Scientific Articles on DMT/Ayahuasca/Psychedelics

[bufoman]

Interesting new article. Psychedelics and the Human Receptorome:

Psychedelics and the Human Receptorome

We currently understand the mental effects of psychedelics to be caused by agonism or partial agonism of 5-HT2A (and possibly 5-HT2C) receptors, and we understand that psychedelic drugs, especially phenylalkylamines, are fairly selective for these two receptors. This manuscript is a reference...

www.plosone.org

Looks at affinity of a variety of hallucinogens at a large number of human CNS receptors.

 

[benzyme]

Efficient and Sensitive Method for Quantitative Analysis of Alkaloids in Hardinggrass (Phalaris aquatica L.)

 

[benzyme]

Dimethyltryptamine and other hallucinogenic tryptamines exhibit
substrate behavior at the serotonin uptake transporter
and the vesicle monoamine transporter (Dec. 2009)

 

[D_Juggz]

°Reassessing the Cultural and Psychopharmacological Significance of B.Caapi: Preparation, Classification and use among the Piaroa of Southern Venezuela (R.Rodd)
°Evidence of health and safety in American members of a religion who use a hallucinogenic sacrament (J. Halpern)
°Do hallucinogens cause residual neuropsychological toxicity? (J.Halpern)
°Maripa: To know everything the experience of power as Knowledge derived from the integrative mode of conciousness (R.Rodd)
°Clinical investigations of the therapeutic potential of ayahuasca: rationale and regulatory challenges (McKenna)
°Ayahuasca healing beyond the Amazon: the globalization of a traditional indigenous entheogenic practice (KENNETH W. TUPPER)
°Psychometric assessment of the Hallucinogen Rating Scale (Jordi Riba , Antoni Rodrı ´guez-Fornells, Rick J. Strassman c, Manel J. Barbanoj)
°The globalization of ayahuasca: Harm reduction or benefit maximization? (KENNETH W. TUPPER)

 

[Infundibulum]

"Effects of monoamine oxidase inhibitor and cytochrome P450 2D6 status on 5-Methoxy-N,N-dimethyltryptamine Metabolism and Pharmacokinetics"

 

[Elpo]

Ok here are some articles on the Hopkins University study on psilocybin.

Study

commentaries on the study

Q&A with researcher Griffiths

I hope this can be useful.


Peace
Elpo

 

[Ginkgo]

A small portion of my library... Couldn't upload anything over a few MBs due to a timeout error, but I hope you guys will like what I was able to upload!

 

[endlessness]

great collection there

here's a couple more that were posted in this and this thread:

1- Su TP, Hayashi T, Vaupel DB. When the endogenous hallucinogenic trace amine N,N-dimethyltryptamine meets the sigma-1 receptor. Sci Signal. 2009 Mar 10;2(61) : pe12.

2- Bradnt S, Martins, C. Analytical methods for psychoactive N,N-dialkylated tryptamines TrAC Trends in Analytical Chemistry
Article in Press, Accepted Manuscript

3- Fontanilla D, et al. The Hallucinogen N,N-Dimethyltryptamine (DMT) Is an Endogenous Sigma-1 Receptor Regulator.Science 323, 934 (2009)

 

[Shaolin]

Be resurrected oh mighty thread:

Meckes-Lozoya M, Lozoya X, Marles RJ, et al. "N,N-Dimethyltryptamine Alkaloid in Mimosa tenuiflora bark (tepescohuite)". Arch Invest Med (Mex). 1990;21(2):175–7.

Anton R, Jiang Y, Weniger B, Beck JP, Rivier L. "Pharmacognosy of Mimosa tenuiflora (Willd.) Poiret."

Vepsäläinen JJ, Auriola S, Tukiainen M, et al. "Isolation and Characterization of Yuremamine, a New Phytoindole". Planta Medica. 2005;71(11):1053–7.

Melo, A. C. and Bandeira, J. A. (1961), . Contribuição ao estudo químico e farmacológico do alcalóide da Jurema Preta (Mimosa hostilis

Camargo-Ricalde, S. L. (2000), Descripción, distribución, anatomía, composición química y usos de Mimosa tenuiflora (Fabaceae-Mimosoideae) en México Revista Biologica Tropical, 48, 939-954.

Nicasio Mdel P, Villarreal ML, Gillet F, Bensaddek L, Fliniaux MA. (2005) "Variation in the accumulation levels of N,N-dimethyltryptamine in micropropagated trees and in in vitro cultures of Mimosa tenuiflora."

