Surviving the pH

[Gir]

Is there a certain method / formula to calculate if a molecule will be able to survive in highly basic/acidic solutions? Or is there something noticeable about the molecule itself that gives the answer?

-gir

 

[benzyme]

Or is there something noticeable about the molecule itself that gives the answer?

functional groups that are easily hydrolyzable, like ones containing a carbonyl ( C=0 ), are particularly susceptible
to molecular degradation