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TEK Ethyl acetate approach [CIELO]

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Which botanics, with a view to recovering which substances? Some will work, some won't, and yet others will require variation of methods, likely to the point of not really being CIELO any more.
You should be able to get many/most alkaloids since most are basic in nature with some exceptions. The issue you may get is salting with citric acid as that alkaloid citrate may or may not be soluble in the ethyl acetate. Most papers do not even attempting salting they evaporate the solvent completely then research as freebase or salt here after solvent is recovered. You could also add an acid water to pull the now acidic alkaloid back to the water.
like transform mentioned at this point it isn’t really even Cielo anymore and just using ethyl acetate as the solvent.

Edit: I replied to the wrong post but still works. :)
 
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Laying out the general principles of what we call CISLO (which has its own thread) we have: base treatment of plant material in paste form; solubilisation of freebase alkaloid in broadly water-immiscible NPS; salting of alkaloid with at least weakly NPS-soluble acid; formation of NPS-insoluble alkaloid salt ideally in crystalline form (DMT citrate forms an oil, just as an example of other possible outcomes).
Search: [threads] CISLO

A three-dimensional (at least) spreadsheet would be required for comparing combinations of alkaloid, NPS and acid. Sounds like fun 😁
 
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