 

[endlessness]

Be resurrected oh mighty thread:

Vepsäläinen JJ, Auriola S, Tukiainen M, et al. "Isolation and Characterization of Yuremamine, a New Phytoindole". Planta Medica. 2005;71(11):1053–7.


Camargo-Ricalde, S. L. (2000), Descripción, distribución, anatomía, composición química y usos de Mimosa tenuiflora (Fabaceae-Mimosoideae) en México Revista Biologica Tropical, 48, 939-954.

here:

 

[Shaolin]

^^ Thank you my friend.

 

[universecannon]

Came across this and was discussing it in the chat. Not sure what most of it means though to be honest; it just reminds me of the concept in The Invisible Landscape
Looks interesting though

B carbolines bind to dna

 

[Shaolin]

All I want in 2010 is :

Characterization of the synthesis of N,N-dimethyltryptamine by reductive amination using gas chromatography ion trap mass spectrometry
Simon D. Brandt, Sharon A. Moore1, Sally Freeman2, Abu B. Kanu3

N,N-Dimethyltryptamine and dichloromethane: Rearrangement of quaternary ammonium salt product during GC–EI and CI-MS–MS analysis
Simon D. Brandt, Cláudia P.B. Martinsb, Sally Freemanc, Nicola Dempstera, Mark Wainwrighta, Philip G. Ribya and John F. Alderb

Halogenated solvent interactions with N,N-dimethyltryptamine: Formation of quaternary ammonium salts and their artificially induced rearrangements during analysis
Simon D. Brandt, Cláudia P.B. Martinsb, Sally Freemanc, Nicola Dempstera, 1, Philip G. Ribya, 1, Jochen Gartzd and John F. Alderb

Thank you.

 

[endlessness]

Here, I was able to retrieve the last two:

 

[Shaolin]

The viscosity of diesel oil and mixtures with straight vegetable oils: Palm, cabbage palm, cotton, groundnut, copra and sunflower - Abollé Abollé, Loukou Kouakoua and Henri Planchea

G33k speak to the fullest

 

[Infundibulum]

The viscosity of diesel oil and mixtures with straight vegetable oils: Palm, cabbage palm, cotton, groundnut, copra and sunflower - Abollé Abollé, Loukou Kouakoua and Henri Planchea

G33k speak to the fullest

Here ya go!

 

[Shaolin]

The viscosity of diesel oil and mixtures with straight vegetable oils: Palm, cabbage palm, cotton, groundnut, copra and sunflower - Abollé Abollé, Loukou Kouakoua and Henri Planchea

G33k speak to the fullest

Here ya go!

What can I say. Thank you again and again.

Solubility of 1-malic, i-malic and fumaric acid in some common organic solvents and in mixtures of the latter with ether or benzene -Descamps, R., Bull. Soc. Chim. Belg. 1940, 49, 91–102

This might help with the "fumaric solubility mistery".

 

[endlessness]

A novel extraction procedure for psilocybin and psilocin determination in mushroom samples
Planta Med. 1990 Jun;56(3):327-8.
Kysilka R, Wurst M.


It basically shows the ideal solvent and solvent mixture for ethanol and methanol + water for extracting psilocybin and psilocin

+

Extraction and analysis of indole derivatives from fungal biomass
Journal of Basic Microbiology, 1994, 34(1):17-22.
Jochen Gartz


(also details mushroom extraction)

+ Shulgin commenting on these extractions

(just some good files for mushroom extraction info)

 

[Mydriasis]

Chem Pharm Bull (Tokyo). 1991 Jul;39(7):1792-5.
Metabolic fates of L-tryptophan in Saccharomyces uvarum (Saccharomyces carlsbergensis).
Shin M, Shinguu T, Sano K, Umezawa C.

Metabolic fates of L-tryptophan in Saccharomyces uvarum (Saccharomyces carlsbergensis) - PubMed

The metabolism of L-tryptophan by Saccharomyces uvarum (carlsbergensis) was investigated by simultaneous measuring of fluxes through kynureninase, through transaminases and into protein using L-[methylene-14C] and L-[side chain-2,3-3H]tryptophan. In yeasts cultivated in synthetic medium (S...

www.ncbi.nlm.nih.gov

Pleasey pleasey please please?:lol:

 

[endlessness]

TLC info on Gramine, 5-MeO-DMT, DMT and other alkaloids as posted here

1978 W. MAJAK. R E MCDiarmid and R. J. Bose. "TLC luminescence of gramine and related indole alkaloids in Phalaris arundinacea". Phytochemistry, Vol 17, 301-303