What is the ancient Soma or Haoma?

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I think that's very possible, but I think genetics are likely to play a role as well. My girlfriend (I know I bring her up often about this topic, sorry) has entered visionary states with only extracted rue alkaloids, and in those occasions I also had rue and we had been eating almost the same daily for quite some time (except in amount, I eat much more!). Although it could plausibly be a case of sensitivity only, where she's more sensitive and I would have reached similar states with a higher dose.

One more thing, I was specifically intending to refer to the subjective variation experienced by one individual from the same batch of seeds, rather than the variation experienced between individuals from the same batch of brew.