Plant based Anti-depressants

[joedirt]

The single best antidepressant mixture I have devised yet is this.

1 handful b. caapi leaves
1 tea bag Yerbe Mata
1 tea bag Coco Mata

I put the caapi leaves in a tea pot and boil for a few minutes. I then filter the caapi leaf water into a cup with the coco and yerbe tea bags. I need to get some tea bags for the caapi as well and then I can just make tea. Gonna order them now actually.

Why this works?

Obviously caapi is helping with the brains serotonin health, but the 11 or so different alkaloids in the coca plant have various properties as well. One of them being that cocaine is sort of the SSRI of the dopamine/norepniephrine world. So your brain gets a pretty solid boost of it's core neurotransmitters. Yerbe Mata has a little bit of caffiene which helps to kick eh brains dopamine/norepinephrine system into gear....while the cocain helps it stay in gear.

This mixture puts me in a highly motivated, focused, calm state of mind.

I take this mixture for work a few times a week.

 

[DebajoDeLaLuna]

It surprises me that Peganum harmala (Syrian Rue) has only received passing reference in this thread. P. harmala has a storied ethnobotanical use among the peoples of the Middle East, Mediterranean Europe, and North Africa. Traditionally, use of the Syrian Rue seeds was to counteract casting of the Evil Eye. Local beliefs upheld that the effects of being looked upon by the Evil Eye were symptoms synonymous with depression.

I've been planning on testing harmel seeds with LOW doses of Morning Glory seeds. Morning Glory seeds at low doses should hypothetically cause threshold euphoria (75-100 seeds). I would limit the Convolvulacean "happy-plants" to only Ipomoea or Rivea. Hawaiian Baby Woodrose Seeds are TOO potent. (This may prove untrue if one obtains a weaker variety)

In the next few months I plan on documenting my personal use of the above combination, so be on the look-out for my write-up.

 

[nen888]

..good point DebajoDeLaLuna..the idea of the thread was for different nexians to nominate good candidates, and pool the growing collective knowledge, so thank you, and look forward to hearing of your work with it..
..i've come across various middle-eastern medicinal and ritual uses of P. harmala, certainly the tea is sedative and has the right sort of alkaloids..it also has vascine, absent from caapi..it would be good to compare the two in micro-dosing..
.

 

[SKA]

I don't believe anyone's mentioned Kanna (Sceletium tortuosum) yet.
It's a South african plant that is a natural source of SSRI's (Selective Serotonin Reuptake Inhibitors)
SSRI's are known to have anti-depressant effects making the amount of Serotonin in the brain rise.

I bought a little bag of Kanna powder once. I think it was just pulverised plant. I took
little pinkies of it throughout the day. It produced a very warm, joyfull kind of mood.
Made me rather giddy, prone to laugh. Felt emotionally light and elevated.
Allthough subtile, very definite effects.

It being wintertime again I could use some anti-depressants too. Might pick up some Kanna soon.
Would also be very worthwhile to grow.

 

[nen888]

..thank you SKA, i'd completely overlooked this plant..hmm, contains Mesembrine.. it's added to the list (p2) ..
some good info. on it here: Sceletium.Org - Information and links on Sceletium tortuosum
.
[EDIT: and thanks joedirt for the above formulation..]

 

[nen888]

..it seems the orthodox pharmaceutical world may be ahead of the herbal world in terms of skin-applied anti-depressants..from CNS Spectrums | Cambridge Core

Two recent developments appear to mitigate the risk of tyramine reactions with MAOIs. First, inhibitors have been developed that are not only selective for MAO-A, but are also reversible. Second, an MAOI can now be delivered through a skin patch, resulting in inhibition of both MAO-A and MAO-B in the brain, but with much less MAO-A simultaneously inhibited in the gut. While neither of these innovations enhances MAOI efficacy, both reduce the risk of a hypertensive crisis with ingestion of tyramine.

..further experimentation in skin based delivery of anti-depressant plant extracts (perhaps with DMSO or nitrogen mustards) may also improve our ability to create skin-absorbed entheogens, something only isolated success has ever been achieved in..
.

 

[arcanum]

nen888 wrote:
..further experimentation in skin based delivery of anti-depressant plant extracts (perhaps with DMSO or nitrogen mustards) may also improve our ability to create skin-absorbed entheogens, something only isolated success has ever been achieved in..
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Nitrogen mustards????? (shudder) no way would I ever use that as a delivery facilitator, cytotoxity and chemical warfare spring to mind.

