sublingual ..DMT blotter?

[1Starway7]

This is my attempt at creating blotter DMT /with combined full spectrum rue extract [booth desolved and extracted in 96 percent grain alcohol...

for a food safe blotter paper.... im using very porus and thin coffie filters that are foulded multablel times/....enough times ....to hold drops of tincture securly...
After the alcohol in the blotter is compleatly evaporated...[all alcohol gone] .... it should leave rue and DMT imbedded in the multi layers of the Blotter..
the layers of filter paper should release the actives under the toung and keep most of the actives in one spot preventing most of it from runing down the throat......im positive the rue actives will get into the blood stream very quickly... since the rue and the dmt molecule were compleatly desolved together it is an experament to see if the DMT freebase molecule will also penetrate sublingualy?

The VERY porus coffie filter layers... in the blotter... should release the actives easily into the sublingual area under the toung...
with the rue actives entering first ... possibly surounding the molecule.....it might be like a football game where the rue molecules might act as guards protecting the molecule from atacking enzimes? all theory....worth a try though...
then there is the posibility of adding HPBCD as a molecule transport .. to the mix later and see if it makes the blotter work better/

ive already made one blotter... 5 drops of DMT tincture and 10 drops of Rue seed tincture...not shure the propper ratio yet but more rue can make les dmt active...the blotter in below photos i foulded atleast 10 times ..because coffie filter paper is so thin...the more foulds the more the blotter will hold...

sublingualy...it takes less of everything to work ...unlike the oral method.... that takes much larger doses of DMT and rue..

after fully drying the alcohol out of the blotter your saliva will re wet the blotter and release the trapped alcoloids into the sublingual tissue under the toung..

If...the blotters dont deliver the dmt sublingualy....... the alcohol extracted ....[ rue blotters] may still be very handy! ..... a pre made rue blotter once dryed can be stored for long periods.... this could be a convenient ! and un messy way.... to SUBLINGUALY pre treat your trip!..you can mellow out the fast mercyless DMT only trip by sublingually using the rur blotter before you vape DMT... ....[just hold the paper rue blotter under toung a few minutes or longer before vapeing!].... ...

a little Rue before vaping... is like spreading butter over a hard peice of toast..it slows and mellows the trip [for many] reduces any anxiety and makes the trip more easy to navagate...leaving you with more recall of the experiance....

.[[[after multable dippings in the alcohol extracted rue liquid.]]]... [YOU CAN MAKE THE RUE BLOTTERS AS STONG OR WEAK AS YOU LIKE/...just make shure the blotters are compleatly dry..they will store a long time....store pre made blotters in air tite plastic bag in closet or frige..

I only extracted actives from ...OUTSIDE ...of rue seed shell....[did not crush rue seed!].... just soaking in grain alcohol for a couple days..

ALSO..with rue blotters...there is no need to chew seeds or sloppy droppering the rue liquid under toung to quickly have it swallowed....or having to drink nasty tasting rue tea!

with multi layered blotters the coffie filter paper..... soakes up...and releases what ever is imbedded in it easily ... [the more foulded layers] ....[the more it will hold]...

using grain alcohol...one could desolve hash or hash oil...imbed it in the blotter for sublingual use.... [just filter the leaf particles] first

more research needs to be done on sublingual application....I think..

this blotter idea.. hasent been proven to work yet ....[with DMT molecule]... .. [except im positive the rue itself will get through without any problems]... just a test...it may need The HPBCD transport molecule added? for the DMT to get through...or maybe change the dmt from freebase to different form?

so far ....it appears the alcohol dryed pretty fast..only an hour...leaving all the actives imbedded in the filter layers... Hasnt been fully tryed yet ..but can feel the freebase bite under the toung...may need to dry the blotter over night...

in 2 photos below you can see tube flask soaking the actives ... in grain alcohol]..from the rue seed...under black light...then after a few days,,rue actives transfered by dropper on to blotters...[actives taken only from out side of uncrushed seed shell]

 

[Ruffles]

You gotta seal it on the side that will not touch the tongue with something that is not permeable, it will leak otherwise. That local high concentration will increase absorption.

