamine too and probably a lot of pineal synthesised products. Some kind of downregulation/adaptation occurs to MAO-inhibition or something which makes sense to me as if a person is MAO-inhibited for a month straight, shouldn't they kinda... die? Hehe.

There is so much worth discussing implied in this, but I need to ask, is there a formal thread to address harmala myths, claims and pharmacological data to have a detailed discussion about that topic alone?

If a person could keep a flawlessly pure mind, I have no doubt that they could probably trip on DMT, mescaline, LSD, for a year straight with no outwardly visible signs. But a single errant thought bounces around in the brain forever until it is purified by the being and thereby dampened. If it is not, then these thoughts embed themselves in the subconscious where they become thought-forms, and eventually they can become entire disease complexes like schizophrenia, alzheimers, parkinsons, tourettes, etc.

I am going to say this seems strange to me, those diseases can be caused by chemical changes, some of them can even caused on purpose with specific chemicals etc, the idea that they stem from errant thoughts that embed themselves. I am autistic and it is genetic in my family, we also have a history of Alzheimer's, facing these two challenges to my existence, or complications rather, make me cringe to read the idea that such things could be caused by errant thoughts.

There is evidence that sustained and constant hallucinogenic use can cause a lasting psychedelic state having the capacity to adversely affect functionality. I have heard of people having lasting effects spanning months to a year or more.

I wish this were not real:

Hallucinogen persisting perception disorder - Wikipedia

en.wikipedia.org

 

[embracethevoid]

So this leads me to believe that you are not just getting high on harmala alone, but you are actually getting high on serotonine/choline/dopamine too and probably a lot of pineal synthesised products. Some kind of downregulation/adaptation occurs to MAO-inhibition or something which makes sense to me as if a person is MAO-inhibited for a month straight, shouldn't they kinda... die? Hehe.

There is so much worth discussing implied in this, but I need to ask, is there a formal thread to address harmala myths, claims and pharmacological data to have a detailed discussion about that topic alone?

Funnily enough I haven't seen one AFAIK. I am still struck and amazed that a forum like the DMT-Nexus does not really give much justice to what is half the component of ayahuasca and assuredly a very intricate and subtlety-laden substance.

If a person could keep a flawlessly pure mind, I have no doubt that they could probably trip on DMT, mescaline, LSD, for a year straight with no outwardly visible signs. But a single errant thought bounces around in the brain forever until it is purified by the being and thereby dampened. If it is not, then these thoughts embed themselves in the subconscious where they become thought-forms, and eventually they can become entire disease complexes like schizophrenia, alzheimers, parkinsons, tourettes, etc.

I am going to say this seems strange to me, those diseases can be caused by chemical changes, some of them can even caused on purpose with specific chemicals etc, the idea that they stem from errant thoughts that embed themselves. I am autistic and it is genetic in my family, we also have a history of Alzheimer's, facing these two challenges to my existence, or complications rather, make me cringe to read the idea that such things could be caused by errant thoughts.

There is evidence that sustained and constant hallucinogenic use can cause a lasting psychedelic state having the capacity to adversely affect functionality. I have heard of people having lasting effects spanning months to a year or more.

I wish this were not real:

Hallucinogen persisting perception disorder - Wikipedia

en.wikipedia.org

[/quote]

I am not going to derail this thread; I will say that all of these diseases have a genetic component, an epigenetic component and a dietary component. All of these can be overriden to a maximal extent within the limits by control of the mind, as the brain is a computer and delivers electrical zaps to any given cell or DNA as necessary. Calculate the correct zap configuration and there is no reason why you would not be able to reverse anything not truly hard-coded.

All of these things are caused by hopelessness in some form or other. Sometimes it is an entire lineage which is diseased, it is not merely single beings who get disease. Not only are genes shared hereditarily but also, parasites, heavy metals, environmental poisons, dietary habits, thinking patterns, the entire works of life. So to ascribe these illnesses to merely genes is like saying that fingers cause bullets to kill people when you're missing the GUN! My family has a history of mental illness too and I had schizophrenia, key word: HAD. I also have HPPD but it does not bother me and I know many of these diseases can be directly induced by substances like MPPP. Either way, saying that diet cannot change a body is like saying bricks cannot repair a building...