Wouldn't sublingual Salvia divinorum be classed as a type of skin absorbation? ( mucous membrane )

Massage oils infused with Hypericum perforatum have been in use since antiquity. The aromatherapy practice of essential oils relys also on skin, anally administered routes.

 

[nen888]

..get out your gas masks! ha, ha..no, i didn't mean 'mustrad gas' (chlorine), but the so-called Chinese 'nitrogen-mustards' which can allow compounds to be directly absorbed through the skin into the bloodstream..other substances which do this include DMSO (dimethyl-sulfoxide) and oil of Wintergreen..
there was a little experimentation in the '90s making entheogenic 'salves' or 'flying ointments' using the above mixed with DMT etc, but no one could get really strong effects..different carriers have different efficiency in carrying things through the skin..
certainly, mild or 'buzzy' effects have been achieved by mixing DMT with DMSO and rubbing on the skin..but i don't think much experimentation has actually been done..
tropane alkaloids are the most easily skin-absorbed, but are obviously a lot more toxic than DMT, LSA etc..
.

 

[corpus callosum]

WordPress Support

WordPress is ECU's official content management system for college, school and department websites and is also used to house online information for personal and group websites like research, clubs and courses.

blog.ecu.edu

I found this article rather interesting although strictly speaking, we are probably talking about agents which may not be wholly plant-derived.The hazards of this class of compound is well-known, but undoubtedly they do have significant mood-elevating effects.At least in the short-term......

 

[bomshiva]

Cannabis sativa/indica
coca
rue has worked somewhat in the past for 'lifting the viel' off of depression (which is not surprising because they used to perscribe maois for depression)
tulsi -- subtle
ginseng
ashwaganada -- can repair neurons
yerba mate/guayusa/asian tea/ whoahhhh dmt hit


herbs certaintly aren't a cure all though. I would look into exercise, diet, sweating, breathing, meditation etc for relief. hata yoga can be great for depression

 

[sidefx]

It is mushroom season here with me.

And i have started experimenting with myself, as i suffer melancholy and depression often.

i have never tried medication for this.


BUT i have started dosing myself on 100mg of dried psilocybin mushroom after waking up.

AND it works perfect.

Elevated mood, energy, i feel present, clear head, tuned in, witty, feel really goood.

***
it took a week for the effects to last all day, every day.

I chew and suck the shroomfor 5-10 mins before swallowing.

I found that 100mg is fine, 300mg gets me real happy all day joking around with any one LOL.

I notice my body temperature raises.

NOTE this 100mg dose is barely a cap of a small bullet mushroom.

I am a little sensitive to mushrooms, after taking a very large dose a few years back in-midst of a health binge. Harry hero.

It takes a gram (1000mg) usually for me to start tripping.

It is a miracle.

I am writing again and not slouching around, praise....the fungi God

 

[MelCat]

Have you noticed any kind of tolerance build up from the daily dosing or does 100mg daily seem pretty effective no matter the dosing frequency?

 

[sidefx]

I did it for 2 1/2 weeks and it worked better over time, less bothered me.
The first 4 days i had moments of mundane creep in but i shook them off.

I stopped for 4 days, and when i re-dosed with the 100mg it was like taking 300mg?

Does any one know if Mushrooms are addictive in any way?

i felt pretty good the 4 days without mushroom. No craving at all, i had shrooms in case.


**I read an article about in Europe; they have had trials with psilocin mushrooms, on regular people, and up two one year later some of the patients were still mentally effected in a 'Very Positive Direction'.

 

[nen888]

^..psilocybin was recently legally trialed and found to be very successful in post-traumatic stress disorder..because past methods weren't working..e.g. the us army psychiatrist treating soldiers returned from Iraq for post-traumatic stress..he became so disturbed he opened fire on a dozen people in the army hospital base!:x

..as decreasing light can increase feelings of depression, i've bumped this thread for those heading into the colder seasons..to help warm you up..i'd better find some new info to add, i guess..

thanks all the great contributors in the thread..!
some great people in here..
.

ps. for when it gets warmer again..i find looking at Sunflowers makes me less depressed most days..nice cooking oil too..

 

[tango]

Sidefx, are you still taking the 100mg daily dose of mushrooms?

 

[phyllode]

I don't know if shrooms daily Is so good. dmt or huasca sure, even salvia, but I'm not sure about shrooms, hmm.

