First time mescaline trip: k-valle Bridgesii

[liucha]

Hey all,



I reduced two 12 inch 'K-valle'Bridgesii cuttings that were grown outside in the SoCal sun their whole lives by a sustainable, reputable grower.



I wanted to try the full alkaloid profile of the cactus for my first time. I made some resin and rolled it into little balls. I can detail my extraction method if requested but it was my first time and I doubt it was anything unique or special.

I'm realizing now that I jumped the gun and didn't measure how much cactus powder I made from my dehydrated cactus cuttings. I did take a photo of the dried stars before I powderized them, so maybe that can give some experienced folk a general idea. I was guessing anywhere from 30-60 grams, lol.

As I stare at this resin, I am realizing I have no way of knowing what the dose will be if I eat it all. Im not really scared of an intense, scary trip because they're usually meaningful in the end.

The variability is wild on it's own with the alkaloid profile variations and potency variations in these cacti. But since I didnt measure initial powder, I feel its just chaos now

Its so weird to me that I could be staring at a massive dose I may regret taking all at once a bit, or a bunk pile of caramelized sugars, fats, etc.


I was wondering if anyone with more experience than me could approximate a likely dose based on the photos and normative potency levels of Bridgesii.

 

[doubledog]

I would start with eating 1g of the resin to estimate its potency.

 

[liucha]

I would start with eating 1g of the resin to estimate its potency.

Yeah thats probably the smart thing to do. Thank you for the input, it really helps!

Ill have to temper my urge to just send it and see what happens. Ive had some hellish, powerful trips but this is a new cluster of molecules I've never tried.

Do you think, if 1g is weak (like barely noticeable effects), taking a booster dose with the remaining resin will even be worth it? Ive read that since these alkaloids are mostly hydrophillic, they take forever to cross the blood brain barrier and do brain stuff. Im worried about having a really meh peak if its weak and I split the doses. I think its a sunken cost thing; this little project was 2 weeks total from procurement of the cuttings to final resin balls.

 

[doubledog]

Yes, mescaline/cactus can be taken that way, in splitted doses. It's even common way to do it like that.

Cactus is slow, so if you want, take 1g (or maybe 2g), wait 2 hours and take the rest if effects are not satisfactory.

Imo you could eat it all in one dose, but bridgesii could be quite harsh physically, so would be better to start lower just to test the water.

 

[liucha]

Yes, mescaline/cactus can be taken that way, in splitted doses. It's even common way to do it like that.

Cactus is slow, so if you want, take 1g (or maybe 2g), wait 2 hours and take the rest if effects are not satisfactory.

Imo you could eat it all in one dose, but bridgesii could be quite harsh physically, so would be better to start lower just to test the water.

Thanks man I'm excited! Based on what I've read, this stuff has a unique signature and I cant wait to see what I think of it.

 

[doubledog]

Yes, mescaline is quite unique. Imo it requires your mental activity or cooperation during the trip, in small or medium doses it's not so ovewhelming or immersive as mushrooms.

 

[liucha]

Yes, mescaline is quite unique. Imo it requires your mental activity or cooperation during the trip, in small or medium doses it's not so ovewhelming or immersive as mushrooms.

And see I think that less overwhelming aspect could be super beneficial for a lot of people i imagine. Thats what I am the most curious about.

 

[doubledog]

Absolutely agree, cactus would be very beneficial for lot of people. I believe that in near future, cactus will become much more popular.
It has MDMA-like empathy, which could be beneficial for most of modern people.

 

[liucha]

Absolutely agree, cactus would be very beneficial for lot of people. I believe that in near future, cactus will become much more popular.
It has MDMA-like empathy, which could be beneficial for most of modern people.

Honestly to me I see it as an incredibly unique psychedelic. Im a bit of a psychopharm nerd, and it has a really low affinity for other serotonin receptors besides the good ol' 5HT2-A receptor, which is probably why its a bit less chaotic mentally than psilocybin.