There is plenty of acids in the mouth to turn them into salts.

So did you bioassay and how much exactly?

 

[1Starway7]

You gotta seal it on the side that will not touch the tongue with something that is not permeable, it will leak otherwise. That local high concentration will increase absorption.

There is plenty of acids in the mouth to turn them into salts.

So did you bioassay and how much exactly?

Well you could seal the blotter off much better ..by first foulding the filter paper atleast 5 times ...[.in one direction ] ... then...foulding it 5 more times across the open ends that way the open sides are not open anymore..
That way.. it will slow down any large leak of actives down the throat...[ a little will get down the throat].... but if its slowed down enough to alow sublingual absorbtion thats all thats needed...

Filter paper is very porus and should work well. .... one should not press on blotter with toung.... just leave the blotter soak up saliva and sit in sublingual area under the toung.. The syrian Rue extract will easily and quickly pass through the sublingual tissue with no problem...
Its the DMT im concerned about... no i didnt bioassay anything yet...


can the tongue absorb sublingualy??
Yes, the tongue ...[and cheek]...can absorb drugs administered sublingually, but it is primarily the mucous membranes beneath the tongue that facilitate this absorption. When a drug is placed under the tongue, it dissolves in saliva and is then absorbed directly into the bloodstream through the thin mucosa. This route allows for rapid onset of action because it bypasses the gastrointestinal tract and first-pass metabolism by the liver. Sublingual administration is commonly used for certain medications, such as nitroglycerin for angina or certain formulations of opioids.

 

[Tripolation]

I find this super interesting and would consider trying it myself. It sounds like if you could nail down the process, you could have very predictable and measurable dosages. Take one for a light experience, take three to meet alien gods in hyperspace. I like the idea of that because changa and aya can be a little on the unpredictable side as far as dosage. I am not sure if that is the case with DMT blotter so correct me if I am wrong. Would DMT blotter be similar to LSD blotter as far as predictability of dosage?

Look at the journal below on bluelight.org that is similar to your experiments. Worth checking out, maybe get some ideas, work out the kinks and whatnot.

Thanks for sharing all this!

Tryptamines - Journal: 50 Sublingual HPBCD DMT Ayahuasca journeys over a years time

Compilation of panaeolus cyanescens or pan cyan experiences & combo with THH or tetrahydroharmine, like organic psilocin LSD, extremely visual, music enhancing & super euphoric...

www.bluelight.org

 

[1Starway7]

I find this super interesting and would consider trying it myself. It sounds like if you could nail down the process, you could have very predictable and measurable dosages. Take one for a light experience, take three to meet alien gods in hyperspace. I like the idea of that because changa and aya can be a little on the unpredictable side as far as dosage. I am not sure if that is the case with DMT blotter so correct me if I am wrong. Would DMT blotter be similar to LSD blotter as far as predictability of dosage?

Look at the journal below on bluelight.org that is similar to your experiments. Worth checking out, maybe get some ideas, work out the kinks and whatnot.

Thanks for sharing all this!

Tryptamines - Journal: 50 Sublingual HPBCD DMT Ayahuasca journeys over a years time

Compilation of panaeolus cyanescens or pan cyan experiences & combo with THH or tetrahydroharmine, like organic psilocin LSD, extremely visual, music enhancing & super euphoric...

www.bluelight.org

Yes using a sublingual blotter would be a nice easy way to trip...i think LSD blotter uses microgram dosages...and DMT uses MG doses...
Im 100 percent postive using the blotter with syrian rue actives will work very fast and well...if taken 10 minutes before vaping DMT...

Im not shure yet the DMT will penetrate sublingually just using a blotter.. idea needs testing...



If some one trys the blotter method please share results...

The address below you left is interesting and incouraging...I think this person used to be on NEXUS a while back. he made some awesome claims!!... of sucess with cyclodextrin.[HPBCD] as a sublingual transport molecule...only he said he used a spoon with DMT and HPBCD powder in heated water to be complexed together and placed under the toung..loosly ..not in a blotter like my idea says...

