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Depression Chemical Imbalance Doesn't Exist

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DMT Psychonaut

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Experts Say...


This is something I wasn't aware of. Does anyone here have an informed opinion to add?

I can't wait to dish this out to certain people. It's such a drag when people use chemical impalance as an excuse. :thumb_dow
 
DMT Psychonaut said:
Experts Say...

I can't wait to dish this out to certain people. It's such a drag when people use chemical impalance as an excuse. :thumb_dow

So, you can't wait to hurt some people who are already hurting? That's nice.

Maybe these people are right, but do you sincerely believe that depression cannot be caused by problems in the body, and that when someone is depressed, it's their fault?
 
sounds like a load of crap to me.

It is well understood that the imprints that form early on in a childs development for example set up feeback loops later on in life that correlate to neurotransmitter levles, oxytocin level etc in the body.

This has been directly proven in mice studies as far as I know. Here is a video with Gabor Mate on brain development and addiction that explains this and depression is very closely tied to all of this...


Often people dont like the idea of a "chemical imbalance" because of the approach big pharma has to the whole thing where they just sell people more drugs that do worse things to them and get them hooked. There are however, often other way of dealing with the issue.

Take MDMA abuse for example..people get depressed after heavy MDMA abuse, because there is a downregulation of seratonin that results..how is that not a chemical imbalance related depression?

The same goes for stress..stress changes the levels of chemicals and neurotransmitters in the body..

Look at people who take iboga and are rid of depression afterwords, while flooded with noribogaine..if there was no such thing as a chemical imbalance related depression that why would certain chemicals that shift brain chemistry more than others(like ibogaine) be so useful in relation to all of this?

Saying there is no such thing as a chemical imbalance in relation here is like saying there is no such thing as a nutritional imbalance. I mean come on, use some common sense and think about it. I am sure there are articles on that same site talking about eating healthy diets to feel well and happy etc..which change body chemistry.

It sounds like the person who wrote that has some issues with big pharma, which I would share..but the rest of it just sounds like bs.
 
"I can't wait to dish this out to certain people. It's such a drag when people use chemical impalance as an excuse. "

Maybe you need to do some more inner work if you are really just so keen on going out and telling people they dont really have any problems etc just because of this shotty article you read. Sounds like you have a biased agenda, and should do some more research to better inform yourself.
 
I follow the OPs opinion here. I have been studying how SSRIs work and why they are prescribed and it's a bunch of uneducated guesswork. My gf was prescribed Paxil and all it does is mask your emotions to give you the illusion that your feeling less depressed.

Doctors never do testing I you to see what your serotonin levels are. They just say hey take this. When you come off SSRI's you get a flood of emotions returning to you and you don't know how to deal with it. Depression is usually caused, and probably only caused, by an event in your life. Your body doesn't simply create less serotonin to make you feel depressed. There are many more things going on in your body. Depression is a defense mechanism to help you out of a situation. Keeps you from wanting to continue what is causing it.

Therapy should be the number one prescribed thing to treat it. Not medication. Also interrupting the reuptake of serotonin doesn't completely guarantee that you get all that serotonin into receptors. They have more time to also be destroyed by MAO's.

Maybe yes saying that you can't wait to dish this out to people who use it as an excuse, but could the op possibly be referring to other people rather tab depressed people on meds?
 
jamie said:
DMT Psychonaut said:
"I can't wait to dish this out to certain people. It's such a drag when people use chemical impalance as an excuse. "
Maybe you need to do some more inner work if you are really just so keen on going out and telling people they dont really have any problems etc just because of this shotty article you read.

I wasn't really intending on doing anything, other than suggesting that, maybe certain people could consider alternatives to pharma meds. :oops:

jamie said:
Sounds like you have a biased agenda, and should do some more research to better inform yourself.

Ha! Well I guess I did have an ex-girlfriend in mind, when I said that, good guess 😁

She always seemed to play on that "it's not my fault that the chemicals in my head are screwed up" and I felt she milked it more than necessary.


However that's why I like to come to the Nexus to seek informed opinions from those which I might consider to be a little more experienced with wizdom or maturity, than my current self. Thanks for the advice.
 
