About grasses:
Indole alkaloids are responsible for toxicity of
Phalaris pastures to sheep and cattle [l-3]. Several of these alkaloids are present in various species of Gramineae, Leguminosae and other plant families [4]. Simple indole bases such as 3-N,Ndimethylaminomethylindole (gramine)
5-methoxy-N,N-dimethyltryptamine (MOM2T, 2), 5- methoxytryptamine (MOT, 3) and N,-methyltryptamine (MT, 4)
...total alkaloid content varies between 0.02-1.19 of dry wt in Phalaris arundinacea [7]
and gramine concentration may reach up to 7 mmol/kg fr. wt in barley ,
..Several plant secondary metabolites are thought to protect plants against insects and patho- gens. For example, hydroxamic acids from Gramineae have been suggested to protect wheat and maize against the European corn borer.
Always known for the property of selectively chelating metals, forming stable products especially with Cu2 +, Fe3 +, V5 +, UO22 +. They have also been studied for the realization of polymer chains with chelating properties to be used in the selective removal of heavy metals [2] [3] Some hydroxamic acids such as SAHA, Vorinostat, PXD101 and Belinostatin, LAQ824 / LBH589 and Trichostatin A, are HDAC inhibitors with anticancer properties.