anabolic_hippie
Rising Star
does anyone know how long someone has to be off oxycotin before they can do ayahuasca, i know with anti depressants its 3 weeks but its not that long for oxys i believe or is it any help would be apperciated
Du57mi73 said:I read your title and thought you combined oxytocin(not oxycodone/contin) and aya. I was intrigued.
anabolic_hippie said:does anyone know how long someone has to be off oxycotin before they can do ayahuasca, i know with anti depressants its 3 weeks but its not that long for oxys i believe or is it any help would be apperciated
The activity of OxyContin is primarily due to the parent drug oxycodone. OxyContin is designed to provide delivery of oxycodone over 12 hours. [..]
Oxycodone is extensively metabolized and eliminated primarily in the urine as both conjugated and unconjugated metabolites. The apparent elimination half-life ( t½ ) of oxycodone following the administration of OxyContin was 4.5 hours compared to 3.2 hours for immediate-release oxycodone.


anabolic_hippie said:sorry i dont understand your reply yeah math - not even once
The activity of OxyContin is primarily due to the parent drug oxycodone. OxyContin is designed to provide delivery of oxycodone over 12 hours. [..]
Oxycodone is extensively metabolized and eliminated primarily in the urine as both conjugated and unconjugated metabolites. The apparent elimination half-life ( t½ ) of oxycodone following the administration of OxyContin was 4.5 hours compared to 3.2 hours for immediate-release oxycodone.
The biological half-life or elimination half-life of a substance is the time it takes for a substance (for example a metabolite, drug, signalling molecule, radioactive nuclide, or other substance) to lose half of its pharmacologic, physiologic, or radiologic activity, as per the MeSH definition.
7.4 Monoamine Oxidase Inhibitors (MAOIs)
Monoamine oxidase inhibitors have been reported to intensify the effects of at least one opioid drug causing anxiety, confusion, and significant depression of respiration or coma. The use of OXECTA is not recommended for patients taking MAOIs or within 14 days of stopping such treatment.
SkyKitty said:I agree with the good advice given above. Mixing ayahuasca and opiates is dangerous. It would be foolhardy to play doctor and/or shaman in this situation.
If your friend is hooked on pain pills, you should encourage them to go to rehab and be in the care of experts, medical experts! After that process, if existential questions still remain, then maybe ayahuasca is a good idea. But only after. More drugs do not, and cannot, cure drug addictions.
Also, having had multiple friends lose themselves in the world of addiction, it is always better to express your concern and support for their wellness sooner than later. The longer we wait, the worse these situations can get!
SkyKitty said:But only after.