didn't realize I started this thread. :surprised
looking around on e.bay, I found this
I have one, it is an Omni International GLH (general laboratory homogenizer) 750W rotor-stator homogenizer, which works wonders for breaking down dried materials and cells. Very useful for what we're trying to do here. Rotor-stators and ultrasonic homogenizers (even the baths), are great for getting the alkaloids into methanol or your solvent of choice; quicker than a soxhlet, but you could even do that afterwards.
I honestly think some column work is essential for this project. I know there exists a solvent-partitioning method, pioneered by Hoffman, but it seems like more of a hassle. Column work with a ternary (or quat) mobile-phase readily separates out psilocybin, and psilocin, using acetic acid. I'll look into simplifying it, as I've already shown the separation occurs using HPLC.
looking around on e.bay, I found this
I have one, it is an Omni International GLH (general laboratory homogenizer) 750W rotor-stator homogenizer, which works wonders for breaking down dried materials and cells. Very useful for what we're trying to do here. Rotor-stators and ultrasonic homogenizers (even the baths), are great for getting the alkaloids into methanol or your solvent of choice; quicker than a soxhlet, but you could even do that afterwards.
I honestly think some column work is essential for this project. I know there exists a solvent-partitioning method, pioneered by Hoffman, but it seems like more of a hassle. Column work with a ternary (or quat) mobile-phase readily separates out psilocybin, and psilocin, using acetic acid. I'll look into simplifying it, as I've already shown the separation occurs using HPLC.