Is mixing cacti resin with syrian rue safe?

[Ambrosaure]

Hi everyon,e I'm gonna soon have my first cacti experience!
I'm use to have to take unusual large dose (4 times "heroic dose" and I have to wait at least 6 weeks between trip) so I always take rue with my mushroom to potenciate. I was going to do the same with cacti but @blig-blug told me it could be not safe and to ask here. So here it is

Thank for any help

 

[blig-blug]

Yes, my concern is not about mescaline, but about the other stuff in the cactus resin. Does anybody have experience with this?

 

[Jamie01]

I would see how cacti effects you alone first.

Yea people combine them but I won’t say go do it.

 

[doubledog]

I hope you understand that we can not predict reaction of your body to the mix, but in general, it's reasonably safe.
Better question would be if it's worth to do it, I would say no, imo there is no such synergy as with harmala+tryptamines.

Some people like it, some not.

 

[blig-blug]

imo there is no such synergy as with harmala+tryptamines

Mescaline is not metabolized by MAO, so it makes sense. I'm personally interested in trying it.

@doubledog have you tried it with resin or some other kind of full spectrum cactus extract?

 

[doubledog]

Only with mescaline, never with the resin.

Maybe I could try it, just made some resin.

 

[Prima Materia]

Try the cactus only first few times and only then consider adding harmala. That is my advice.

 

[blig-blug]

Only with mescaline, never with the resin.

Maybe I could try it, just made some resin.

I'm concerned about the interactions with tyramine (there may be really a lot in a large dose, potentially much more than in any cheese) and some of the other stimulating alkaloids. I would be careful with the dose.

 

[Prima Materia]

I'm concerned about the interactions with tyramine (there may be really a lot in a large dose, potentially much more than in any cheese) and some of the other stimulating alkaloids. I would be careful with the dose.

Very good call. I agree.

The intense side effects I had had from cactus syrup alone were quite concerning. I do not imagine adding harmala to that honestly.

 

[blig-blug]

I think it could depend on the cactus. I would never try it with my current bridgesii batch, very stimulating and long lasting.

The best may be to try it with pure mescaline first, then with a low dose of resin. Still, if mixing it with full spectrum is untested territory I'm not sure I want to try it.

 

[bezevo]

come on .....at the worst you would only die !

No worries :0

 

[doubledog]

I'm concerned about the interactions with tyramine (there may be really a lot in a large dose, potentially much more than in any cheese) and some of the other stimulating alkaloids. I would be careful with the dose.

Yes, dose have to be very small as always with potentially dangerous combinations.

On the other side, I have combined harmalas with MDMA without any issues, so imo dangers of harmalas interactions are maybe not so high with careful dosing.

In my harmalas+mescaline experience, most pronounced or potentiated were mescaline's bodyload effects. I would maybe try to add harmalas later into experience, just at the peak or later.

 

[dithyramb]

This question comes up now and then. Here is my repeated answer. Some types of cactus seem to not give side effects, but some do. I felt a dangerous hypertension once and quit doing the combination after that. But in the end, it was a pointless combination imo, just my own attachment to rue coming in. Cactus by itself is better; there is no synergy.

 

[blig-blug]

Given that blood pressure monitors are very cheap nowadays, it could be a good idea to get one when experimenting with this kind of combinations.