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5-htp

Migrated topic.
Benzyme can I ask you to elaborate on aniracetam as it relates to dmt. Would it be considered a potentiator ?
 
possibly

according to japanese research, it acts as a 5HT2a modulator (something like a volume knob on
your stereo), and DMT is a 5HT2a ligand (molecule which binds 5HT2a).

case 1: I vaped what should've been a threshold dose, 8 mg, and took 750 mg aniracetam...the result
was akin to a 10 min heavy acid trip, or a couple grams of panaeolus cyanescens. extremely visual

case 2: I ate 3.2 g cubensis, and got mostly a body buzz with some visuals..an hour into it, I took 800 mg aniracetam. Prior to this I was all smiles and joking with a friend, who took the same. 15 mins later, we were both stunned; on shulgin's scale, we had shot up from +.5 to +++
 
I,m wondering if aneracetam would be contraindicated
With maoi or harmala source such as caapi specifically .
Hard to find much data on this.
 
I'm going to check and see if I can get aniracetam at my supplement store. Benzyme, do you have any experience with Piracetam? I read that Piracetam is a cyclic derivative of GABA, I don't fully understand what this means yet, but my alpha brain contains GABA. Would taking Piracetam or Aniracetam along side GABA have any adverse side effects? Or would I need to adjust dosage according to this?

NamRa said:
rOm, I had one experience with Mucuna pruriens extract.

i just realized that my alpha brain supplements contain Mucuna Pruriens. And you said this had effects with DMT? I took alpha brain the day I had my breakthrough dose. I wonder how it affected it. i should probably research a little more about these supplements if I am going to be taking them in conjuction with DMT.

This is what I take (if anyone is interested) and i feel amazing. I'm working on a few hours of sleep, which for some reason every fri sat and sun (days off) I end up waking up after only a few hours of sleep and cannot go back to sleep. Yet i feel amazing.

(per day)
(1) 1000 IU Vitamin D3
(2) 500 mg L-tryptophan
(2) Alpha Brain
Which contains per 2 pills:

Alpha GPC (L-alphaglycerylphosphorylcholine) – 120 mg
Huperzine A – 100 mcg + Huperzia Serrata - 20mg (.5% Huperzine A)
Vinpocetine — 5mg
AC-11 – 350mg
Bacopa (20% Bacosides) — 500 mg
Pterostilbene — 250 mcg
Mucuna Pruriens (50% l-Dopa) — 200mg
GABA — 300mg
Oat Straw (10:1) — 300 mg
Vitamin B6 – 15 mg
 
GABA in supplement form doesn't pass the BBB very well, neither does piracetam for that matter. I've had piracetam, which needs "attack doses", probably to overcome this shortcoming. Piracetam, although loosely structurally-related to GABA, does not necessarily act on GABA receptors. Instead, it acts on the adjacent AMPA-1 receptors as an agonist, and is thus has an excitatory effect. Aniracetam has even higher affinity for AMPA-1 (though a shorter half-life), and is lipophilic, so it readily passes the BBB
 
I wonder if taking aniracetam and alpha brain in conjuction with DMT if it would be too much.

Thanks benzyme. I'm prolly gonna follow you around a little, the information your spewing is addictive.
 
Hyperdimensional Cuttlefish said:
I take 5-htp and tryptophan both to decrease "aggression" and increase general "calmness" over the course of the day.

There is a bit of research out there re: testosterone, serotonin and aggression. For me it's been an emotional lifesaver.

Will have to check out aniracetam though.

Do you mind me asking how long youve been taking it? Ive known about it for a while, some people use it as an anti-depressant. But ive heard heard using daily moderate doses could have a negative impact after a while. Would like to hear more from people that use it often. I just dont really trust doctors because they are to quick to push whatever the new BIGPHARM SSRI or whatever the fuck it is now.
 
I was taking 5-htp for awhile but switched to L-tryptophan recently. All in all I've been taking these for several months maybe more. I do, every once in awhile, take a few days off from everything. I have not found any adverse effects ever. They are amazing to help you regulate your attitude.
 
anrchy said:
FluffyClouds said:
Great talk guys,

Which would be overall smoother?: (for psychoactive potentiation effects)
tryptophan or 5-HTP

Neither of these potentiate psychedelics.
Ok, Thank You for the reply.

May I please ask regarding tryptophan vs 5-HTP vs Melaition , whats your ex experience?.

Thank you.
 
FluffyClouds said:
anrchy said:
FluffyClouds said:
Great talk guys,

Which would be overall smoother?: (for psychoactive potentiation effects)
tryptophan or 5-HTP

Neither of these potentiate psychedelics.
Ok, Thank You for the reply.

May I please ask regarding tryptophan vs 5-HTP vs Melaition , whats your ex experience?.

Thank you.

Could you be specific? I have been using tryptophan with good results.
 
May I please ask, how is L-Tryptophan better than 5-HTP?, (which benefits,etc).
And does Tryptophan effect something else just than converting to 5-HTP ???

Thank you.
 
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