Rumor that mg seeds are the most potent

[shilo]

[Mod edit: merged from other thread into this one, the original post was the one below by the Ugx alt account]

this was intense and the lingering wasn't gone until around 49 hours later.
4-7 seeds, spread them onto some parchment-paper.
fold it to get four Iayers of paper between the seeds and hammer.
put it on something hard and crush them up well.

add a shot or two of water to the powder.
use a vessel with minimal trapped air and freeze.
thaw and filter, squeezing as much liquid from the pulp as possible.
raise ph to 11 with K2CO3, swirl every now and then about two hours.

 

[shilo]

[Mod edit: merged from other thread into this one, the original post was the one below by the Ugx alt account]

You can also chew with a pinch of baking soda.

 

[Ugx]

After extensively researching I've come to this conclusion.

 

[Nydex]

Care to elaborate?

 

[Ugx]

The peak of LSH and tricolorin A is before fruit and seeds are formed.

 

[Transform]

The peak of LSH and tricolorin A is before fruit and seeds are formed.

Abstract

Tricolorin A, (11S)-11-hydroxyhexadecanoic acid 11-O-α-l- rhamnopyranosyl-(1→3)-O-α-l-{2-O-(2S-methylbutanoyl)-4-O-(2S-methylbutanoyl)}-rhamnopyranosyl-(1→2)-O-β-d-glucopyranosyl-(1→2)-β-fucopyranoside-(1,3′′-lactone), the major phytogrowth inhibitor isolated from Ipomoea tricolor Cav. (Convolvulaceae) was found to be a potent uncoupler (U50=0.33 μM) of photophosphorylation in spinach chloroplasts. Tricolorin A inhibited H+-uptake and adenosine 5′-triphosphate (ATP) synthesis, and stimulated basal and phosphorylating electron flows. Using a combination of two well-known fluorescent ΔpH probes, 9-aminoacridine and 9-amino-6-chloro-2-methoxyacridine, the uncoupling behavior of tricolorin A was also demonstrated for submitochondrial particles. Polarographic data showed that high concentrations (20 μM) of tricolorin A inhibited photosystem II (PSII) electron flow at the level of plastoquinone B (QB). Chlorophyll (Chl) a fluorescence analysis showed that tricolorin A induced accumulation of QA− and strongly decreased the electron transport capacity, suggesting that the target of this molecule was located at the QB level. The macrocyclic lactone-type structure of this allelopathic agent proved to be an important structural requirement for uncoupling activity since its hydrolysis caused loss of the inhibitory potential.

What are your thoughts on the value of tricolorin A in a human phytomedicinal context?

 

[Ugx]

What are your thoughts on the value of tricolorin A in a human phytomedicinal context?

It should be avoided sublingually

 

[TheGreenPhantom]

...so... make a tea from the buds?

 

[Ugx]

...so... make a tea from the buds?

I'm not experienced with them to be honest with you. If I had access I would either chew them as soon as harvested or a quick frozen tincture.

 

[Ugx]

scopoletin has come to my attention. It's basically the tricolorin of argyreia nervosa but it cannot be avoided sublingually. I can no longer advocate for the sublingual use of hbwr.

 

[secpropyl]

scopoletin has come to my attention.

Scopoletin has attracted the attention of medicinal chemists and health professionals because of its broad range of beneficial properties, such as antibacterial, antifungal, antiparasitic, anticancer, anti-inflammation, hepatoprotective, antihyperlipidemic, antidiabetic, neuroprotective, antioxidant, anti-angiogenesis, anti-hypertensive, analgesic, anxiolytic, immunomodulatory, anti-osteoporosis, anti-allergic, anti-aging, and anti-gout activities. In addition, scopoletin is an inhibitor of various enzymes, including choline acetyltransferase, acetylcholinesterase inhibitor (Rollinger et al., 2004; Hornick et al., 2011), aldose reductase (Lee et al., 2010),

https://doi.org/10.3389/fphar.2024.1268464

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The results indicate that its antidepressant-like effect is dependent on the serotonergic (5-HT(2A) receptors), noradrenergic (alpha(1)- and alpha(2)-adrenoceptors) and dopaminergic (dopamine D(1) and D(2) receptors) systems.

Redirecting

 

[blig-blug]

What's the purpose of this thread?

 

[Ugx]

Many stories about mg seeds. Scopoletin isn't the "tricolorin" of argyreia. These have high molecular weight. Best results I've had are chewing seeds a little while then spitting everything. The green herb is LSH-rich.

 

[Transform]

It should be avoided sublingually

Is that all? What's your reasoning behind this statement?

Since you've mentioned it, scopoletin is a coumarin derivative, and not an alkaloid at all, despite what its name may appear to suggest - there's no chemical relationship with either scopolamine or scopine - just for the record, and for the sake of clarification.

What's the purpose of this thread?

Indeed.

 

[Ugx]

To get peak LSH you will have peak tricolorin A. Tricolorin A has been used against cancer but it isn't selective. Even swishing it is cytotoxic. Hbwr has something similar called operculinic acid A. Operculinic acid A is basically the opposite when it comes to cytotoxicity.

 

[eLeSDee]

Can an Hbwr seed be used nasally? Like take the shell off and crush/grind to fine powder and snort?

I read somewhere it was effective, and would like to hear anyone's opinion or general help as I feel I should just chew it?, but want to get the most out of it without nausea cramps obviously at a minmum..

I was going to powder it theory chew up and let it sit in my mouth sublingually for 20-30mins.. is one seed definitely NOT even close to a trip? Maybe 2? please any help is appreciated!! I want to avoid extraction if possible.

 

[Ugx]

Everything about HWBR is perfectly engineered to be used buccaly.

 

[eLeSDee]

Awesome! Thanks Ugx..bucally for about 30mins and then spit it out to avoid nausea? I think I heard this is how I could utilize heavenly blue mg as well, or is this conflicting with another or is this just a myth?

I am about to try one or two seeds of my Hbwr I am just hoping it is worth it and honestly, to avoid nasty side effects.

I hope pepto can handle the bis

 

[Ugx]

HBWR doesn't have tricolorin A.

 

[Transform]

Operculinic acid A is basically the opposite when it comes to cytotoxicity.

What, it can bring dead skin cells back to life? This could be the beginning of a wonderful cosmetics line