So rest assured I have investigated this to quite a depth and breadth as my survival depended on it and interestingly, the culmination of my many years of research led to one thing: Harmala, lots of harmala

 

[alkan0id]

Are you sure you're taking enough ? When I get to the visual tracer stage it's almost impossible for me to get it up even if I wanted to.

I've yet to experiment with mega doses of harmalas and not sure I want to yet. I'm very new to the plant side of the psychedelic world, and the whole reason I'm in it to begin with is to attempt to heal my utterly crippling lifelong depression, hence my excitement when I found the threads on here about successfully healing severe depression with daily harmala dosing.

So I'm not sure what your definition of "enough" is in this context. Enough for personal exploration and soul searching? Yes. Enough for purge-your-guts-out transcendental visions and tracers? No - although I've had some pretty scary run-ins with Mimosa in that vein. Basically for me a typical harmala experience is characterised by an initial rush of sexual energy which is then masked to a greater or lesser extent as the intensity of the trip climbs, and/or the light kicks in. It is usually then that the experience becomes less body-focused and more cerebral. But yeah I would love to take this stuff with a chick - I think I would probably last for hours.

Especially if you watch porn and whack-off daily, watch this Ted talk, it might change your mind.

This video absolutely blew my mind. I also watched the longer 6-part video on his website. I had no idea I was a) addicted to pornography or b) that this could ever be a problem, until now. Wow. This might go some length toward explaining the depression but I doubt it's that simple. I'm definitely going to try abstaining from porn now. As for the NoFap movement, these guys have got to be clinically insane. 90 days, *ninety*? Jesus. In the interests of public safety, I wouldn't even consider attempting this, I don't even think it's natural, but I don't want to wander any further off topic

it [Noopept] rinses up choline and glutamate like no other it seems.

Does this mean that supplementing choline bitartrate is a must when on Noopept? I've read debate over its necessity/optimal dosage on nootropic forums concerning racetams in general, but not Noopept specifically. What would/do you do about glutamic acid depletion? I just happen to already supplement ~500mg L-glutamine 2-3 times a day, would this help? I might cut down to 20mg Noopept since yours is not the first wagging finger I've come across with regard to meeting or exceeding 30mg/day.

Harmala also hits the TrkB through some mechanism related to Kynurenic acid, it's a long story but harmala is the holy grail for the mental issues of today IMO.

I really hope you're right about that. I've learned more from you about harmalas in this thread than I have from the entire internet in the last 6 months. That you've singled out this of all the compounds to be of special importance is wonderful, considering how easy and safe it is to extract, and how cheap, available, and absolutely loaded with alkaloids the source material is. I'm really beginning to get my cold extraction tek down - I'm quietly confident I'll be able to get a 7% yield of full spec f/b from this one.

Where once, 4g of rue tea would knock me to the floor and I would simply not be able to get up whatsoever, I am now drinking 10g as my morning cuppa when I feel like it's a Rue day. It still has the serious punch that a 10g tea should have but its gone from an intense sedative/purgative to a powerful stimulant/relaxant.

I found myself to be quite a heavyweight with rue tea when first experimenting, although not even being in possession of scales at the time what looked like a whole lot of seeds was maybe only 2 or 3 grams. What I did find though more than once was that tea alone only had the slightest effect - I had to fish the wet swollen seeds out of the cup, and properly chew and swallow them. The first time I found some joy this way was very strange - the nature of the trip is not something I've been able to replicate since, at least not with my extractions.

I'm very very early in my experiments with extractions, but I suspect I might have to resort to just making a tea again to get the full, proper rue experience. Unsure why though, since all the actives should get pulled in a typical A/B extraction. Then the next time I tried this - tea, chew, swallow - nothing much happened, so I chased it all down with some dry, unchewed seeds and all that happened was that I got very ill - barely any psychedelic effects, just a few hours of nausea and gut trauma - way worse than anything I'd ever experienced from caapi.