Imo fear of death (death of the ego, reputation, physical death, spiritual death etc.) is the root of all depression and imbalances in the personality and brain chemistry. That's was my first thought when i read this. It's just a guess off the top of my head. That's why i think people (never done aya or smoked dmt) who take ayahuasca or smoke dmt face their death within the very first or first couple of sessions (especially with aya) of using it to move on to actually living their lives to the fullest and not having the fear of death lodged so deep in their minds from social programming and conditioning through the means of all kinds of propaganda and technological threats along with false medications & artificial ingredients and genetic modification of all kinds of crap that are prescibed to further suppress your mind and numb your physical senses keeping you asleep in your mind further to what's actually going on in your own mind!

The medical industry profits from artificially created human suffering. If we ate & drank & got our medicines only from the unaltered, non-genetically modified, non-chemically-labratory-synthesized, non-artificial fruits of Mother Earth, we would not see diseases or mutations in babies and other phenomenon - which are caused by mercury being in vaccines that's been proven to cause autism and stuff like that etc. etc. etc. etc. etc. it goes on and on and on.

After all we have co-evolved with plants for possibly millions of years. We as humanity, because of the government horse manure who have purposely separated us from nature and even from each-other, have separated as far as we can go imo without self-destructing life on Earth. It's time for change and it is happening incredibly fast, at least within the human psyche with the help of psychedelic plants and the information from the internet. We will overcome! :thumb_up: :thumb_up: :thumb_up:
 
anrchy said:
I follow the OPs opinion here. I have been studying how SSRIs work and why they are prescribed and it's a bunch of uneducated guesswork. My gf was prescribed Paxil and all it does is mask your emotions to give you the illusion that your feeling less depressed.

Doctors never do testing I you to see what your serotonin levels are. They just say hey take this. When you come off SSRI's you get a flood of emotions returning to you and you don't know how to deal with it. Depression is usually caused, and probably only caused, by an event in your life. Your body doesn't simply create less serotonin to make you feel depressed. There are many more things going on in your body. Depression is a defense mechanism to help you out of a situation. Keeps you from wanting to continue what is causing it.

Therapy should be the number one prescribed thing to treat it. Not medication. Also interrupting the reuptake of serotonin doesn't completely guarantee that you get all that serotonin into receptors. They have more time to also be destroyed by MAO's.

Maybe yes saying that you can't wait to dish this out to people who use it as an excuse, but could the op possibly be referring to other people rather tab depressed people on meds?

Okay, so what does any of this have to do with the idea that a chemical imbalance has no relation to depression? I agree that big pharma creates often more problems than were there in the first place..but that is not really what the name of the this thread implies. This thread is about chemical imbalances in relation to depression and similar states like anxiety etc(they often go together). If you read and listen to the links I posted, there are many cases where this relationship is well understood..Women who were abused as children produce less oxytocin later on in life..infants who are not nurtured and loved by their mothers do not produce oxytocin and so the pathways in the brain associated with love and joy etc are underdeveloped leading to depression and anxiety later in life..these people then seek out exterior forms of these chemicals to compensate(often with opiates)

You cannot dispute this and sound credible.

What you are saying is that you dont like the approach that big pharma takes, which I agree with..but that is a different subject. It does not matter that someone goes to therapy instead, takes ayahuasca, or just tries to gain a better outlook through meditation etc..if the problems arise from early truama that disrupts normal chemical processes and feedback loops it is a chemical imbalance, and they very much have been proven to occur.
 
"Imo fear of death (death of the ego, reputation, physical death, spiritual death etc.) is the root of all depression and imbalances in the personality and brain chemistry."

Please go click the links I posted before you post. Everyones depression and anxiety is NOT just due to fear of death etc..things are not that black and white. The relation between childhood abuse/abandonment etc and anxiety/depression is well understood.

If this discussion continues on this way this thread will be locked. This is a serious topic that is going to be relevant personally to some people here and the responces should be better informed than this.
 
anrchy said:
I have been studying how SSRIs work and why they are prescribed and it's a bunch of uneducated guesswork. My gf was prescribed Paxil and all it does is mask your emotions to give you the illusion that your feeling less depressed.

This is what I was more concerned about when posting, as the article says

Scientific research has not detected any reliable abnormalities of the serotonin system in people who are depressed.”

and I've never heard this before, so didn't know how accurate it was.



anarchy said:
Therapy should be the number one prescribed thing to treat it. Not medication.

