The way I understand it is that, in the 17th century, the Age of Enlightenment came along. An attempt to build a rational world, there was a clear and certain desire to banish superstition, the power it held over humanity, and remove the perceived stranglehold it had on human growth and development. Reason would strip the snakeoil salesmen and bishops and witches of their authority, and humankind would be free.
The great works of the Enlightenment - Jefferson's Bible, Principia Mathematica, Discourse on the Method, amongst others - stand as a testament to free future generations with the rigour of pure logic.
But upon these noble aspirations the soul of Man was dashed; we lost something intrinsically human in the process. And as Newton's clockwork universe has since proved an inadequate model to explain the weirdness of quantum reality, we have lost the language and thinking that allows us to accept uncertainty, wonder and magic.
I think about the relatively recent discovery of fractal geometry; despite its now obvious primacy in Nature, this underlying structure was completely ignored for hundreds of years, as we ignored the intrinsic geometry of trees, clouds, coastlines and mountains, because it didn't fit the reductionist model that has guided human development sicne the Enlightenment. I believe we are in the same position now, ignoring the reality of human experience in favour of theoretical models that are simply not adequate ... a redeveloped sense of wonder and appreciation of the fundamentals of human experience are needed to redress the balance.
And yes - it's definitely a meth pipe; the kids studying one of ron69's extraction teks in the book, because they didn't have the internet back then ...