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Sassafras.. Cinnamolaurine

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T

Tinc

Rising Star
Namaste! Long time lurker, first time poster. I have a question for the community.
Has anyone had suscess with a extract from sassafras? There is a small amount of info I can find about Cinnamolaurine, the proposed active compound in sassafras, but not a lot . Has anyone had suscess with a cwe? Or the food grade alcohol extraction that's out there?
I believe the spirt of this plant has a lot to offer us in healing ourselves, most of which is destroyed when it's taken and used for the production of mda or Mdma.
Can anyone offer advice on a shamanistic extract of sassafras? Thank you all! Love & light
 
"I believe the spirt of this plant has a lot to offer us in healing ourselves, most of which is destroyed when it's taken and used for the production of mda or Mdma."

Why do you say that? MDMA presents a vast improvement of the therapeutic potential of natural precurser plants like sasafras in my opinion. I don't hear many interesting things about sassafras.
 
I agree that mda & mdma have therapeutic potential, as much research has gone into this. Maps has a wealth of information on positive results using these Empathogens. I believe as well as they work they are only a fraction of the entire experience possible. Much like the cocoa spirit is destroyed in chocolate making or the coca spirit in cocaine production. Our ancestors used these substances in ceremony's for centuries with very simple chemist being done if any at all. I am curious about these natural paths of healing, that encompasses the plant teachers spirit
 
The fact of the matter is Sassafrass just isn't very psychoactive. I tried for years to unlock the secrets of it. I did all sorts of extracts: cold water, hot water, ethanol, acetone, a/b, distillation, kombucha. I inhibted enzymes when taking it. I tried tried all sort of mixtures with other herbs.

At the end of the day, it's nothing moar than a fairly nice rootbeer flavored tea, that may or may not have some medicinal or detrimental effects, depending on dosage.

This is no "organic ecstasy" as some would claim, and while it does have uses in herbal healing, it's unlikely one will be finding a lot of shamanic journey potential here. It doesn't really have any moar therapeutic potential than any other cup of herbal tea.

Consider the case of Ergot and LSD. It's not really in anyone's best interest to be communing with the full spectrum fungal spirit of Claviceps. It's rather dangerous, toxic stuff. However, when a skilled chemist takes it into the lab, they are able to make something incredibly special and valuable from it.
 
Crude extracted sassafras alkaloids provide a couple of hours of mildly empathogenic, mild stimulation followed by a couple more hours of dreamy sedation. If you're lucky.

The powdered bark of Laurus nobilis (bay) is at least as interesting, effects may vary with location, time of year and your relationship with the plant. I urinated fairly frequently at the foot of 'my' tree for five years before gathering the bark from branch trimmings. The tree itself I would estimate at being twenty years old.

Both bay and sassafras are in the Lauraceae, if you're wondering about the seeming non sequitur. Bay contains some benzylisoquinolines similar to those found in sassafras.
 
Thank your your reply & information on bay downfronzero. May I ask you what was your tek for extracting "crude sassafras alkaloids"? Did you do an a/b? I've read cwe, evaporate, put in to alcohol for a month. I ve also read a mek wash then Cwe. Over all there really isn't much information on it
 
Missed this question back then. I'm uncertain of the method of extraction as I did not carry out the procedure myself. It would be logical to believe the alkaloids can be obtained from the aqueous residue in the steam distillation pot when recovering sassafras essential oil.
 
Thank you for your response, steam distation and acetone are both good ideas. I'd really like to find a good a/b method to obtain pure alkaloids. Tho do we know what these "crude" alkoloids really are? I know cinnamolaurine is the most proposed. It would be easier to isolate the alkaloids I feel if we knew exactly what they are. I know sassafras has a lot to offer, it's spirt seems elusive tho. Hopefully someone with more chemistry knowledge can lend and hand in discovering its mysteries
 
Hi all. There must be something going on with sassafras since that's all anyone talks about on the X/MDMA forums. I'm interested in the chemistry and wondered how hard it was to do different things and got to poking around.... Well, it that part of the discretely functioning home lab world, those folks are doing distillations that go on for like 48 hours. And even with the best equipment, it's not like you can just set it and forget it. Not simple distillations either. Vacuum and I think even fractional. Scared me away. I can't imagine trying to learn fractional d on my own. I.e., without hands-on experience under supervision. Does that make me a weenie (or just someone who will probably outlive braver souls)?
 
mikeAtHome said:
Hi all. There must be something going on with sassafras since that's all anyone talks about on the X/MDMA forums. I'm interested in the chemistry and wondered how hard it was to do different things and got to poking around.... Well, it that part of the discretely functioning home lab world, those folks are doing distillations that go on for like 48 hours. And even with the best equipment, it's not like you can just set it and forget it. Not simple distillations either. Vacuum and I think even fractional. Scared me away. I can't imagine trying to learn fractional d on my own. I.e., without hands-on experience under supervision. Does that make me a weenie (or just someone who will probably outlive braver souls)?
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Check this out here


i have a nice bottle of sassafras here too, smells delicious.

fractional vacuum distillation is certainly tedious, i set up a camera to watch the distillation so i am able to leave the room and monitor it.. distillations not 48hours but 6-8hr with constant attention... Catching the fractions at the right time is vital, to get a good seperation you need a slow and constant source of heating, heating mantles and stirring is important for this. Wait a couple minutes too long and get a poor separation, then have to do it all over again.

Not something you pick up over night certainly, but distillation becomes routine to chemist, and vacuum and fractional work themselves in over time...
 
sass root is a pain to get in large quantities, you will most
Iikely kill the tree trying to get enough root bark and that you will spend most of the day trying to dig around to scape off root bark. my suggestion ....order a piper atrium plant , it's used in Mexican cooking under hojas santos and when water steam distilled results in around 90 percent safrol oil which can then be concentrated through distillation further . The plant is a weed and produces leaf matter faster than you can harvest , and it taste great with eggs:grin: trust me it's easier and also better than killing host trees and looking like a weirdo in the woods , you could easily get quantities you are looking for in a few seasons of good home and gardening.

Ha I realize now the op was not interested in safrol oil, disregard the besotted beginning tone . I think however I found a few cinnamon tree species that may work better , and maybe a synth . I need to double check the literature I have and will get back tomorrow with hopefully a better starting point for you . I think cinnamon species would be better starting points for what you're after perhaps.
 
I was able to find a few journal entries on cinnamolaurine the only one I had time to look over was alkaloids of the genus cinnamomum isolation , structure and synthesis of cinnamolaurine in tetrahedron letters no 58 pg 5055. They extracted from an unknown cinnamomum species from New Guinea , I'm out of curiosity looking for the species . It can however be synthesized from 3,4-methylenedioxyphenylethylamine then condensing . But I think this is a bit much , I did find the journal entry on sassafras and cinnamolaurine with in safrol oil but I had not enough time to review it, so I'll post that later , with the cinnamomum species , so far of any interest c . Caphora yields laurolitsine and retiouline if it's of interest to you .
 
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