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7-Hydroxymitragynine (Kratom Alkaloid tablets)

manifest_jynx

Machine Elf
Donator
Hey everyone was just wondering if anybody who does kratom has ever tried these? They sell them at my local smoke shop and they work amazing for pain!
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7-Hydroxymitragynine is a terpenoid indole alkaloid from the plant Mitragyna speciosa, commonly known as kratom. It is a human metabolite metabolized from mitragynine present in the Mitragyna speciosa (Kratom).
7-hydroxymitragynine (7-OH) binds to opioid receptors like mitragynine, but research suggests that 7-OH binds with greater efficacy.

I am an opiate addict in recovery (going on 3 years now) and I try not to take kratom too often unless I'm really hurting physically and lately I've been dealing with costochondritis due to a slipped rib so my pain is pretty bad some days and I just reinjured myself a couple days ago.
Usually just kratom powder isn't enough (unless I take a ridiculous dosage) to really do the trick for any sort of psychoactive feeling or pain relieving effects for me but I stumbled on these a couple weeks ago and they really do the job! However please keep in mind they do feel unsettlingly close to an actual opiate and could definitely be WAY more addictive than just kratom itself.
The first time I tried these I got a box of 5 15mg tablets and spaced my doses out over 4 days, the 5th day was a living hell and it felt like I was going through morphine withdrawal again but it was over after a day and immediately decided I shouldn't get any more for the time being so you definitely gotta watch out and not dose to often with these.

I've been getting through this healing process with nothing but Cats Claw, Capsaicin topicals, and a ton of CBD (topical and edible) and cannabis and felt it was improving until a few days ago, I'm pretty sure I reinjured myself somehow. I try my best to not take any other pain killers or dull the sensation of pain I'm feeling because I feel it's good to listen to what my body is going through and not just ignore it but today I had a chiropractic adjustment to pop my rib back in place and I was really hurting afterwards. Due to how sore I was I decided to pick up a 2 pack of these and I gotta say they work great and I'm feeling pain free and very good right now. Probably not getting anymore after these are gone because I know myself and definitely shouldn't pick up a new habit nor do I want too.

For anybody on the Nexus who takes kratom I highly recommend these if you can find them! So much more effective but definitely more addictive so keep that in mind! Also the withdrawals are nasty and can come on within a couple of doses so if you decide to try this please use with caution!

Much love ❤️
 
I have tried them. I bought 2 packs and got a free sample of one 7 hydroxy and one Pseudoindoxyl with each pack. I have a low opioid tolerance and 1/2 of any of those gives me a significant effect.

On another board, there have been discussions about them and everyone says that tolerance shoots up very fast and withdrawal sucks. People are buying the pure powder sometimes and getting rather severely hooked, apparently.

Thing is they also supposedly completely ruin your Kratom tolerance, which would be logical. I don't take Kratom more than once a week and I can get a nice stimulating effect which will get a lot of work done on a gram or two. I don't want to screw that up and I will strongly attempt to not purchase any more of these.

That said. Yes, it's rather pleasant. It's definitely as strong as Vicodin.
 
got a free sample of one 7 hydroxy and one Pseudoindoxyl
Would you say Pseudoindoxyl is stronger than 7-OH? I've never personally heard of it before but it looks interesting.
And I know what you mean this stuff is very effective if you don't have an opiate tolerance I also don't have a kratom tolerance because I don't take it much anymore, also a good reason I try not to take these unless it's needed 😅 probably won't get anymore for a while after these are gone
 
Would you say Pseudoindoxyl is stronger than 7-OH? I've never personally heard of it before but it looks interesting.
And I know what you mean this stuff is very effective if you don't have an opiate tolerance I also don't have a kratom tolerance because I don't take it much anymore, also a good reason I try not to take these unless it's needed 😅 probably won't get anymore for a while after these are gone
The Pseudoindoxyl seems more sedative. Maybe a somewhat stronger effect with somewhat less euphoria. I've only taken it once :) Took 1/2 once, gave my lady a half, and have one pill left.
Online, people say it really works if you make your dose 1/2 pseudo and 1/2 7oh, but I dunno.
I hadn't taken Kratom in months and took some a week or two ago and was surprised at how much I got done while in a good mood. (I'm nearly 70) That's a helluva tool and I don't want to lose it.
 