The idea of using the HPBCD..[.cyclodextrin] ...complexing cyclodextrin... is the method to use it as a sublingual drug carrier... some people have claimed the HPBCD helped them have sucessfull dmt trips [sublingualy]

Some on nexus tryed using ....corn starch...[with DMT].... as a ....cyclodextrin .....substitute//// with varied results

i like this read......[if true]......The HPBCD not only makes the DMT water soluble but greatly increases the penetration due to polysaccharide penetration enhancement "opening up of tight junctions" in the sublingual mucosa as studies show, allowing the DMT to cross from the sublingual mucosa into the bloodstream and cross the blood brain barrier as the potent freebase.

 

[blig-blug]

I think this person used to be on NEXUS a while back. he made some awesome claims!!... of sucess with cyclodextrin.[HPBCD] as a sublingual transport molecule

There was a troll account that used to make claims like that about HPBCD: HPBCD troll accounts. Just in case that's the account you mean.

 

[1Starway7]

There was a troll account that used to make claims like that about HPBCD: HPBCD troll accounts. Just in case that's the account you mean.

yes it could be......If you back track on nexus ......[ there were members that tryed this cyclodextrin method back then....and claimed that the method worked for them!....
a science report also claims it works...as written below...

.....The HPBCD not only makes the DMT water soluble but greatly increases the penetration due to polysaccharide penetration enhancement "opening up of tight junctions" in the sublingual mucosa as studies show, allowing the DMT to cross from the sublingual mucosa into the bloodstream and cross the blood brain barrier as the potent freebase.

but maybe it wont work for all types of drugs?

 

[Ernestine]

There was a troll account that used to make claims like that about HPBCD: HPBCD troll accounts. Just in case that's the account you mean.

It's funny that, isn't it?

 

[Varallo]

This is a really interesting topic. I’ve been using sublingual harmalas and DMT for quite a while, and in my experience, especially when first taking the harmalas, I usually take a proper dose, around 40 milligrams or more, and then add about 50 milligrams of DMT fumarate on top. With that combination, I can have a profound experience.

Although it might not be as strong as vaporized DMT or drinking ayahuasca, it’s still very clear to me that the DMT enters my bloodstream, because the difference in effects is significant. I see fractal spaces and complete storylines that are very similar to what I’d experience with oral ayahuasca. The main difference is that the time frame is much shorter, maybe about an hour for the peak effects, and around two hours total, including the come-up and the gradual return to baseline. The DMT seems to leave the bloodstream much faster than the harmalas.

I’ve been thinking about posting about this, because sublingual DMT fumarate is honestly one of the things I really enjoy doing on a lazy Sunday evening, just before the new week begins. I should mention that, due to long and extensive periods of use, I believe my tolerance has gone down. It’s much easier for me now to access the visuals or the experience, it feels like I can more easily find that space within myself for some reason.

So although it works for me, it doesn’t seem to work for many others, from what I’ve read. You kind of have to search for the experience, let it manifest and unfold, but when it does, it can be very profound. It’s really something worth trying, especially if you have a naturally low tolerance or have built one over time through regular use.

 

[1Starway7]

This is a really interesting topic. I’ve been using sublingual harmalas and DMT for quite a while, and in my experience, especially when first taking the harmalas, I usually take a proper dose, around 40 milligrams or more, and then add about 50 milligrams of DMT fumarate on top. With that combination, I can have a profound experience.

Although it might not be as strong as vaporized DMT or drinking ayahuasca, it’s still very clear to me that the DMT enters my bloodstream, because the difference in effects is significant. I see fractal spaces and complete storylines that are very similar to what I’d experience with oral ayahuasca. The main difference is that the time frame is much shorter, maybe about an hour for the peak effects, and around two hours total, including the come-up and the gradual return to baseline. The DMT seems to leave the bloodstream much faster than the harmalas.

I’ve been thinking about posting about this, because sublingual DMT fumarate is honestly one of the things I really enjoy doing on a lazy Sunday evening, just before the new week begins. I should mention that, due to long and extensive periods of use, I believe my tolerance has gone down. It’s much easier for me now to access the visuals or the experience, it feels like I can more easily find that space within myself for some reason.

