Psilocybin extraction

[Loveall]

Just spent my last couple of hours dissecting this post and it's all very intriguing! any updates?

We were able to get (nor)baeo to crash out from xylene after FASA. However psilocybin remains elusive.

There may be a way to get it, but the pH and salt concentration window may be narrow. In the pharmaceutical industry folks adjust these two parameters (along with temperature) to isolate temperamental stuff.

The search for a process window seems difficult if one is using bioassays or has to send out stuff for analysis each time.

Soooo we are working on a home raman spectrometer setup. If it works one can hopefully track where the psilocybin is real time as salt and pH are adjusted and find a good window where it will move out of water (crash out or go into a solvent).

There are a lot of challenges for this (for example, in a crude extract there will be a lot of Spectra overlapping making it too noisy), but we are going to try to proceed this way.

One simple option is to try a bufo-like extraction (base/dry/extract with IPA/FASI). Has anyone ever tried something like this?

 

[Loveall]

Expanding the suggestion above with some details:

Optional: Wash dry ground mushrooms with 99% IPA vitamin C (this won't pull actives). Dry.
Extract mushrooms with calcium hydroxide and a small amount of water (pH should be basic)
Decant/Filter
Dry and collect gunk
Extract with 99% IPA (if it works for bufo...)
FASI

 

[neb]

Amount shown vaporized had a similar disassociative feeling like ketamine, but for two hours. Only slight visual distortions with 'halos' or half circles moving different directions simultaneously just in peripheral vision. Not quite the desired effects but you have to start somewhere...

Well, I would say any effect is a sign of something magical happening hahaha

I would love to try this some time. I love ketamine :lol:

 

[starway6]

many years ago i remember smoking black opiated hash and taking an orange pill called.....
[ orange psilocybin ]an orange tablet ..i was in cartoon city for hours after that!

so i know it can be put into a pill...