BREAKING: The FDA just announced they will be recommending to the DEA 7-OH or 7-Hydroxymitragynine be labeled a Schedule 1 Controlled Substance
Im honestly so glad because the last few months I've been seriously hooked on this stuff and it's a battle to stop. Im so ready for this stuff to be banned to be honest
 
Mitragynine degrades into 7-OH. 7-hydroxymitragynine (7-OH-MIT) is a metabolite of Mitragynine. Mitragynine is the primary alkaloid of kratom leaves while 7-OH-MIT is a minor constituent. MIT & 7-OH modify each other. A friend of mine who can handle himself does a ratio of like 20mg pure mit / 5mg pure 7oh. (It is not a dose I recommend to people, and he doesn't even use it every day or every week.)

When you eat Mitragynine, it partially becomes more 7-OH when processed through the liver etc. Not a huge conversion but its the main metabolite.

The 7-OH is definitely dangerous, because opiate addicts generally lie to themselves the most. Banks starting to reject transactions.

If you're only taking 7-OH, it's potentially gonna be rougher on you in terms of addiction.

When I saw a youtube vid of vendor touting a pure 7-OH supplement as a way 'to get off opioids' I was like.. here we go... Liars, greedy, selfish. It IS an opioid.

It's truly safer than 'real opiates' in terms of fatality though.

Ultimately it's something I don't need because good leaf doesn't bother my belly and I keep my dosing pretty low when I'm on it. When I went as high as a powdered tablespoon at a time daily I did have to learn to taper down and off to make it gentle on myself, but it was not an overly big deal to do so. I stay at 1 teaspoon / 2.1g at a time now when using, and I use it in phases for it's benefit. I'd rather do that than get Rx'd Vicodins, Percocets, Oxycodones, OxyContins, etc from doctors. Wouldn't touch heroin, or Fentanyl.

I don't believe in just demonizing and forbidding and banning things for everyone because some people have the issues, because it is not fair. However, like I said, companies selling as much 7-OH as they can claiming it's miraculous safety really piss me off, as they're obviously in it for the $ profits way more than being helpful for people.

I've kept a mountain of leaf around and even grew some bushes since like 2004, not because I ongoingly use mountains at a time habitually, but because it is a worthy and useful substance. I've grown a lot of opium poppy flowers and keep those around always as well, but less work and/or money goes into having Kratom on hand so that gets reached for more often.

Remember, people and their greed or their addiction issues ruin good things for people, and it is not that it is not yet another good thing, and even natural, medicinal, and having some beneficial qualities to be respected.
 
manifest_jynx & ABe©eDarian thank you for your opinions on this. I have no prior knowledge of this substance, but as someone with a history of chronic pain I can see where any substance like this could become a problem quite easily.
 
manifest_jynx & ABe©eDarian thank you for your opinions on this. I have no prior knowledge of this substance, but as someone with a history of chronic pain I can see where any substance like this could become a problem quite easily.
I only started using this stuff because I injured myself a few months ago and didn't wanna go back to actual opiates. Now I can't stop using it. With my history of opiate addiction I should have never tried this stuff. I recommend finding better alternatives for pain management
 
I don't have a problem with law and order looking out to prevent greediness from preying on people in need, just an issue with any governmental force trying to prevent me from having what I choose. But I do not harshly judge people who get hooked and then feel desperate for more dosing because I've been there myself with my own issues. For me mostly it was a severe tobacco and nicotine addiction, which I finally kicked by avoiding smoke and vapor and tapering off very slowly with patches.

