First time doing Mescaline. Any advice? Might add DMT as well

[Prima Materia]

Great to hear the experience went well! The slow build up of effects with mescaline is nothing to ignore that's for sure. For me it takes about 3 hours to fully develop from single dose, what to speak off redosing.

 

[TransistorBass]

It's much riskier today, and you need to test beforehand, especially due to fentanyl. Stay safe

Pretty much Medical Weed and DMT only for me, I feel like I've grown out of the silly stuff done in the 90's. Had some great, and silly times but happy to leave those 30 years ago.

 

[ommani]

Watchout for headaches or migranes. This is the one issues that prevents me from taking mescaline or cactus. I would recommend having some anti-inflamatory pills on hand in case you sense a headache developing. For me it usually starts slowly building up when the peak ends and the plauteu begins. The headache reaches hardcore migraine levels at night following the experience. I think it's better to take a naprosin or two than having to deal with the pain and potentailly vomiting from pain. It might not happen to you, but I thought I should at least mention it to be prepared.

Enjoy your ride!

This has been my experience, even at low doses of cactus (maybe equal to 100-200mg of mescaline). Taking some psilocybin cleared away the headache, the one time I tried it. Might take some ibuprofen next time, as needed. Cactus/mescaline is so great, so it’s unfortunate that it can cause these extreme headaches.

 

[manifest_jynx]

This has been my experience, even at low doses of cactus (maybe equal to 100-200mg of mescaline). Taking some psilocybin cleared away the headache, the one time I tried it. Might take some ibuprofen next time, as needed. Cactus/mescaline is so great, so it’s unfortunate that it can cause these extreme headache

You know that's the one thing I didn't get was a headache and I hear that's really common... I did have synthenic mescaline HCL tho so I didn't get any extra alkaloids from the cactus. Just the Mescaline itself. Maybe that had a effect on why I didnt get headache?
I'm even a super migraine prone person and I barely got any signs of a headache

 

[Prima Materia]

You know that's the one thing I didn't get was a headache and I hear that's really common... I did have synthenic mescaline HCL tho so I didn't get any extra alkaloids from the cactus. Just the Mescaline itself. Maybe that had a effect on why I didnt get headache?
I'm even a super migraine prone person and I barely got any signs of a headache

Some people are very prone to mescaline headaches and other not. From what I have read and what I had experienced it has to do with mescaline rather than other alkaloids.

 

[manifest_jynx]

Some people are very prone to mescaline headaches and other not. From what I have read and what I had experienced it has to do with mescaline rather than other alkaloids.

Interesting. I'm glad I didn't get a headache because that would have just ruined my whole experience