So although it works for me, it doesn’t seem to work for many others, from what I’ve read. You kind of have to search for the experience, let it manifest and unfold, but when it does, it can be very profound. It’s really something worth trying, especially if you have a naturally low tolerance or have built one over time through regular use.

This is interesting ...
if you are using 50 mgs dmt and 40mgs harmalla sublingualy... it sounds like less than 50mgs dmt is getting through the sublingual barrier,
But!..atleast.. some DMT is getting through!
50mgs DMT vaporized would be an intense heavy experiance!
And 50mgs sublimgualy should also be a heavy experiance,,,if not heavier,,,so it sounds like ...not all of the dmt.... is getting through ,,,[but some is]..and the harmala is boosting the effects of the lower dose of dmt..
This might not be so bad.... because not everyone wants a stressful shot out of a cannon experiance...
Big question is.....Are you using HPBCD in your dose?? [cyclodextrin]??... there has been some claims from some people that it worked well for them in transporting the dmt molecule through the sublingual tissue...
Rue worked great...But Sublingual DMT hasent worked for me yet...but i may have done something wrong when i tryed it some time ago..
This new idea of using a blotter may give better results because it can hold the dose in one spot longer under the toung....than just using a dropper or spoon...

 

[Varallo]

This is interesting ...
if you are using 50 mgs dmt and 40mgs harmalla sublingualy... it sounds like less than 50mgs dmt is getting through the sublingual barrier,
But!..atleast.. some DMT is getting through!
50mgs DMT vaporized would be an intense heavy experiance!
And 50mgs sublimgualy should also be a heavy experiance,,,if not heavier,,,so it sounds like ...not all of the dmt.... is getting through ,,,[but some is]..and the harmala is boosting the effects of the lower dose of dmt..
This might not be so bad.... because not everyone wants a stressful shot out of a cannon experiance...
Big question is.....Are you using HPBCD in your dose?? [cyclodextrin]??... there has been some claims from some people that it worked well for them in transporting the dmt molecule through the sublingual tissue...
Rue worked great...But Sublingual DMT hasent worked for me yet...but i may have done something wrong when i tryed it some time ago..
This new idea of using a blotter may give better results because it can hold the dose in one spot longer under the toung....than just using a dropper...

You’re absolutely right, I don’t think the entire amount of DMT gets absorbed. It’s more that I use a small spoon with roughly 50 mg on it, and needing a certain amount in your mouth to reach the right strength, rather than expecting all of it to be absorbed.

Just to clarify, I don’t use cyclodextrin or any other enhancers. But I do brush my gums, teeth, and the underside of my tongue with a toothbrush beforehand, and that really seems to make a difference, though I’ve never done a blind test or anything like that. Still, when you’ve brushed your gums and mouth, you can feel the difference.

At some point, I might try a “blotter” experience, hadn’t actually thought of that before. I did experiment once with putting the DMT under a piece of gelatin foil. I’d place it under my tongue, and then stick the foil over it. It turned into this gloopy sort of thing, but I didn’t really feel like it improved absorption much. Personally, I prefer to swish it around in my mouth, and that seems to do the trick, at least for me.

 

[Ernestine]

I have occasionally experimented with a mixture of buccal harmala seeds and dmt to provide a base camp from which to set off on vaporhuasca expeditions.

 

[Ruffles]

There was a troll account that used to make claims like that about HPBCD: HPBCD troll accounts. Just in case that's the account you mean.

Indeed... And without paying much attention I fell into this again. Sorry Nexus.

The subject is great but this weird ass hyping is not. Probably the best place to discuss this is through the new paper that came out assessing sublingual and oral pharmacodynamics of the combo in humans that has been posted in the nexus a few days ago. Can we migrate there for the proper discussion to take place?

This

 

[1Starway7]

Indeed... And without paying much attention I fell into this again. Sorry Nexus.

The subject is great but this weird ass hyping is not. Probably the best place to discuss this is through the new paper that came out assessing sublingual and oral pharmacodynamics of the combo in humans that has been posted in the nexus a few days ago. Can we migrate there for the proper discussion to take place?

