DMT effect on stroke

[efrecska]

Here is our latest:
Nardai S, László M, Szabó A, Alpár A, Hanics J, Zahola P, Merkely B, Frecska E, Nagy Z.
N,N-dimethyltryptamine reduces infarct size and improves functional recovery following transient focal brain ischemia in rats. Exp Neurol. 2020 Feb 14;327:113245. doi: 10.1016/j.expneurol.2020.113245.
DOI: 10.1016/j.expneurol.2020.113245

N,N-dimethyltryptamine reduces infarct size and improves functional recovery following transient focal brain ischemia in rats - PubMed

Our results indicate a Sig-1R dependent reduction of the ischemic brain injury following exogenous DMT administration in rats, presumably through a combined anti-apoptotic, pro-neurotrophic and anti-inflammatory treatment effect.

www.ncbi.nlm.nih.gov

EF

 

[roninsina]

Thank for your diligence, Ede! Will read after work.
:thumb_up:

 

[efrecska]

Here is our previous one (the target is organ transplantation):
Nemes B, Peto K, Nemeth N, Mester A, Magyar Z, Ghanem S, Sogor V, Tanczos B, Deak A, Kallay M, Bidiga L, Frecska E. N,N-dimethyltryptamine Prevents Renal Ischemia-Reperfusion Injury in a Rat Model. Transplant Proc. 2019 May;51(4):1268-1275. doi: 10.1016/j.transproceed.2019.04.005.
EF