How much purification do Rue harmalas actually need?

[awalmartbag]

I have been thinking... if it is to be taken orally, how important is it to get high purity harmine/harmaline? I figure not terribly, since some just drink Rue tea without any extraction/purification.

Can I just use the light brown precipitate that one gets after 2-3 A/B cycles? Maybe adjust the dosage by a factor of 2 to account for impurities?

 

[Transform]

Can I just use the light brown precipitate that one gets after 2-3 A/B cycles? Maybe adjust the dosage by a factor of 2 to account for impurities?

Don't double the dose, there will be far less than 50% impurities and doing so will risk causing a challenging level of debilitation.

 

[blig-blug]

From a safety standpoint, not important. You may find information stating that it's desirable to get rid of vasicine and vasicinone because they are toxic. That information is outdated, they aren't toxic or dangerous at all at regular doses, with the exception of pregnant women, who should avoid them because they are uterotonic.

Purification matters more if you want to be exact with your doses and minimize any additional variables, or if you intend on vaping.