Dmso

[Tiedyemafia]

DMSO as a carrier for DMT into the blood stream via topical route any info/speculations?

 

[Tiedyemafia]

And I googled DMSO DMT and for that this has been asked. So I'll dig through those but still would appreciate input.

 

[pitubo]

A very cursory search of the nexus forums for threads with "transdermal" in the title returned a few results, of which these may be relevant to you:

The TRANSDERMAL DMT Thread
Transdermal DMT
DMSO - Transdermal

Perhaps you may find more information through creative use of the forum search engine.

 

[Tiedyemafia]

Yeah I found the info I wanted. Basically it works with DMSO under the tongue but with 50-100mg. Topically not viable because it's slow absorbsion rate.

 

[entheogenic-gnosis]

In the 1960s Abbie Hoffman devised his "lace vs. Mace" concept, the notion was that as police forces were coating demonstrators in pepper spray and chemicals against their will, that in retaliation the demonstrators should spray police with a mixture of Lysergic acid diethylamide and Dimethyl-sulfoxide. It was claimed that the DMSO would allow LSD to absorb through the skin, resulting in psychoactivity.

This DMSO/LSD concept was popularized again by the musical group "the dead kennedys"

D. M. S. O.
Crypto Wonder Drug
In vogue
Some people say
It cures arthritis
Maybe that's why
It keeps getting banned
It's absorbed
Directly through the skin
Mix it with lemon juice
Touch your fingertips
You'll taste the lemon
The police
Started a riot
Down at the courthouse
Again
Running amok
Spilling blood
Bashing heads
I do my part
Behind the lines
Swabbing door handles of cop cars
With D.M.S.O.
Mixed with L.S.D

-Dead kennedys;DMSO

Also, in a lecture by David E. Nichols, Nichols mentions Nick Sand telling him that DMSO/LSD had no effect:

Another fact: I've made LSD in my lab on many occasions for research purposes, possibly in not so meticulous a manner as Albert Hofmann. Nothing ever happened. I had several graduate students who made LSD as an intermediate for projects. No accidental ingestion of LSD ever occurred. A technician in my lab makes it routinely because we use it as a drug to train our rats. He's learned by experience that he never gets high, nothing ever happens. And yesterday I was talking to Nick Sand, and Nick said, "I made a solution of LSD in DMSO…" -- DMSO (dimethyl sulfoxide) is a chemical that greatly enhances absorption of other chemicals through the skin -- he says, "…I painted it on my skin. Nothing happened." A concentrated solution and nothing happened! How did this very meticulous Swiss chemist get the LSD into his body? I don't know

Erowid Conference Vault : Mindstates IV (2003) : LSD Panel - David Nichols, Ph.D.

Hypothesis on Albert Hofmann's Famous 1943

erowid.org

DMSO does not really work with DMT either, but it's an interesting concept, solvents which would allow transdermal absorption of psychedelic compounds...


-eg