This is what I would suggest, and possibly healthy dieting and exercise.
 
jamie said:
"Imo fear of death (death of the ego, reputation, physical death, spiritual death etc.) is the root of all depression and imbalances in the personality and brain chemistry."

Please go click the links I posted before you post. Everyones depression and anxiety is NOT just due to fear of death etc..things are not that black and white. The relation between childhood abuse/abandonment etc and anxiety/depression is well understood.

If this discussion continues on this way this thread will be locked. This is a serious topic that is going to be relevant personally to some people here and the responces should be better informed than this.

I was abused and abandoned as a child, my Dad was an alcoholic (still is) and used to slap my Mom and my sister and I around & mentally and verbally abuse us just about every night growing up, it's caused me major frustration and depression and anxieties and problems with relationships etc. i still have those frustrations to this day i'm 20 years old. It's just imho i think the fear of death is the collective root problem of all humanities issues and violent/abusive actions. It's just my opinion though.
 
mescaline-man said:
Being diagnosed with a disorder, that's societies latest way of denying it's own illness by pointing the finger at you.

Sorry for posting again i meant to edit the post i had already had up there!

It's okay..and I dont disagree with you entirely. Much of this is at the root a problem with the greater society..but how does that relate back to the individual? that realization is not going to help them, because the damage is already done. Certain chemical pathways are underdeveloped causing a very real chemical imbalance. This does NOT mean that drugs are necessary to build up and strengthen those pathways, though something like ayahuasca or iboga can most likely help in some cases. Working with a skilled therapist, taking time to love yourself and meditate etc..these can all help.

I know someone very very well whos family member was working with Gabor Mate in therapy. Basically everyone in the group was from the downtown eastside Vancouver, abused or neglected at childen..depressed and anxious their whole lives ended up addicted to opiates or other drugs. So I followed this research closely because I knew of his ayahuasca work. Childhood development is a very important in relation to the health of the adult. if the developmental environment is hostile, or one of neglect etc this causes so many problems.

Saying it is just a fear of death, or that a chemical imbalance does not exist etc is just an inadequate explaination here, and in a case like this you need to provide some sort of evidence to support this. I have provided links that can explain some of this, if people read them before posting this discussion could be much richer and we can avoid making generalizations.
 
Okay I hate to point this out, as being the op with the intention of seeking more information, I can’t really have an “informed opinion”

But

jamie said:
Sounds like you have a biased agenda

jamie said:
If this discussion continues on this way this thread will be locked. This is a serious topic that is going to be relevant personally to some people here and the responces should be better informed than this.

Sounds like you have a biased agenda

jamie said:
a biased agenda

Not to be affray, but as the op I’ll say that, I’m intrigued to see all opinions (informed or otherwise), however, uninformed opinions will be criticized and may be dismissed if they don’t hold up to scrutiny 😉
 
Jamie. Your link and the ops link they aren't at all related. Ops link states that a chemical imbalance isn't the cause of depression. Your link states that lower oxy levels were found. Ops post/link is about how the depression isn't caused because you have an imbalance but rather that your imbalance is caused by an event.

If you are beaten by your dad, your body will trigger changes in your chemical balance. Say in your link, lower oxytocin levels. Increasing your oxytocin levels won't get rid of your depression. It may mess up how you feel because your body is saying, hey the mental issue is still there what's going on?

Anyways your link does not disprove his. It actually strengthens it.
 
actaully no this is what that article states..

"a depression chemical imbalance doesn’t exist."

Which is bs.

"If you are beaten by your dad, your body will trigger changes in your chemical balance. Say in your link, lower oxytocin levels. Increasing your oxytocin levels won't get rid of your depression. It may mess up how you feel because your body is saying, hey the mental issue is still there what's going on?"

How does that differ from what I already stated numerous times in relation to people needing real therapy etc as opposed to pharmaceuticals?

This thread is now locked for the time being.
 
jamie said:
mescaline-man said:
Being diagnosed with a disorder, that's societies latest way of denying it's own illness by pointing the finger at you.

Sorry for posting again i meant to edit the post i had already had up there!