This

Im sorry you seem to feel ...your falling into something?... why are you apoligising to nexus?? being open minded is not a crime...

There are others who are quite interested in this idea...The idea of transdermal and sublingual dmt are mountains that have yet to be scaled...

Actualy the subject of sublingual DMT is very interesting and deserves as much attention as it can get...

Being closed minded on a subject ... [just because it isnt understood]... ..[.goes no where]..... its just a dead end road..

a closed minded scientist ...never get much done...but an open minded scientist .... eventually makes discoverys!

We already know about.... smoking and vapeing ...its good effects and bad effects.......sublingual ...and... transdermal... deserves a permanant spot in the list of threads...So atleast we can give it enough time to try to understand it better...

hope this makes sense...

 

[Jamie01]

I have also used sublingual dosing of DMT a lot with harmalas. It does work and I actually prefer it to oral use.

Pretty sure amor_fati had a tek called linguahuasca or something like that.

 

[blig-blug]

Pretty sure amor_fati had a tek called linguahuasca or something like that.

This seems to be the thread: amor_fati's Guide to Juremala WIP

 

[1Starway7]

Just found a blotter method online.. of dipping a cotton cue tip into a liquid solution ..


this gives me an idea...

If DMT/harmalla is in an alcohol solution ..one could leave the cotton cue tip in solution in small shot glass ... untill all the alcohol is evaporated

....compleatly leaving most of the actives embedded in the cotton on tip of cue tip...

dont use untill the cotton tip is free of alcohol;.........;[even though!.... alcohol might increase absorbtion more?. [just a thought]

This way the actives are.... concintrated in small area of cue tip ......that way leaves more control of keeping it in ....best spot under toung.... with the

unused end of cue tip sticking out of mouth a little like a tooth pick ...alowing you to adjust position under toung if nessasery or even alowing you to

acuratly ...press into the sublingual spot a little to increase absorbtion...

maybe ...[finding a cue tip with larger concintration of cotton]..... on end of tip may work better as the cotton will hold more...

Videos

another idea! if your dmt /harmalla was desolved in say ...coconut oil .... after dipping que tip in the oil...one could hold cue tip under toung for while then re dip the cue tip and put back under toung if needed... sooner or later your stoned this way!! no smoking or vapeing needed...



1:48
How To Make Q-Tip At Home (D.I.Y.)
YouTube · omnistyles

 

[Varallo]

Im sorry you seem to feel ...your falling into something?... why are you apoligising to nexus?? being open minded is not a crime...

There are others who are quite interested in this idea...The idea of transdermal and sublingual dmt are mountains that have yet to be scaled...

Actualy the subject of sublingual DMT is very interesting and deserves as much attention as it can get...

Being closed minded on a subject ... [just because it isnt understood]... ..[.goes no where]..... its just a dead end road..

a closed minded scientist ...never get much done...but an open minded scientist .... eventually makes discoverys!

We already know about.... smoking and vapeing ...its good effects and bad effects.......sublingual ...and... transdermal... deserves a permanant spot in the list of threads...So atleast we can give it enough time to try to understand it better...

hope this makes sense...

He Starway,

I think @Ruffles is reacting to the link of @blig-blug that is a warning on the numerous claims of one individual who has serious mental health issues and keeps on repeating the same lies about HPBCD. So within his reply he is referring to the warning, it has nothing to do with not being open minded. I am not sure if @Ruffles is an researcher but scientists don’t reject ideas because they’re close-minded, they reject them because those ideas lack evidence or theoretical framework.

I have also used sublingual dosing of DMT a lot with harmalas. It does work and I actually prefer it to oral use.

Pretty sure amor_fati had a tek called linguahuasca or something like that.

Great to see I’m not alone, do you also use dmt fumarate and harmala Hcl ? And what is your current dosage?

Just found a blotter method online.. of dipping a cotton cue tip into a liquid solution ..


this gives me an idea...

