AluminumFoilRobots
gufyg
Hello!
So I have recently began experimenting with this fascinating and generally unknown psychedelic known as 25i-NBOMe. It seems to me that at within a (somewhat scarily small) dosage window, profound insights and beautiful visuals are quite within grasp. It's very forgiving, at least at the doses I have taken, and so lucid and clear that it seems to me that there is less chance of getting "lost in the woods" so to speak - which is always a looming possibility with the molecule that I've been making the most of lately (DMT primarily pharma).
I had 5 pre-made blotters, taking one to test the stuff out, finding that dose to be unspectacular and more of a strange MDMA-type experience. 4-5 days later I take two doses, and had a blissful experience and having lots of very unique effects that I have never come across before... very stereotypical american "60's" stuff which I have never had like purple/magenta phosphorescent smoke billowing everywhere, numbers melting off of clocks, that sort of thing. I had good mental trains going on (like perhaps the machines should have won the matrix) but no "visions" in the ayahuasca/jurema sense. But it seemed wholesome and nice.
However, one drawback with the substance is that there is an extremely long tolerance curve, apparently something on the order of two weeks, which supposedly goes even longer if one redoses too soon. Does anyone think or know through experience whether or not that tolerance would also dampen or defeat the effects of, say, oral DMT via ayahuasca analogue? What about LSD? If there is a tolerance lasting that long, would it apply at least somewhat to all serotonergic psychedelics?
Also, just as a curiosity, how does such a tolerance develop? Desensitization or down-regulation of 5-HT2a and 2c receptors? Or some other mechanism? are there any drugs using similar pathways that do not cause cross-tolerance with one another?
Anyway thanks!
So I have recently began experimenting with this fascinating and generally unknown psychedelic known as 25i-NBOMe. It seems to me that at within a (somewhat scarily small) dosage window, profound insights and beautiful visuals are quite within grasp. It's very forgiving, at least at the doses I have taken, and so lucid and clear that it seems to me that there is less chance of getting "lost in the woods" so to speak - which is always a looming possibility with the molecule that I've been making the most of lately (DMT primarily pharma).
I had 5 pre-made blotters, taking one to test the stuff out, finding that dose to be unspectacular and more of a strange MDMA-type experience. 4-5 days later I take two doses, and had a blissful experience and having lots of very unique effects that I have never come across before... very stereotypical american "60's" stuff which I have never had like purple/magenta phosphorescent smoke billowing everywhere, numbers melting off of clocks, that sort of thing. I had good mental trains going on (like perhaps the machines should have won the matrix) but no "visions" in the ayahuasca/jurema sense. But it seemed wholesome and nice.
However, one drawback with the substance is that there is an extremely long tolerance curve, apparently something on the order of two weeks, which supposedly goes even longer if one redoses too soon. Does anyone think or know through experience whether or not that tolerance would also dampen or defeat the effects of, say, oral DMT via ayahuasca analogue? What about LSD? If there is a tolerance lasting that long, would it apply at least somewhat to all serotonergic psychedelics?
Also, just as a curiosity, how does such a tolerance develop? Desensitization or down-regulation of 5-HT2a and 2c receptors? Or some other mechanism? are there any drugs using similar pathways that do not cause cross-tolerance with one another?
Anyway thanks!
