Ph will not go higher

[downwardsfromzero]

My guess would be that you crashed a small amount of sodium (dihydrogen) citrate because of the common-ion effect. Presumably the amount was too small for any kind of analysis.

Great idea with the co-administration - I wonder if any other anions, organic or inorganic, will have an enhancing effect.

 

[Loveall]

My guess would be that you crashed a small amount of sodium (dihydrogen) citrate because of the common-ion effect. Presumably the amount was too small for any kind of analysis.

Agreed, I tasted the small amount that precipitated and it was indeed citric-like and not bitter at all.

 

[Loveall]

Any other bioassays for mescaline benzoate?

Since mescaline benzoate requires extra work (so far), how about doing a bioassy with mescaline citrate, but adding benzoic acid to the mix? DWZ discusses possible effects from benzoic acid metabolism here.

For example, take 300mg of citrate (or equivalent HCl, Sulfuric, etc) together with 300mg of benzoic acid. Is a potentiation noted?

Maybe it's a dumb idea, but easy to try.

I took 600mg of mescaline citrate with 500mg of sodium benzoate. No difference noted compared to mescaline citrate alone.

 

[downwardsfromzero]

Ah well - great that you tried
How exactly did you take the two compounds? Maybe pre-mixing in solution would allow the mystery magic interaction to take place Are there any specifics from the tiny handful of mescaline benzoate that might inform us in some way about the suspected potentiation? Or could it be the positions of the planets, or even a load of misapprehended coincidence a.k.a. "bollocks" in a certain vernacular?

 

[Loveall]

Ah well - great that you tried
How exactly did you take the two compounds? Maybe pre-mixing in solution would allow the mystery magic interaction to take place Are there any specifics from the tiny handful of mescaline benzoate that might inform us in some way about the suspected potentiation? Or could it be the positions of the planets, or even a load of misapprehended coincidence a.k.a. "bollocks" in a certain vernacular?

I put each compound in separate gelatine caps and took them all together.

 

[downwardsfromzero]

Stomach acid would favour absorption of benzoic acid over mescaline because of protonation from the acidic environment...

But why should this differ over simply taking MescH⁺BzO⁻?? :? Does the benzoate perhaps remain insoluble in stomach acid and pass into the small intestine more efficiently? Is some peculiar form of molecular interaction taking place in the MescH⁺BzO⁻? It's time to review the reports - but what we really need is a randomised, double-blind trial.

We seem to have strayed off the thread topic a bit, btw