The main goal appears to be attempting to make a really vague patent in the hope that it may turn out to be profitable somehow. Or, if it's the malate/fructose formulation research you mean, that looks on the face of it very much like a simplified version of ayahuasca for baseline pharmacodynamic investigation, a standardised tool, if you will.
OK. I was thinking of some or other bit of research that suggested plant sugars assisted with alkaloid absorption in ayahuasca - rather like mannose (or mannitol?) assists with psiloc[yb]in absorption, as per some other research.
But, being qualitatively different, would you say it can get as strong for you through both ROAs?
Turns out one of the main components in Ayahuasca brews is fructose. I read a paper about it, I'll find it tomorrow. They theorize it may contribute to the stomach effects. Given the low concentrations of harmalas found in the samples, I don't think anything in particular is needed to make them more soluble in Ayahuasca. Plus they found harmalas in the suspended solids too, so it seems like it wasn't that well dissolved to begin with.
But for example, are you "able" (not that it's usually an explicit goal) of get those feelings of spinning, flying, dizziness, and visual flickering when the light changes from sublingual harmalas? I've never been able to, but maybe I'm not doing it right or waiting enough time before swallowing. It does feel qualitatively different but also like a lower dose (to me).
Some people claims that clear mushroom tea has much weaker effect that tea+mushroom solids. Whole this solubility/absorption topic is quite complicated.
Afaik all these symptoms are mainly sign of ingestion of harmaline, which is subjectively dominant in rue. Do you have it also from caapi?
Makes sense, this is from rue harmalas, yes. I haven't experienced it with caapi, but my experience with caapi is still limited. However I haven't been "able" to experience this from sublingual rue harmalas.
It may be an individual difference then. Or maybe I'm swallowing too soon.
That's pretty vague solubility data! Temperature and amount wasn't mentioned, but I would guess that "slightly" soluble is a bit more than "poorly" soluble, but less than "moderately" soluble. And by inference in comparison with DMSO, where heating is mentioned, I would presume that lack of even a qualitative temperature level for water implies that the test would be at between 20 and 25°C, and by extension kind of suggests that heating may well increase baeocystin's solubility, to stretch it to the maximum extent.