If DMT/harmalla is in an alcohol solution ..one could leave the cotton cue tip in solution in small shot glass ... untill all the alcohol is evaporated

....compleatly leaving most of the actives embedded in the cotton on tip of cue tip...

dont use untill the cotton tip is free of alcohol;.........;[even though!.... alcohol might increase absorbtion more?. [just a thought]

This way the actives are.... concintrated in small area of cue tip ......that way leaves more control of keeping it in ....best spot under toung.... with the

unused end of cue tip sticking out of mouth a little like a tooth pick ...alowing you to adjust position under toung if nessasery or even alowing you to

acuratly ...press into the sublingual spot a little to increase absorbtion...

maybe ...[finding a cue tip with larger concintration of cotton]..... on end of tip may work better as the cotton will hold more...

Videos

another idea! if your dmt /harmalla was desolved in say ...coconut oil .... after dipping que tip in the oil...one could hold cue tip under toung for while then re dip the cue tip and put back under toung if needed... sooner or later your stoned this way!! no smoking or vapeing needed...


View attachment 103275
1:48
How To Make Q-Tip At Home (D.I.Y.)
YouTube · omnistyles

So maybe it’s wise to start with the question of strength vs surface area and then go from there? In my thoughts the choice between applying dmt sublingually in a concentrated spot versus swishing it around the mouth involves a trade-off between maximizing local concentration and increasing mucosal surface area exposure.

For drugs to be a candidate for sublingual admission you need low molecular weight and something that dissolves in well in saliva, dmt as freebase is not that good in dissolving in saliva. To solve this issue a salted version can be used, however this in itself can hinder absorption. For choosing an suitable salted form you can look at the pH of the solution after salting the dmt, the closer you get to the pH of saliva the better, so fumarate is an good option, and Hcl much less so, personally I’d like to try lactic acid to see if that works even better.

The poor performance of DMT salts is also the reason why I think more surface area is preferred to small area with high strength.

 

[1Starway7]

He Starway,

I think @Ruffles is reacting to the link of @blig-blug that is a warning on the numerous claims of one individual who has serious mental health issues and keeps on repeating the same lies about HPBCD. So within his reply he is referring to the warning, it has nothing to do with not being open minded. I am not sure if @Ruffles is an researcher but scientists don’t reject ideas because they’re close-minded, they reject them because those ideas lack evidence or theoretical framework.

Great to see I’m not alone, do you also use dmt fumarate and harmala Hcl ? And what is your current dosage?

So maybe it’s wise to start with the question of strength vs surface area and then go from there? In my thoughts the choice between applying dmt sublingually in a concentrated spot versus swishing it around the mouth involves a trade-off between maximizing local concentration and increasing mucosal surface area exposure.

For drugs to be a candidate for sublingual admission you need low molecular weight and something that dissolves in well in saliva, dmt as freebase is not that good in dissolving in saliva. To solve this issue a salted version can be used, however this in itself can hinder absorption. For choosing an suitable salted form you can look at the pH of the solution after salting the dmt, the closer you get to the pH of saliva the better, so fumarate is an good option, and Hcl much less so, personally I’d like to try lactic acid to see if that works even better.

The poor performance of DMT salts is also the reason why I think more surface area is preferred to small area with high strength.

one could also use two or three normal tips to apply under tounge taped together...and if needed re dip and apply again...
One good thing about ...q tips or blotters ... is it keeps the dose localized atleast for a while in the cotton ... in sublingual area you choose..
When using a dropper it can instantly start running down your throat if you arent very care full..

 

[Varallo]

one could also use two or three normal tips to apply under tounge taped together...and if needed re dip and apply again...
One good thing about ...q tips or blotters ... is it keeps the dose localized atleast for a while in the cotton ... in sublingual area you choose..
When using a dropper it can instantly start running down your throat if you arent very care full..

I agree with the swallowing, but the fact that we are now using an ionic salt of DMT influences the way the DMT is absorbed, so by localizing you will not get the amount of area that is needed to really get the DMT into the system. From the paper, localized drug solutions work well when they are lipophilic but when they’re ionic and highly soluble it’s opportune to increase the surface area, hence why I would like to try the lactic. Anyway I added the article that led me to this thinking.