Imo, it doesn't matter at all how potent something is (the dosage needed for full effects), i wanna know how powerful in effect something is. Sure you can take a high/heavy dosage of whatever and get a powerful experience or whatever, but how powerful or intense of an experience is it compared to something else? Power and potency are two different things, the potency plays a role in how powerful an experience is but the effects ultimately determine how powerful the experience is. For example, i could drink a lot of Coffee and enter heavy dosage territory, but i wouldn't consider the ensuing Coffee/Caffeine experience to be nearly as powerful compared to the effects that something like oral DMT would cause. So potency only really refers to dosage, how powerful something is depends on the effects it causes and how intense/powerful those effects are.