ava69, thanks for your reply! I will go with your recommendation of 250 mg THH orally followed by DMT complexed to HPBCD. A few questions:
1) I have plenty of experience with mescaline and shrooms, including ludicrous heroic doses. But my only experience with DMT is some 12-15 mg vaping runs with the GVG or e-mesh. I haven't done Ayahuasca yet although I just acquired the caapi and chacruna. Was planning to start low with just caapi (no DMT) per ms_manic_minxx's recommendations. I have freebase DMT extracted from MHRB.
What's your recommendation for the amount of DMT to use for these initial (THH + DMT + HPBCD) trials? I have a trip sitter but I want this to be more in-control and self-guiding. Like a moderate shroom trip.
2) (2-Hydroxypropyl)-Beta-Cyclodextrin is easy to find online and commonly referred to as HPBCD. CAS #128446-35-5 with molecular formula C44H75O36.
Hydroxypropyl-Beta-Cyclodextrin is more difficult to locate with CAS #94035-02-6 with molecular formula C54H102O39.
Sometimes I see the (2-Hydroxpropyl)-BCD (CAS #128446-35-5) referred to as simply "Hydroxypropyl-Beta-Cyclodextrin (HPBCD)", even though it seems it should technically be referred to as (2-Hydroxypropyl)-BCD.
I noticed your container says Hydroxypropyl-Beta-Cyclodextrin, but I don't recognize the CAS #. It says "CODE #410-903"?
Did you specifically seek out the more difficult-to-find Hydroxypropyl-BCD (CAS #94035-02-6) rather than the more commonly available (2-Hydroxypropyl)-BCD (128446-35-5)?
3) Are you aware there are reports of HPBCD causing hearing loss? I'm trying to figure out whether the dosages and method of administration in these studies are relevant to our context.
Cyclodextrins are a family of cyclic oligosaccharides with widespread usage in medicine, industry and basic sciences owing to their ability to solubilize and stabilize guest compounds. In medicine, cyclodextrins primarily act as a complexing vehicle and ...
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