But beyond that, its dopaminergic and noradrenergic receptor (weak to moderate) affinity is fascinating. On paper it absolutely looks like the best of both worlds, and probably a lot gentler than both MDMA (which I believe is basically just a phenethylamine crammed together with methamphetamine) and psilocybin. It should have a pretty good amount of salience.

According to the literature on 5HT2-A agonists and neuroplasticity, it should still trigger mTOR signaling and BDNF increases in the brain like any other 5HT2-A agonist fairly reliably. I see a future for mescaline in psychedelic assisted therapies that involve groups, trauma, or folks with super high anxiety/neuroticism. Im curious to see if it obliterates my default mode network like psilocybin or LSD does.

This extraction has made me fully and completely realize why it isnt available anywhere my goodness! So much work for, probably, one dose. And NO guarantees that your work will even yield that due to cactus potency variability.

But its been a fun project that I have to admit, I kind of miss already. Nursing the tea through so many boils and reducing the resin carefully was super fun in the end.

 

[blig-blug]

It does have an aspect similar to MDMA, but it's much weaker and IMO not comparable. On the other hand, it's a psychedelic and MDMA isn't.

Makes sense that it's not as strong, because MDMA is a strong serotonin releaser and mescaline isn't. On the other hand, that makes mescaline safer and possible to dose more often without neurotoxicity.

I'm also quite impressed with mescaline, which I've tried recently for the first time. I wonder how it would be if combined with MDMA, timed so that the come-up starts as MDMA begins to fade. In a similar way as it's done with 2C-B. IMO mescaline is superior to 2C-B in almost every way, they are not even in the same league.

I don't have a specific point here, just some thoughts

 

[neurobloom]

Francly i noticed no difference between IPA resin and DCM acid base extract..

Nothing alcohol resin can offer that a wide spectrum solvent in an acid base cannot provide. Alcohol resin only adds nausea.

 

[Jamie01]

Peyote has more of the mdma like empathic quality in my experience compared to trichocereus. I have not tried every trick out there however and overall peyote is still mostly a mescaline trip. It does contain a lot of other phens however. It also seemed more visual than most trichs.

 

[SkunK]

I would definitely be interested in hearing your Cacti Resin preparation, And trip report.

I have a nice cutting I will be prepping for a journey and would like the full spectrum experience. Not too keen on tea as it usually makes me violently nauseous and I hear the resin doesn't leave a heavy body load on the guts.

I have been reading up on this tek on the forums and its probably pretty close to your methods I'd assume

Thread 'Resin. The way to go.'

Oct 26, 2009

Did you know you can evaporate your filtered san pedro tea (ie: oven@150F or food dehydrator) to yield a resin that is easily scraped up with your fingers and rolled into capsules? (It has a Taffy-like consistency)

This resin is far superior to pure extracted mescaline.

There's so much more to it...you gotta see for yourself.

This is golden, glowing, soul food.

You can get far more out of your cacti this way.
Just simply simmer or crock pot your pedro chunks (sliced like food) with lemon juice for as long as you want.

What my friend does is simmer the pot for 5 hours, the freezes it...

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• Forum: Preparation

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[Jamie01]

Once I made balls with cacti resin and flour and ate them at a music festival. It was a long night of intestinal distress. Worse than a tea. I’m certainly not a good example of a normal gut but I never felt cacti resin to be as clean as an actual extract.

Mescaline is just about the best psychedelic when I get it right but it sucks how those teas etc effect my guts.

 

[SkunK]

Once I made balls with cacti resin and flour and ate them at a music festival. It was a long night of intestinal distress. Worse than a tea. I’m certainly not a good example of a normal gut but I never felt cacti resin to be as clean as an actual extract.

Mescaline is just about the best psychedelic when I get it right but it sucks how those teas etc effect my guts.

W
What kind of Extract are you talking ( HCL) ? I've got a few grams of HCL and have been itching for a full spectrum extract, possibly redosed with some HCL salts mid trip. HCL is one of my favorites and I never get and gut distress. Never any nausea either but its lacking some of the other good in the cacti.