I think once the sedation and purging have fulfilled their purpose of cleansing the body, the true effects of harmaloids come out in the name of Telepathine.

That's an excellent point - what else is purging than having the noob knocked out of you by the spirit council. So once all the parts of you that are incompatible with that higher realm have been cleansed/purged out, there is no reason left to be nauseous - you are initiated and ready for the higher powers and perceptions of Telepathine.

The other day I dosed something like 1.5-2g of Gibran tekked alkaloids over the course of a day, 300-400mg at a time with each dose 4 hrs apart.

Jesus! That's like 40g of rue's worth of harmalas. You've clearly learned how to Jimi this stuff

Not because they intrinsically cause havoc but because more Light in the brain causes all your thoughts to have more power. This means that if you have negative thoughts, evil thoughts, lustful thoughts, ignorant thoughts, they will get amplified heavily too and consequently you will spin into mania/psychosis.

But a single errant thought bounces around in the brain forever until it is purified by the being and thereby dampened. If it is not, then these thoughts embed themselves in the subconscious where they become thought-forms, and eventually they can become entire disease complexes like schizophrenia, alzheimers, parkinsons, tourettes, etc.

I think this might have been a major cause of my depression from my use of LSD, mushrooms and the like in my teens. I was very deeply spiritually attuned in those days and something about all the drugs fucked that up and put some very negative ideas and concepts in my subconcious that remain there to this day. Perhaps harmalas can release these, I don't know if anything can.

This is turning into one hell of a thread, any chance it can be stickied if it isn't already?

 

[embracethevoid]

I'm not sure what's going on nowadays. Yesterday I dropped 450mg of rue alkaloids. This felt identical in effect to around 4g of rue tea when I first started - just slightly past threshold effects. At a 5% alkaloid concentration assuming 70% pure extract, this dose is equivalent to 6g rue.


It seems there is some kind of long term acclimatisation going on when harmala is orally administered. Just a few months ago, 300mg would put practically knock me to sleep - full silver shimmeryness everywhere. Even stranger, I can load the same old dose into my glass vaporiser and it knocks me into space.



But it feels like I'm inhibited somewhat from getting into the "Superman zone". There is a very specific characteristic of that zone. It feels almost like you're getting pulled into a black hole of effortlessness, like you're constantly falling towards the path of least resistance.

I mean I feel the fluidity and even today I feel it, but I'm just not absorbed like how I used to be. However the other day I drank an unknown quantity of rue tea then dropped some alkaloids. I instantly dropped into the superhuman zone and dancing was very fluid, I could feel the energy rushing through my full body in total synchrony. This is before the 450mg dose of which was just yesterday.


I think that basically if you want to take harmalas into the 'superhuman' zone, you have to drink rue/caapi tea in microdoses every day and let it accumulate into your system, and turn your body into a home for the spirits of these plants, if that makes sense. That is to say you have to align your lifestyle into one where mother aya can really do her work unhindered, so no distractions, no silly video games, no junk food, etc, lots of meditation, as much fasting as possible, etc. Keep the mind on lock-down.


If i drop a large amount of extract, it doesn't really do much. I found that the magical effects truly arose when I drank 10-20g caapi tea every day, letting it accumulate over a few weeks. Then smoking/dropping harmala extract takes a person to space. As again... harmala potentiates harmala.




As for the Harmala-KYNA & mental illness connection, here's a paper describing KYNA's role:

Tryptophan–Kynurenine Metabolism as a Common Mediator of Genetic and Environmental Impacts in Major Depressive Disorder: The Serotonin Hypothesis Revisited 40 Years Later

The original 1969 Lancet paper proposed, “in depression the activity of liver tryptophan-pyrrolase is stimulated by raised blood corticosteroids levels, and metabolism of tryptophan is shunted away from serotonin production, and towards kynurenine ...

www.ncbi.nlm.nih.gov

Two showing norharman's role as a neuroprotectant, inhibiting quinolinic acid which is a toxic metabolite of KYNA:

Antibiotic-mediated release of tumour necrosis factor alpha and norharman in patients with hospital-acquired pneumonia and septic encephalopathy - PubMed

