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'di-methyl-tryptamine': DMT

Migrated topic.
There are 2 main chemical families of psychedelic drugs:

The Phenethylamines and the tryptamines, the best known phenethylamine is mescaline, which I'm sure you all know comes from many different types of cactus, MDMA is also in this family.

Tryptamines all possess a nucleus, or basic building block, of tryptamine. Tryptamine is a derivative of tryptophan, an amino acid present in our diet.

Serotonin is a tryptamine---5-hydroxy-tryptamine, although it is not psychedelic it contains one more oxygen atom than dose tryptamine.

DMT is a tryptamine and is the simplest Psychedelic. Simply add two methl groups to the tryptamine molecule and the result is 'di-methyl-tryptamine': DMT.

5-methoxy-DMT, or 5-MeO-DMT differs from DMT by the addition of one methyl group and one oxygen.

Psilocybin is the active ingredient in 'magic mushrooms'. When these mushrooms are ingested, the body removes a phosphorous atom from the psilocybin, converting it to psilocin. Psilocin differs from DMT by onley one oxygen.
Many people like to think of magic mushrooms (psilocybin/psilocin) as "orally active DMT" Interesting to note some other names for psilocybin/psilocin, psilocybin also known as psilocybine or 4-PO-DMT. and psilocin or 4-HO-DMT (4-hydroxyl-dimethyltryptamine). So thay both are dmt, just different:d :d

DMT while chemically simple, this spirit molecule provides our consciousness access to the most amazing and unexpected visions, thoughts and feelings. it throws open the door to worlds beyond our imagination.
DMT exists in all our bodies and occurs throughout the plant and animal kingdoms. It is part of the normal makeup of humans and other mammals; marine animals, grasses and peas; toads and frogs; mushrooms and molds; and bark, flowers, and roots.

DMT is only orally active with an MAOI, otherwise smoke it as I'm sure Ur all aware:d

It is not stretching the truth to suggest that the brain "hungers" for it.

All info and more can be found reading DMT: the spirit molecule
 

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As this is the place for First Questions for Information i figure people can read this for a bit of info. why do u not like it here? My bad
 
I wrote it up from my copy of the spirit molecule, and a little bit was me. despite how pointless u think the original post was its a lot more informative than your posts knocking it.
If you like to identify with your ego a sight regarding dmt probably is not the best place.
 
nn-DreemMasterTree said:
Psilocybin is the active ingredient in 'magic mushrooms'. When these mushrooms are ingested, the body removes a phosphorous atom from the psilocybin, converting it to psilocin. Psilocin differs from DMT by onley one oxygen.

The fascinating thing about the conversion from 4-PO-DMT->4-HO-DMT is that it is catalyzed by the same enzyme that converts ATP->ADP+q, where q is energy. The conversion of ATP->ADP is one of the most important reactions in the human body. Without this reaction we would not be able to function as it is the source of all energy in the body. Basically our body mistakes the P in 4-PO-DMT for one of the Ps in ATP and removes it leaving us with the active 4-H0-DMT.
 
DMT is not the simplest tryptamine psychedelic as far as structure goes AMT looks simpler.
 

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Hi nn-DreemMasterTree,

We have a Wiki for this kind of information, check it out!


nn-DreemMasterTree said:
It is not stretching the truth to suggest that the brain "hungers" for it.
You are making the truth quite elastic with such a wording. ;)


Kind regards,

The Traveler
 
The Traveler said:
Hi nn-DreemMasterTree,

We have a Wiki for this kind of information, check it out!


nn-DreemMasterTree said:
It is not stretching the truth to suggest that the brain "hungers" for it.
You are making the truth quite elastic with such a wording. ;)
:lol: What Trav said...perhaps the statement, "It is the second most actively transported molecule across the blood-brain barrier, after glucose (which provides the brain with energy)," conveys what you're trying to say with a little less distortion.
 
shishigami said:
nn-DreemMasterTree said:
Psilocybin is the active ingredient in 'magic mushrooms'. When these mushrooms are ingested, the body removes a phosphorous atom from the psilocybin, converting it to psilocin. Psilocin differs from DMT by onley one oxygen.

The fascinating thing about the conversion from 4-PO-DMT->4-HO-DMT is that it is catalyzed by the same enzyme that converts ATP->ADP+q, where q is energy. The conversion of ATP->ADP is one of the most important reactions in the human body. Without this reaction we would not be able to function as it is the source of all energy in the body. Basically our body mistakes the P in 4-PO-DMT for one of the Ps in ATP and removes it leaving us with the active 4-H0-DMT.
Rubbish.

There's not a single ATPase enzyme in the body, there's a whole family of them. And ATPases belong to a larger class of dephosphorylase enzymes. You either spell me the name of the enzyme that hydrolyses psilocybin and reference it please otherwise keep the or keep the blah blah at bay.
 
nn-DreemMasterTree said:
If you like to identify with your ego a sight regarding dmt probably is not the best place.
Is this kind of talk really necessary? Are we going to start pointing the ego-finger at each other now?

"You identify more with your ego than me"; "No you do"; "No you do". "I know for a fact that I'm enlightened and you're not"... Where does it lead?
 
Infundibulum said:
shishigami said:
nn-DreemMasterTree said:
Psilocybin is the active ingredient in 'magic mushrooms'. When these mushrooms are ingested, the body removes a phosphorous atom from the psilocybin, converting it to psilocin. Psilocin differs from DMT by onley one oxygen.

The fascinating thing about the conversion from 4-PO-DMT->4-HO-DMT is that it is catalyzed by the same enzyme that converts ATP->ADP+q, where q is energy. The conversion of ATP->ADP is one of the most important reactions in the human body. Without this reaction we would not be able to function as it is the source of all energy in the body. Basically our body mistakes the P in 4-PO-DMT for one of the Ps in ATP and removes it leaving us with the active 4-H0-DMT.
Rubbish.

There's not a single ATPase enzyme in the body, there's a whole family of them. And ATPases belong to a larger class of dephosphorylase enzymes. You either spell me the name of the enzyme that hydrolyses psilocybin and reference it please otherwise keep the or keep the blah blah at bay.


Yea, I just realized what I said was really stupid when I did a bit more reading. It is a similar action but not the same enzyme.
 
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