I do have a weak gut as well, and when eating mushrooms I get the worst distress ever! I prefer a 90 Proof moonshine extract and discard the mushrooms to have an easier time usng medium to heavy mushroom trip.

I know cacti tea always is accompanied by the purge, last time was pretty traumatic, I didn't have time to make it and gave the cacti and directions to make the tea with a buddy, and I got back a liter of what tasted like pure vinegar to chug back..... there was a lot to purge for everyone. I should have made the tea in hind site, but I was busy at work at the time.

 

[Transform]

I wanted to try the full alkaloid profile of the cactus for my first time.

Slowly munching slice after slice of fresh cactus will give you that Buccal absorption of cactus alkaloids seems likely too.

Nursing the tea through so many boils and reducing the resin carefully was super fun in the end.

It really is a beautiful process isn't it? I feel exceedingly fortunate in having had the opportunity to brew in a private stone circle (not ancient, but that's a minor concern) and incorporated various herbs from the surrounding garden. Some very positive feedback was given regarding that brew. With a certain amount of luck and the right cactus, it's even possible to get it nearly palatable. But only nearly

Slow and gradual intake of the desired dose has brought good results for me, and seems to fit well with the protracted duration that mescaline offers anyhow. I've not used concentrates like resin - I've either sipped fairly (but not overly) dilute brews or, as mentioned before, just eaten thin strips of fresh material whittled straight of a handily portable chunk.

If any of this makes you change your mind about the resin, you could always dilute it back down with hot water and filter out any insolubles, I suppose.

Be warned, I'm not at all bothered by very bitter tastes, although my regular consumption of wormwood tea actually started after these cactus sessions. If that's a bother for you, get training with bitter salad leaves like radiccio, endive and chicory.

As a kind of reference, Shulgin did mention that it was often reported as being far gentler on the guts to take multiple small fractions of the total mescaline dose rather than the whole lot at once, and my observations essentially confirm this after their own fashion.

 

[liucha]

It does have an aspect similar to MDMA, but it's much weaker and IMO not comparable. On the other hand, it's a psychedelic and MDMA isn't.

Makes sense that it's not as strong, because MDMA is a strong serotonin releaser and mescaline isn't. On the other hand, that makes mescaline safer and possible to dose more often without neurotoxicity.

I'm also quite impressed with mescaline, which I've tried recently for the first time. I wonder how it would be if combined with MDMA, timed so that the come-up starts as MDMA begins to fade. In a similar way as it's done with 2C-B. IMO mescaline is superior to 2C-B in almost every way, they are not even in the same league.

I don't have a specific point here, just some thoughts

Maybe. Itd be safest to make sure its PURE mescaline, because based on some research ive been reading, some of these cacti contain other alkaloids like Hardinine that are relatively potent MAOIs - probably the worst class of drug you could combine with MDMA. Very dangerous.

 

[liucha]

As a kind of reference, Shulgin did mention that it was often reported as being far gentler on the guts to take multiple small fractions of the total mescaline dose rather than the whole lot at once, and my observations essentially confirm this after their own fashion

That is very interesting! I wonder if its less of a blitzkrieg on the gut's 5HT3-A receptors when you ingest this way, reducing the nausea. My plan is to eat some raw ginger 40 mins before to inhibit some of those receptors, but maybe ill titrate the dose alongside that to further hedge against nausea.

As for the rest of your comment, I was debating 2 alternatives: finish dehydrating to a glass texture, powderize, put in capsules, take as pills.

Orr, like you said, rehydrate the resin to about a cups worth of liquid and just drink it in quarters.

Part of me is so eager to take this stuff that I am probably just gonna swallow these little resin balls im so ready. Ive taken a few days to reduce my caffeine intake. My plan is to take it on a paid day off I took (will have the house to myself for 10 hours) right away in the morning. No nicotine or caffeine during the come up to reduce somatic nervous system load. I want this to be as clean as possible.