• Members of the previous forum can retrieve their temporary password here, (login and check your PM).

THH and Cacao

Migrated topic.
Hahaha very interesting. Check out the study I posted earlier on regarding PEA and MAO-B Inhibitor in humans. SWIM has tried PEA alone and it is orally active around 60-100 mg. The effects are not much but definitely a noticeable mood enhancement and some mild peripheral effects. SWIM is very curious to see how this will play out in combo with MAOIs and THH as well as with theobromine and caffeine.
 
I found an interesting article saying that the effects of methylxanthines result from there activity on serotonin neurons. Check it out:

Brain Res Brain Res Rev. 1992 May-Aug;17(2):139-70.Links
Caffeine and the central nervous system: mechanisms of action, biochemical, metabolic and psychostimulant effects.

Nehlig A, Daval JL, Debry G.
INSERM U 272 Université de Nancy I, France.
Caffeine is the most widely consumed central-nervous-system stimulant. Three main mechanisms of action of caffeine on the central nervous system have been described. Mobilization of intracellular calcium and inhibition of specific phosphodiesterases only occur at high non-physiological concentrations of caffeine. The only likely mechanism of action of the methylxanthine is the antagonism at the level of adenosine receptors. Caffeine increases energy metabolism throughout the brain but decreases at the same time cerebral blood flow, inducing a relative brain hypoperfusion. Caffeine activates noradrenaline neurons and seems to affect the local release of dopamine. Many of the alerting effects of caffeine may be related to the action of the methylxanthine on serotonin neurons. The methylxanthine induces dose-response increases in locomotor activity in animals. Its psychostimulant action on man is, however, often subtle and not very easy to detect. The effects of caffeine on learning, memory, performance and coordination are rather related to the methylxanthine action on arousal, vigilance and fatigue. Caffeine exerts obvious effects on anxiety and sleep which vary according to individual sensitivity to the methylxanthine. However, children in general do not appear more sensitive to methylxanthine effects than adults. The central nervous system does not seem to develop a great tolerance to the effects of caffeine although dependence and withdrawal symptoms are reported.
 
thread resurrection!

today I tried a cacao-rue combo. only been 30-40 minutes since I took it. 4g rue made into a tea, drank the tea and then a minute later ate 6g raw cacao beans over the course of a few minutes. did this after waking up so on an empty stomach so far.

I have been drinking 3-4g rue teas every now and then over the last month. so i'll take notice of the differences that the cacao adds.

all i can say is so far this last 15 minutes has been a very long 15 minutes! but not in an unpleasant way.
feeling a little warmer in the face and only a tiny bit shakier in the stomach than usual. but just like rue it is not debilitating in any way. relaxing is REALLY relaxing, but at any moment I can get up and go, movements have more flow.

i'll be back tonight with the rest :)


edit1: had a turkey-cheese-red-pepper-fermented plum sauce sandwich at t+1:00, then a white cream scone at t+2:00. no nausea or headache at all (I've never gotten nausea from straight rue tea either)

edit: t +3:00-3:30 interesting. a few things to note later but, most prominently... when I tried to take san pedro (there was some confusion as to the dose and weight, and I ended up probably drinking a half-dose) the thing I noticed most then was that... when the sun was in my field of vision, I felt no need to squint as I usually do. it did not hurt even in the slightest to look at it for a second or two.

a similar effect is happening now...not as strongly for sure. definitely can't look at the sun even for a second, but in the peripheral it is totally non-confrontational.

there is... a presence between my skull and my eyebrows, and also at the back-left of the base of my skull. it's not a weight, it's not a pulsing, it's just there...
for the past few hours I have definitely felt... under the effects of something, it is not subtle but it is not overwhelming either.

the feeling of overall general contentment and time either dilating, or not being that concerning, are still on strong. straight rue tea usually only lasts a couple hours for me and this is still quite present.

perhaps this dose was a little strong, as there is enough weight in the limbs to bring a present desire to lie down in the park and drink fruit juices. maybe it's just hot out and it's a slow day at work. I love my job.

there's an african drumming and dance concert in a few hours, it would be nice if this was still in good effect when that is in full swing.

more at the end of the night :)
 
Back
Top Bottom