If it might help at all with anyone struggling, go with quality 3rd party tested leaf, and get tablespoon, teaspoon, 1/2 tsp, 1/4 tsp, 1/8th tsp, 1/16th tsp, 1/32nd tsp, 1/64th tsp kitchen measuring spoons. Mark on the calendar a very eased off tapering schedule, and ween yourself off of as you may know you need. I make capsules for family like the family snake oil pharmacists, hehehe. I guess some can't bear to taste the leaf powder, and I just shake/mix the doses with warm water in small tupperwares with lids. Could do that and use a quick chasers to wash down the taste. I guess tapering down could also be done with capsule amounts and different sized capsules.

Remember, addiction may not be your failing as a person, just an inability to get your needs met. More power to you.
 
I don't have a problem with law and order looking out to prevent greediness from preying on people in need, just an issue with any governmental force trying to prevent me from having what I choose. But I do not harshly judge people who get hooked and then feel desperate for more dosing because I've been there myself with my own issues. For me mostly it was a severe tobacco and nicotine addiction, which I finally kicked by avoiding smoke and vapor and tapering off very slowly with patches.

If it might help at all with anyone struggling, go with quality 3rd party tested leaf, and get tablespoon, teaspoon, 1/2 tsp, 1/4 tsp, 1/8th tsp, 1/16th tsp, 1/32nd tsp, 1/64th tsp kitchen measuring spoons. Mark on the calendar a very eased off tapering schedule, and ween yourself off of as you may know you need. I make capsules for family like the family snake oil pharmacists, hehehe. I guess some can't bear to taste the leaf powder, and I just shake/mix the doses with warm water in small tupperwares with lids. Could do that and use a quick chasers to wash down the taste. I guess tapering down could also be done with capsule amounts and different sized capsules.

Remember, addiction may not be your failing as a person, just an inability to get your needs met. More power to you.
An old junkie trick is supposed to be making a fairly large solution of an opiate and dosing every day from that and then filling it back up with water.

Like, make a pint or a quart of your water solution and make it to where a dose is a teaspoon or a shot, whatever. Every day, take your teaspoon and put a teaspoon of water into the bottle, keeping it full.
 
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Sure. Tapering down must make things a lot more comfortable with any opioid. Not only with my lightweight use, but with more significantly addictive dosing.

I think a lot of people get into dosing on whatever they're given, at whatever amount, at whatever purity, of whatever substance. Then when one supply runs dry they may go about getting a fix from whatever comes down the pipeline. Doctors prescribing, then cutting people off leads to a ton of problems as many of us know.

Truth be told I think opiates/opioids are valuable, and the original opium stuff from the poppy flower and the kratom leaves are where it's at for my personal interest. By the time all the problems had are with doctor Rx'd prescription meds and street drugs I'd say we have a problem to reckon with in more logical ways.

I think some find kratom leaf powder hard on their belly, whereas I can stomach it pretty well on healthy days. And the convenience of skipping raw plant matter and taking pills with pure alkaloids gets a few addicted to say the least. If it were 'opiates for the masses' in ways we were all educated on how to go about it successfully if at all I think a lot less of us would have problems with natural stuff and raw material, let alone purified alkaloids, addictive doctor prescribed pain meds, dirty street drugs, and maybe even heroin overdoses and even fentanyl. Sometimes cops know it as they've saved a few lives with Narcan up the nose and never heard of people just having flowers and/or leaves and teas and tinctures and being relatively successful self-medicating. Opes are not to be partied with, because it can dig a deep hole that's hard for people to get out of, and plays part in ruining lives. Kratom though really does have so much less mortality to it in general, even though some google search engine results seems to insinuate seizure, coma, death etc beyond what is realistically happening with a simple relationship with the plant. Then it gets into these white pills with purified alkaloids in them while the sellers claim it to be a godsend, and that really goes against my standards, not only because of getting my personal access to it threatened, but because I care about people not being taken advantage of for money. These are the types of things I'd say to RFK Jr. if I were communicating with him, because some of his motives I might actually agree with, which is to be protecting people.
 
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