Awesome Thread! Cheered me up:d . I Love Magnolias. I have a variety growing called 'Starwarsica'. It's flowers look like one of those space ships in the original film! Kava good for stress and anxiety. Though, not needed daily. Maybe every few if you're tense.

 

[nen888]

M. 'Star Wars' (M. campbellii x M. liliiflora): One of the finest magnolia varieties available. ‘Star Wars’ is a large growing vigorous tree to 5 m that bears masses of scented large pink flowers in spring, often repeating the flowering in summer.

..from a plant shop..
..i'm glad the pic of sunflower-man finally uploaded properly..the force is with him!
magnolias..mmm...tea gardens...:want:
.

 

[Jarl Von Hoother]

Baicailin: a polyphenolic extract from skull cap serves as antidepressant, anxlyotic, sedative you can buy on the internet.

Magnolia tree bark alkaloids, Honokiol and Magnolol (widely used in Japan to boost immunity and inhibit cancer cells which an ORAC antioxidant level of upto 1000 times greater than vitamin-E ) even has anti-anxiety, calming effect on the nervous system as well. find it on the internet.

L theanine, amino acid that stops stress in it's tracks by penetrating the blood brain barrier
with gaba releasing agent thereby modulating neurotransmitters in the brain, the brain recedes from beta oscillation into the alpha and a much more calm, comfortable, more intelligent mind state follows.
increases IQ, prevents stress, great for mood. find it in a store or try the internet.

5 htp, serotonin precursor our bodies need the right balance of sertonin, and if you have some out of the ordinary eating or sleeping patterns or you feel sad or lost in anyway try taking 5 htp. find it in a store

even though this is not a plant, if you have serious anxieties I recommend Phenibut a non toxic molecule which works binding to the gaba receptors, one of which benzodiezapines does the same thing. Phenibut is also a great nootropic especially protecting cell membranes and increases dopamine levels. find it over the internet

Hordenine hcl, a mao-b inhibtor, it releases over the day enough dopamine and serotonin to you feel energized and somewhat confident all day. buy it on the internet

rhodolia rosea, also a an maoi, has rosarin which wards off stress and raises neurotransmitters in the brain. buy it on the internet

damiana, dagga somewhat intoxicating both legal substitutes for marijuana
chamomile aerial pieces have chalming effects
lemon balm increases calm sustained focus
valerian root works also
simple b 12 vitamins have a great impact on your diet (if you are depressed, anxious etc.. it could mean you aren't eating enough leafy vegetables in your day, besure to do that)
rosmary

Even the incense you burn has specific ions that act as antidepressants, activate reward complexes in the brain. especially frankincense or myrrh

turning off the tube and going for a jog will make you feel great, anything where thought is tied into action.

drinking enough water, even if you aren't crippling over in a desert exactly because our bodies being 70% water and our brains being 80% also its safe to say you need it

if it's a cold night take a hot bath... which immediately comforts you, causing that alpha brain state i mentioned earlier

'SAM e' causes methylation inside the body helps genetic RNA encoding, but also helps breaks down or helps build molecules like dopamine buy it in the store.

L phenylanine and L tyrsoine are precursors to achieving higher levels of dopamine
DLPA does a little of that and creates more endogenous opiates in the brain. buy it on the internet

smoalking marijuana would also be great.

ayahuasca would be also... as ayahuasca is a blend of maoi's (which should not be taken with ssri's) it contains DMT too which both act as a catalyst for a good deeply introspective night.

I HOPE THIS HELPS SOMEONE
thank you, sincerely

The Jarl

 

[phyllode]

Does anyone else (other than SKA) have experience with Kanna? I'm curious and haven't tried it.

Star Wars flower>

 

[DoctorMantus]

Browsed through this and definitely some great info.

I had seen Aswagandha, but did not see this combo of 3 that i came across a while back but this thread reminded me of it.

Three natural herbs that work together to aid your body's natural defense against anxiety. Ashwagandha, L-Theanine and Passion Flower have been clinically proven to boost GABA and serotonin levels in the human body. The result? You're more relaxed. Worries don't seem as big. Anxiety disappears. And over time,they help to calm your body's natural response to anxiety so you can feel like yourself again.

Studies have shown that these natural ingredients can stimulate the production of GABA and serotonin in your body so worry goes away and you feel calm and anxiety-free.