It's okay..and I dont disagree with you entirely. Much of this is at the root a problem with the greater society..but how does that relate back to the individual? that realization is not going to help them, because the damage is already done. Certain chemical pathways are underdeveloped causing a very real chemical imbalance. This does NOT mean that drugs are necessary to build up and strengthen those pathways, though something like ayahuasca or iboga can most likely help in some cases. Working with a skilled therapist, taking time to love yourself and meditate etc..these can all help.

I agree i love meditation and paying attention to your dreams helps alot of thing, Therapy may help some, but in most instances that iv'e read or heard about, it just ends up waisting their time and draining their wallet. I would much rather prefer a shamnan :) I want the immediate experience like what Terence Mckenna always says.

I know someone very very well whos family member was working with Gabor Mate in therapy. Basically everyone in the group was from the downtown eastside Vancouver, abused or neglected at childen..depressed and anxious their whole lives ended up addicted to opiates or other drugs. So I followed this research closely because I knew of his ayahuasca work. Childhood development is a very important in relation to the health of the adult. if the developmental environment is hostile, or one of neglect etc this causes so many problems.

Yes i know i started taking after my Dad drinking beer and smoking cigarettes at the age of 12 or 13. It's not easy and the way societies are set up drugs are sadly seem like the easiest option at least on an emotional - society acceptance kind of way at that age.


Saying it is just a fear of death, or that a chemical imbalance does not exist etc is just an inadequate explaination here, and in a case like this you need to provide some sort of evidence to support this. I have provided links that can explain some of this, if people read them before posting this discussion could be much richer and we can avoid making generalizations.

No i'm sure there are chemical imbalances i didn't say that, it's like our bodies natural reaction telling our minds or consciousness that something is not right within us. Imo the mind manifests the physical, even if it's your fault or not, because our brain/mind is like an programmable organic computer.
 
SCHALER: Thank you, Tom. Well, right off the bat I see we disagree. And I see that our opponents are already confusing diseases with behaviors. Now, depression most certainly is not a disease, because depression is a word that we use to describe activity, and activities are behaviors based in values. They aren't physical, they are ways of moving in the world. Now, if by a disease you mean something physiological, if you have a particular way of deciding that a person's brain is not producing enough serotonin, for example, or uptaking enough, or there's a problem in uptake or transmission of serotonin, then perhaps what you've discovered and outlined would qualify as a bona fide disease. In that case, though, you don't rely primarily on activity or symptoms, I beg to differ, a diagnosis is not made on the basis of a cluster of symptoms, it is made on the basis of a cluster of signs. And when we talk about signs in medicine we are talking about physiological lesions, neurochemical imbalances, etc. Depression is not found in a corpse at autopsy, because depression does not refer to anything physiological, it refers to how a person conducts himself, or moves in the world. Thank you.

Taken from Actual scientific debate

There is a debate as to what causes depression. One side of the field views it as a disorder. The other side views it as a normal process of chemical interaction caused by a source outside the body. Physical abuse for example.

Now it is extremely important this thread stays on topic and without negative communication between one another. We all need to agree on semantics in a way as to appropriately discuss the topic so that everyone is on the same page.

This is not a thread about big pharma or about any topics that are not science related period.
 
The bottom line is that we really don't know the full story and its fair to say that the 'neuropathology' of depression (WHICH itself ,IMO, is pretty arbitrarily defined) is alot more nuanced than attributing it to a 'chemical imbalance'.

SSRI increases serotonin and makes people feel better, ergo low serotonin must be the cause is superficial thinking in all its (vain)glory.

Chemical imbalance, certainly nowadays, is IMO a patronising way of 'explaining' depression to the lay people but this doesnt mean its been dispensed with.The man in the street 'just wont understand' the complexities involved so this dumbed-down explanation is still utilised.

SSRIs, to take an example, do work- but only in such a clear-cut fashion in people who are 'properly' depressed- hence the poorer response when these agents are used in a wholesale fashion which renders a shit life as being akin to depression.

We've much to learn but its what happens after the serotonin levels are 'rebalanced' thats been the target of research which may be relevant to the therapeutic effects.Heres a good overview of this; do note that other hormonal systems are also implicated and the large number of permutations of potential interactions of these (and probably other systems too).



I suppose this also allows the question of brain vs mind to rear its head too.

We think we know alot, but of the total sum of knowledge, we have but just an inkling.
 
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