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The highest DMT dose pharmahuasca

ChrisMMcD

ChrisMMcD

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I'm wondering how much of an oral DMT dose would be needed to achieve an instant breakthrough.
I tried 50mg and felt like I could handle more. My sweet spot seems to be around 60-80mg, but I'm still considering taking a higher dose. I haven't come across any forum posts about extremely high doses of pharmahuasca.

What do you think about taking a dose of 250-300mg of DMT? Would I be able to handle it, and what kind of experience could I expect? Could I potentially reach the same realm as when I vape DMT?
And more generally, what is the maximum safe and feasible oral DMT dose? I have an experience with 10g dry cubensis trips, with salvia divinorum too, so I'm not new to intense trips.

I'm curious to hear your thoughts.
 
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I don't know if there is anyway for it to be "instant" considering that it has to be metabolized and enter the blood stream, which invariably takes time. You may be able to increase the harmala dose in order to get quicker onset. I don't think the amount of DMT will really increase the onset. Eating 3.5g of mushrooms seems to take about the same time to kick in initially as 7+ grams ime. It's just that the total ramping feels faster since one is going deeper with a bigger dose.

250-300mg sounds a bit risky, even with experiences with high dose mushrooms. They're just not the same. I'd recommend finding an interval you feel comfortable increasing by and take several journeys increasing by that increment each time to see how it suits you.

I have not seen anything on a safe maximum dosage for DMT aside from the LD50.

One love
 
Voidmatrix said:
I have not seen anything on a safe maximum dosage for DMT aside from the LD50.
Click to expand...
Bit off topic, but this got me thinking. I don't know why, but I'd always just felt that dmt was something you couldn't physically overdose with, or actually harm yourself. Obviously, I'm not talking about damage to your psyche.
Found this paper Psychedelic 5-Methoxy-N,N-dimethyltryptamine: Metabolism, Pharmacokinetics, Drug Interactions, and Pharmacological Actions and it says the LD50 in mice ranges from 48 to 278 mg/kg, depending on administration method.
Made me sad to think of the poor little creatures being purposefully killed with the spice, just to satisfy our curiosity.

As void says, oral administration would seem to preclude the possibility of 'instant' breakthrough.
 
ChrisMMcD said:
I'm wondering how much of an oral DMT dose would be needed to achieve an instant breakthrough.
I tried 50mg and felt like I could handle more. My sweet spot seems to be around 60-80mg, but I'm still considering taking a higher dose. I haven't come across any forum posts about extremely high doses of pharmahuasca.

What do you think about taking a dose of 250-300mg of DMT? Would I be able to handle it, and what kind of experience could I expect? Could I potentially reach the same realm as when I vape DMT?
And more generally, what is the maximum safe and feasible oral DMT dose? I have an experience with 10g dry cubensis trips, with salvia divinorum too, so I'm not new to intense trips.

I'm curious to hear your thoughts.
Click to expand...
I have taken 150 mg harmala with 300 mg twice. In this case, first the harmala and 30 minutes later the DMT fumarate.

The last time was with a friend who did a cleanse and vomited a little. At the end, he thanked me profusely for the experience. I lay down for a while and found myself in the middle of a nest of snakes of fire, energy, electricity. The OEVs were clear. The natural patterns ran like rivers.

This was in my first tests. Without much information and determined to provoke a 'miração', a vision, with just one dose (in this case two, harmala + DMT). Today I see that it would be more beneficial to ingest several smaller doses over time, as is done ritually. Until the desired level is reached.
 
Voidmatrix said:
I don't know if there is anyway for it to be "instant" considering that it has to be metabolized and enter the blood stream, which invariably takes time. You may be able to increase the harmala dose in order to get quicker onset. I don't think the amount of DMT will really increase the onset. Eating 3.5g of mushrooms seems to take about the same time to kick in initially as 7+ grams ime. It's just that the total ramping feels faster since one is going deeper with a bigger dose.

250-300mg sounds a bit risky, even with experiences with high dose mushrooms. They're just not the same. I'd recommend finding an interval you feel comfortable increasing by and take several journeys increasing by that increment each time to see how it suits you.

I have not seen anything on a safe maximum dosage for DMT aside from the LD50.

One love
Click to expand...
Very insightful way to frame the ramping of high-dose psychedelics. I’ve taken heavy doses of LSD before, looking at my friends and thinking - “This is coming on fast”. It completely makes sense that a high dose would just have more distance to cover in the same amount of time.

In other words, both low and high doses arrive to their respective thresholds in the same amount of time, but at entirely different speeds due to covering different distances.

Great point. Will have to share that with my psychedelic buddy when he gets into town.
 
I had once a pharmahuasca of 200mg harmalaHCL, then an unknown time in between as it is too long ago, then followed by 450 mg freebase D that was due cleaning out a little container. All of the energy turned out as a suffering and I wished to be dead to make it stop.
The biggest mistake was that I was tired when embarking. I was not able to conduct the flow, like a little copper wire that got too much electricity trough it. I could only burn, for hours.

It was not only physically demolishing as a feeling but I got an answer to the question why I lived as a being in these realms, the key to my existing and that answer was everything I didn't want to hear because it was the most perverted reason imaginable, so there I got also a psychological whoopass as an extra push in pain valley.

I remember the phase to be able to determine a tree in the garden trough the window. I begged to "this realm" as if it was a raft while I was drowning in pain. Never before I had so much hope and relief to see a glimpse of this earthly layer. Since then I consider the thought that this earthly layer of existence, which we easily condemn due confinements and limitations, could as well be a safe "parking spot" to be in. With many limitations that act as safeguards rather than a jail. Because without limitations all is possible and that ain't necessarily nice.

Later I learned to integrate the lesson, especially the painful psychological one. As I look at it now, it was not fully wrong, it was poorly/one sided interpreted. During that trip I engaged in the worst possible interpretation. Probably that way it could feed itself in a self affirming circle, a self affirming truth, a looping effect. I made it worse than necessary and fueled the shock myself unaware.

Later, talking to buddies about their worst trips, the item of not being well rested or suffering from accumulated sleep deprivation, a disturbed bio rhythm ..., returned as a common ground. It's an ideal hummus for things going potentially south. Your armor is gone, your resilience is a rusty pile of gears.
Sometimes this might open doors positively too I'm sure of that, but it's a bit russian roulette with a bazooka.

Do I consider this a bad trip? Yeah and no, according how to label it. I did learn things otherwise impossible, insights that help me put things in perspective.
Would I do it again? Absolutely no, it was utter torment.
 
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