Salt conversion

[antichode]

My goal is to convert mescaline citrate into HCL and also some sulfate. I have ph meters so I can do this manually but I beleive it can be calculated accurately.

Can someone explain to me how to calculate this. With a known quantity of mescaline citrate (very pure). How do I calculate the amount of base needed to freebase mescaline and then the exact amount of acid needed for the salt?

 

[Varallo]

You can calculate the required amounts of reagent based on molecular weights and stoichiometry, in my experience Chat-gpt is very handy for this.

On a more practical note I would say that you can’t really go without using an pH meter. Volumes, concentrations of acid, conversion of the citrate to the freebase and then moving it into the non-polar fase all have some variation making it very unpractical to go blind without an pH meter.

 

[pete666]

You can find my simple HCL Titration Calculator in Excel in this thread . It is very easy to see the calculation and understand the principle. Should be easy to change it for any other acid. ChatGpt seems to fully understand sent printscreen of the excel sheet and knows what to change when asked.
I don't think it is important to know exact amount of the base, use rather more than less. What is important is the acid. I calculate it in the calculator and then titrate it with nitrazine or ph meter.

 

[antichode]

Thanks. I was keen to get a ballpark for the amount. Sometimes I spend quite some time titrating a little at a time when I could get to a close ph quickly with a bit of calculation then finish it off by watching ph.


Thanks for the link

 

[Varallo]

Thanks. I was keen to get a ballpark for the amount. Sometimes I spend quite some time titrating a little at a time when I could get to a close ph quickly with a bit of calculation then finish it off by watching ph.


Thanks for the link

Don’t forget that the sulfuric acid is diprotic. So it will bind two mescaline molecules to form the salt.

 

[fiM]

Hey I'm interested in your method are you planning on doing liquid ,base+ citrate with EA getting citrate back into EA then adding sulfate,,,, or is their a better way,,,,,,probly should have just used the sulf and skipped the citric acid but we can't be perfect all the time