dangerous combo ? MXE+DMT

[Cercle]

Hello nexians

I was doing research on methoxetamine, i a came across information that MXE is acting on serotonine (where ketamine doesn't).

DMT is also an agoniste for serotonine.

Is there's any possibilities of serotonine syndrome ?

I've try the combination a few time and i found it really interesting, breaking really smoother and a lot more psychedeliq.i've really enjoyd it.

Any tought about the danger of getting a synddrome and about this combo are welcome.

 

[Jorkest]

ive mixed mxe with dmt with GREAT success...

i have even taken it with harmine and dmt orally

my dose is 80mg harmine 18mg mxe and 18mg dmt..all mixed up together in a capsule..

this may seem like a very light dose..but im super sensitive..my friend took the same dose and only felt the mxe mostly...he may have needed more harmine..and a dash more dmt

a very very enjoyable combo..

just remember though that this combo is also super strong..ive taken 130mg harmine 30mg mxe and 25mg dmt and i couldnt speak for 2 hours..or stand...or anything...and then when i came out of it..my balance was very off and i kept falling over..so be careful moving around on this combo..its best to stay somewhere cozy and safe...

when smoking dmt and taking mxe..its also SUPER heavy and makes it much more...deep..it really pushes you far into hyperspace...i enjoyed it everytime ive tried it


and do you have a source for that info about mxe and serotonin

 

[Pandora]

I've taken low to medium doses of MXE, in the 20-35 mgs range and smoked DMT and found the combination to be delightful. It's never gotten me into any sort of trouble.

Whereas, I have had a singular incident involving using a less than dissociative dose of K then taking DMT and winding up feeling radically overheated. Other than that singular incident, I found that combo to be delightful also.

I'm on a long term dissociative break. But still consuming DMT a couple/few times a year. Nothing like naked DMT with nothing else in the mix. Just saying . . . .

 

[corpus callosum]

20-30mg MXE with 50mg changa (caapi x 11 : DMT in a 1:1 ratio) was absolutely incredible; as Jorkest mentioned, it goes VERY deep. The duration with smoked harmalas was prolonged slightly, but my abiding memory was of less pace to the experience.For me, an exceptional combination. :thumb_up:

 

[chaosbydesign]

I once had about 25mgs of MXE, and then smoked about 30mg of DMT about 10 minutes later. I had VERY out of this world, even explosive, results. More visual than usual, as well. I met an entity that was very POINTY (reminded me of the Pokémon bird Zapdos- yellow electric legendary bird, haha.. and for those who enjoy puns.. this experience *was* kind of a "Zap-dose").. I literally felt like I was cut by the sharpness of the entity... it was kind of painful. I must say that it wasn't the most pleasant experience, and for some reason I was stunned for a good ten minutes by what I had experienced. However, I didn't notice anything that felt 'unhealthy' or unsafe about the combination. Perhaps if one took a really large dose of MXE, however, that could change...

 

[soulfood]

This is probably my favourite combo I've tried so far.

You don't really need much MXE and to get the best results you have to time it just right. It seems there's a moment a little while after the MXE seems to be waning, that it has a synergist effect with the DMT which is akin to harmaloids, had they dropped out of school and joined the circus. I often had a feeling the DMT hadn't worked, then 30 seconds after placing my pipe down, things got very strange.

 

[chaosbydesign]

This is probably my favourite combo I've tried so far.

You don't really need much MXE and to get the best results you have to time it just right. It seems there's a moment a little while after the MXE seems to be waning, that it has a synergist effect with the DMT which is akin to harmaloids, had they dropped out of school and joined the circus. I often had a feeling the DMT hadn't worked, then 30 seconds after placing my pipe down, things got very strange.

"Had they dropped out of school and joined the circus" hahaha that's actually perfect!

You have a good point about the unique synergy, and I actually noticed the delayed effect too..... I ended up having a *ton* of hits... then it hit me all at once. Heh, also right as the MXE was coming up.. Maybe that's why I seriously felt like I was being intensely zapped or whacked with an ego-shattering sledgehammer... but somehow in a good, "this is necessary for a personal reformatting" kinda way if that makes sense.

 

[Hyperspace Fool]

I see that this is an older thread that got bumped, but I have been a proponent of the dissos and MXE around here for some time, so I might as well chime in. (note: There was a time when we couldn't even talk about MXE here, and popular opinion on the Nexus was rather low... glad to see this has changed)

I must concur with my esteemed colleagues, that MXE blends wonderfully with DMT.

I don't see the combo as being a potential catalyst for Serotonin Syndrome... at least not without any SSRI's in the mix. This tends to be the case for serotonergic psychs. Don't go stacking them and using them with SSRI's and you should be fine. I think people shouldn't take most SSRI's anyway. Of course, every case is different, and people need to do their research and know their bodies.

As for MXE-DMT in practice, I think that the "waning" synergy spoken of is a real thing... even more so with DXM to be frank. I have written about this before in my old DXM Redux thread. However, DMT goes well at any point in the MXE journey, so long as one is not having a rough patch. In general, the dissocation is a real plus for people who get pre-flight jitters, or have trouble letting go. Dissos have that wonderful ability to dissolve boundaries, so the expansive consciousness and lack of obstacles can be an eye opener for those used to smoalking pure. Instead of revving up and smashing through... a breakthrough can be had via MXE & DMT by simply taking a relatively small amount and holding hit while you pleasantly slide on through an open and grand archway.

Only comments on MXE are that you MUST hydrate. MUST MUST MUST. It is very dehydrating, and you generally will piss more than you have consumed. I really have to force myself to chug until it is uncomfortable.... wait, and chug some more. And then do that again periodically.

Okie doke... peace out.
HF