I have smoked many types of mushrooms with no effects, So i cant pull from my personal experience. I have not smoked the A. Muscaria but i have read mixed reviwes on smoking it, some say it works others say it has no effect. Personally i use Cannabis as a changa and it has amazing effects. Amanita muscaria is also toxic so i would not use an MAOI with it.
~Amanita muscaria poisoning typically occurs in either young children or people ingesting it for a hallucinogenic experience.[12][46][47] Occasionally, immature button forms have been mistaken for edible puffballs.[48] Additionally, the white spots may be washed away during heavy rain and it can then appear similar to the edible A. caesarea.[49]
Amanita muscaria contains a number of biologically active agents, at least two of which, muscimol and ibotenic acid, are known to be psychoactive. A toxic dose in adults is approximately 6 mg muscimol or 30 to 60 mg ibotenic acid;[50][51] this is typically about the amount found in one cap of Amanita muscaria.[52] However, the amount and ratio of chemical compounds per mushroom varies widely from region to region and season to season, which further confuses the issue. Spring and summer mushrooms have been reported to contain up to 10 times as much ibotenic acid and muscimol compared to autumn fruitings.[46]
A fatal dose has been calculated at approximately 15 caps.[53] Deaths from A. muscaria have been reported in historical journal articles and newspaper reports;[54][55][56] however, with modern medical treatment a fatal outcome would be extremely rare.[57] Many older books mistakenly list it as deadly, giving the impression that it is far more toxic than it really is.[58] The North American Mycological Association has stated there are no reliably documented fatalities in the past 100 years.[59] The vast majority (90% or more) of mushroom poisoning deaths are from having eaten either the greenish to yellowish death cap (A. phalloides) or one of the several white Amanita species known as destroying angels.[60]
The active constituents of this species are water soluble, and boiling and then discarding the cooking water will at least partly detoxify A. muscaria.[61] However, drying may increase potency as the process facilitates the conversion of ibotenic acid to the more potent muscimol.[62] According to some sources, once detoxified, the mushroom becomes edible.[63]~
en.wikipedia.org