Patients with hospital-acquired pneumonia and septic encephalopathy had a significantly longer ICU stay with higher mortality rate compared to patients with hospital-acquired pneumonia alone. Antibiotic-mediated TNF-alpha release may induce the kynurenine pathway. TNF-alpha activates...

www.ncbi.nlm.nih.gov

Interferon-gamma-inducible kynurenines/pteridines inflammation cascade: implications for aging and aging-associated psychiatric and medical disorders

This review of literature and our data suggests that up-regulated production of interferon-gamma (IFNG) in periphery and brain triggers a merger of tryptophan (TRY)–kynurenine (KYN) and guanine–tetrahydrobiopterin (BH4) metabolic pathways ...

www.ncbi.nlm.nih.gov

Either way, I am very interested to know what's changed to my body. I am regularly ingesting doses now that before, I would have shat bricks at the faintest thought of. Way back I remember accidentally drinking like 6 or 7g rue tea. What followed was 6+ hours of almost crying in bed like a gibbering wreck just pleading with the universe to make it stop. Another time, a similar dose was ingested by a group of 5-6 people, myself included. We were all floored, and I mean FLOORED. Nobody could get up. It was tragicomical, so painful yet so hilarious. We were lying around groaning in agony but the atmosphere would be broken every few minutes, punctuated by laughter at the sheer absurdity of the situation we had found ourselves in.

But now? This dose doesn't make me bat an eyelid. I honestly feel a stronger effect from smoking a cigarette in the morning. At the same time it feels like a huge river rushing through my veins and I know that if I were to ingest some kind of synergiser like spice or MDMA, it would pretty much kill me.

Also, I was taking in copious amounts of COX-2 inhibitors back when I entered superman-mode and I had iboga metabolites in my system. I think that has a LOT to do with it actually. Will start experimenting again and report back some time.

 

[jamie]

"Yesterday I dropped 450mg of rue alkaloids. This felt identical in effect to around 4g of rue tea when I first started - just slightly past threshold effects."

Sounds like tolerance. Tolerance might build to the psychedelic effects with daily high doses, while MAO inhibition could still remain. This could be why some shamans drink daily and get used to the side effects of the harmalas but dont get any tolerance to the admixture.

All I know is that 450mg would have me absorbed in visions for hours with heavy tracers and ataxia and would last like 12+ hours. Though 4g of rue tea would also be pretty far past threshold effects for me..

I never experienced anything like that kind of resistance to the effects when I took daily microdoses for around 18 months..but I took like 5mg sublingual..or like .5g rue or maybe 5g caapi a day. I cant imagine how macrodosing daily would be useful for me.

Maybe take a break?

 

[embracethevoid]

Yeah I took a break. In fact I'm one month into the break or so. The heavy tracers have faded to a faint glimmer. They are still there, but they are beneath the surface now. As if the once rippling ocean has stilled. I'm guessing they have moved 'inward' into the realm of the third eye now as I still feel the meridians all day long on the days I have no harmala in the system whatsoever.

All I know is that 450mg would have me absorbed in visions for hours with heavy tracers and ataxia and would last like 12+ hours. Though 4g of rue tea would also be pretty far past threshold effects for me..

This was me barely two months ago. I've taken a break but it appears tolerance is long-term. Either that or THH is actually what's responsible for the more intense visual phenomena - I have mostly been playing with harmaline/harmine.


As for how macrodosing daily would be useful... It is medicine. Meditate the ataxia away, meditate the shakiness away, meditate the vulnerability away. This places you in a gamma brainwave state in waking life. It is absurdly easy to enter the Flow state like this. I feel very still these days. Unperturbable. Normally I am very reactive to the environment and small stressors to other people are large stressors to me. But now I feel like I could be skimmed by a fighter jet flying over my head at mach 6 and remain composed. 3 or 4 miles away with my head detached from my neck... but still composed. Shaken, but not stirred.

 

[SHroomtroll]

I really enjoyed this thread, ive been dosing about 100mg of crude harmalas a day for a week now.
Im really surprised how strong the effect is, esp in the evening when i add some cannabis to the mix.